Allergy Flashcards
What types of food allergy are there?
- IgE mediated food allergy
- Non-IgE mediated food allergy
- Non-allergic food hypersensitivity
What are the clinical features of mild IgE mediated food allergy?
Mild = Skin
- Urticaria & Itchy Skin
- Facial swelling
What are the clinical features of severe IgE mediated food allergy?
Severe = Airway + Systemic
- Wheeze
- Stridor
- Abdominal Pain, Vomiting. Diarrhoea
- Shock, Collapse
What are the clinical features of non-IgE mediated food allergy?
- Loose Stools
- Faltering Growth
- Elimination of food results in resolution of symptoms–> Symptoms return on reintroduction
What are the clinical features of non-allergic food hypersensitivity?
Diarrhoea and Vomiting
Describe the course of diarrhoea and vomiting in non-allergic food hypersensitivity
Diarrhoea–> continues for several weeks
Vomiting–> Settles quickly
How do you investigate IgE mediated food allergy?
- Skin-prick test
2. Blood test for specific IgE antibodies
How do you investigate for non-IgE mediated food allergy?
- Hx and Examination
2. Endoscopy & Intestinal biopsy–> Presence of eosinophillic infiltrates
How do you investigate for non-allergic food hypersensitivity?
take stool samples and test for reducing substances
What is the gold standard for diagnosing food allergy in general?
Exclusion of relevant food under dietician supervision, followed by double-blind placebo-controlled food challenge
How do you manage food allergy?
- Avoidance of relevant food
- Written self-management plans
- Non-sedating antihistamines
- Epipen (if high risk or severe reaction)
What are the clinical features of Allergic Rhinitis?
Coryzal Symptoms + Conjunctivitis
Mouth breathing
Pale/swollen inferior nasal turbinates
Hyperinflated chest/ Harrison Sulci
What other conditions is Allergic Rhinitis associated with?
- Eczema
- Sinusitis
- Adenoidal Hypertrophy
- Asthma
How do you manage Allergic Rhinitis?
- 2nd generation non-sedating antihistamines
- Topical corticosteroid
- Cromoglycate eye drops
- Leukotriene Receptor Antagonist–> Montelukast
- Nasal decongestants
***DO NOT USE SYSTEMIC CORTICOSTEROIDS
What is anaphylaxis?
Severe, life-threatening, generalised/systemic hypersensitivity reaction