allergy and immunology Flashcards
are the most common cause of acquired angioedema
ACE inhibitors
remember family medicine precipitation of acute renal failure in patients with bilateral renal artery stenosis.
UR dX AND mX
Acute urticaria
no additional evaluation.
2nd-generation H1 antihistamines
Add H2 antihistamines or systemic corticosteroids if severe
Two-thirds of cases self-resolve
Recurrent bacterial infections in an adult should raise suspicion for common variable immunodeficiency. Quantitative measurement of serum immunoglobulin levels is needed to establish the diagnosis
Symptom onset classically age 20-40, as early as puberty
Recurrent respiratory infections (eg, pneumonia, sinusitis, otitis)
Recurrent GI infections (eg, Salmonella, Campylobacter, Giardia)
Chronic disease:
Autoimmune (eg, RA, thyroid disease)
Pulmonary (eg, bronchiectasis, fibrosis)
GI (eg, chronic diarrhea, IBD-like conditions)
THEmajor cause of morbidity and mortality in patients who have undergone liver transplantation
Recall the time regarding each :
BACTERILA INFECTIONS :
<1 month: Bacterial causes from operative complications (eg, hepatic abscess, biliary leak, wound infection) or hospitalization (eg, intravascular catheter, external drain)
Months 1-6: Opportunistic pathogens (eg, Cytomegalovirus, Aspergillus, Mycobacterium tuberculosis) in the setting of high-dose immunosuppressive medication
> 6 months: Immunosuppressants usually at maintenance levels. Patients primarily at risk for typical community-acquired pathogens (at a higher rate than the general population)
photosensitive rash, along with multisystemic symptoms (eg, arthralgias, pancytopenia, splenomegaly),
u suspect ————-
and ur Mx
**The antinuclear antibody assay is highly sensitive for SLE.
raises concern for systemic lupus erythematosus (SLE).
Calcineurin inhibitors (eg, tacrolimus, cyclosporine) have a wide range of adverse effects, including nephrotoxicity, hypertension, neurotoxicity (eg, tremor), and ————–
impaired glucose control
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