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PET
Radionuclei which emit positrons ino the body. Gamma rays prod. when the positrons encounter with el.
Concentional linar/ axial tomography
- Conventional: x-ray tube + film linked together
- Axial: image of a slice of the body
Doppler effect
Change in frequency of a wave, observed when the source of waves is moving with respect to the detector.
In-vitro/in-vivo use of radioisotopes
In-vitro: determine amount of hormones. Manily RIA.
In-vivo: diagnostic of thyroid gland - iodine uptake measurement.
Stochastic/deterministic effects
Stochastic: frequency of damage, but not severity, depends on the dose without threshold. Heritable and carcinogenic.
Deterministic: result from collective injury of many cells. E.g.lens cataract.
Radiation units
- Source activity: nr. of decays in unit time - becquerel
- Exposure: amount of radiation reaching the material-röntgen
- Absorbed dose: energy absorbed by unit mass of material from ionizing radiations-gray
- Dose equivalent: effect on bio.system-sievert
Alpha, beta and gamma radiations
- Aplha: +charge - helium nucleus He2+
- Beta: an electron, mostly neg.charge - can be positron
- Gamma: EM radiation (light, x-rays, etc)
Oscilloscope
El.gun with accelerating anode. Electron test instrument that observes signal voltages.
ECG-signal
- 0.25s,small increase-depolarization
- 0.5s, high peak-ventricle depolarisation and contraction
- Just after peak, small increase-ventricle repolarization
- Repeat
Measurement of membr.pot.
Diff.conc. of ions on either side of membr.
- Electrophysiological - w.electrodes
- Electric potential sensitive staining, or charged
Action potential
-50mV is the critical threshold value. After stimuli, pot.increases-becomes pos. and reaches +50mV. Then return to resting value.
Electromchemical pot.
Depends on gas constant, faraday constant, absolute temp and electrical pot.
Excitability
Electric pot.diff. in each living cell measured between the cytoplasm and extracellular regions.
Resistance/capitance
Cause impedance/resistance in a circuit. Capasitor: pair of conducting sheet sep. by an insulating layer.
Photoeffect/compton scattering/pair production
Photoeffect: x-ray gives E to an el. of an inner shell
Compton scattering_ x-ray hits an outer el. and splits into 2 rays with smaller E
Pair production: photon becomes an el. and positron