Allergy & Immunology Flashcards

1
Q

Co-stimulatory effect on T cells

A

IL-1

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2
Q

Enhances antigen presentation

A

IL-1

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3
Q

Primary T-cell growth factor

A

IL-2

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4
Q

B-cell and NK-cell growth factor

A

IL-2

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5
Q

Required for T-regulatory cell function and survival

A

IL-2

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6
Q

Mast cell growth factor

A

IL-3

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7
Q

Multicolony-stimulating factor

A

IL-3

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8
Q

T-cell growth factor

A

IL-4

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9
Q

Enhances IgE synthesis

A

IL-4

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10
Q

Enhances B-cell differentiation

A

IL-4

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11
Q

Mast cell growth (2)

A

IL-4, IL-9

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12
Q

Enhances eosinophil differentiation

A

IL-5

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13
Q

Enhances immunoglobulin synthesis (3)

A

IL-5, IL-6, IFN-gamma

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14
Q

Enhances IgA synthesis (2)

A

IL-5, IL-6

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15
Q

Antiviral activity

A

IL-6

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16
Q

Hematopoietic effects

A

IL-6

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17
Q

Enhances growth of pre-T cells

A

IL-7

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18
Q

Neutrophil-activating protein

A

IL-8

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19
Q

T lymphocyte and neutrophil chemotactic factor

A

IL-8

20
Q

Acts in synergy with IL-_ to induce IgE production

A

IL-9, acts in synergy with IL-4

21
Q

Cytokine synthesis inhibitory factor

A

IL-10

22
Q

Suppresses macrophage function

A

IL-10

23
Q

Enhances B-cell growth (2)

A

IL-10, IL-13

24
Q

Inhibits IL-12 production

A

IL-10

25
Q

Suppresses inflammation at mucosal surfaces

A

IL-10

26
Q

NK cell stimulatory factor

A

IL-12

27
Q

Cytotoxic lymphocyte maturation factor

A

IL-12

28
Q

Enhances IFN-gamma synthesis (2)

A

IL-12, IL-18

29
Q

Inhibits IL-4 synthesis

A

IL-12

30
Q

Enhances IgE synthesis

A

IL-13

31
Q

Inhibits macrophage activation

A

IL-13

32
Q

Causes airway hyperreactivity

A

IL-13

33
Q

Induces IL-1B and IL-6 synthesis

A

IL-17

34
Q

Important in fungal infections

A

IL-17

35
Q

Macrophage activation

A

IFN-gamma

36
Q

Inhibits IgE synthesis

A

IFN-gamma

37
Q

Inhibits T-cell and B-cell proliferation and activation

A

TGF-B

38
Q

Induces T regulatory cells

A

TGF-B

39
Q

Chemokine for monocytes (2)

A

RANTES, IP-10

40
Q

Chemokine for T cells (2)

A

RANTES, MIP-1a

41
Q

Chemokine for Eosinophils (2)

A

RANTES, Eotaxin 1/2/3

42
Q

Enhances differentiation of CD4+ T cells

A

MIP-1a

43
Q

Chemokine for basophils

A

Eotaxin 1/2/3

44
Q

Chemokine for Th2 cells

A

Eotaxin 1/2/3

45
Q

Chemokine for activated T cells

A

IP-10

46
Q

Chemokine for NK cells

A

IP-10