All Topics Flashcards

1
Q

Normal ph of the vagina

A

3.8-4.2

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2
Q

Flutamide

  • Moa
  • adverse effects
A
  • antiandrogen
  • most common ae: dry skin
  • associated with hepatitis

“FLUtamide Gives the Liver the FLU and Cracked Skin too”

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3
Q

Most common cause of hemolytic disease of newborn

A

ABO incompatibility

  • 1st preg is worst
  • neonatal jaundice
  • type A in newborn usually
  • IgM so no hydrops fetalis like with Kell, Duffy, Kidd Ab

“ABO Must stay ABOut and Away from the baby”

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4
Q

Most common cause of maternal-fetal group incomptability

A

ABO incompatibility

  • 1st preg is worst
  • neonatal jaundice
  • type A in newborn usually
  • IgM so no hydrops fetalis like with Kell, Duffy, Kidd Ab

“ABO Must stay ABOut and Away from the baby”

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5
Q

Most common type of nonproliferative breast lesion

A

Breast cyst

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6
Q

5 Causes of bloody nipple discharge

Clue: TIIPP of the breast

A
Trauma
Infection - mastitis
Intraductal carcinome
Papilloma
Pagets disease 

“Bleeding at the TIIPP of the breast”

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7
Q

Osteopenia definition

A

Between -1 to -2.5

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8
Q

Osteoporosis and severe osteoporosis definition

A

Osteoporosis below -2.5

Severe osteoporosis below -2.5 + fracture

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9
Q

Hormons from anterior pituitary

Clue: FLATPG

A

FSH LH ACTH TRH Prolactin GnRH

“FLAT PG”

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10
Q

Hormones of the Posterior pituitary

A

Oxytocin ADH

- same alpha subunit

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11
Q

1st sign of sheehan syndrome

A

Failure of lactation

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12
Q

Name 3 primary estrogens of the body and its origin

Clue: One Two Three

A

estrONE - one body menopause
estraDIol - two ovaries
esTRIol - three mom/baby/placenta or trimesters

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13
Q

Different between Duffy Fya and Duffy Fyb

A

Fya - Awful like “Fire” causing erythroblastosis fetalis

Fyb - Better so baby lives

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14
Q

Enzyme that convertes 17 hydroxyprogesterone to androstenedione

A

21 hydroxylase

- if deficient, get inc steroid production —> virilization, CAH

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15
Q

Organ that makes DHEA

A

Adrenal glands

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16
Q

Enzyme that converts testosterone to dihydrotestosterone

A

5 alpha reductase

- if deficient, no external male genitalia

17
Q

Enzyme that converts testosterone to estrogen

A

Aromatase

- inhibitors: letrozole (for fibroids, endometriosis) and anastrozole (for breast cancer)

18
Q

Ag that cause erythroblastosis fetalis

A

Kell - Kills
Kidd - Kills
Duffy fya - Dies

19
Q

Ag that cause severe hemolytic disease

A

EDC and Kell

“Kell Kills the EDC baby”

20
Q

Enzyme that converts 17 hydroxypregnenolone to 17 hydroxyprogesterone

A

17 alpha hydroxylase

- if deficient, inc in mineralocorticoids —> HTN, high Na

21
Q

Inherited thrombophilias and mode of inheritance

Clue: Mother of V PACS

A
Factor V 
Prothrombin 3 G20210A
Antithrombin 3 
Protein c
Protein s
MTHFR 
- all AD except for MTHFR which is AR
“Mother of V-Dominant-PACS”
22
Q

Complication with inherited thrombophilia

A

DVT/PE

23
Q

Complication w acquired thrombophilia

A

Stillbirth

24
Q

Different treatments for lichen planus

A
Cyclosporine
Systemic corticosteroids
Hydroxyquinoline
Methotrexate
Clobetasol
25
Q

Lichen planus features

A
  • hardest to tx
  • multiple meds
  • assoc w desquamative inflammatory vaginitis (tx: clindamycin)
  • wickham striae
26
Q

Lichen sclerosis features

A
  • cigarette paper
  • thinning
  • figure of 8 (perianal involvement)
  • assoc with SCC
  • loss of rete pegs
  • tx: clobetasol
27
Q

Lichen simplex chronicus features

A
  • pruritic
  • leathery
  • tx: clobetasol
28
Q

Puberty stages

Clue: BPAM

A

Breast
Pubarche
Adrenarche
Menarche

29
Q

Most precise method to evaluate pregnancy affected by alloimmunization

A

MCA dopplers for fetal anemia

30
Q

Best test for diagnosis of VWD

A

Ristocetin co factor activirt

31
Q

Most common bleeding disorder

A
Von Willebrand’s disease
Types:
1
2
3
32
Q

Most common cause of non-maternal death

A

1) homicide

2) MVA

33
Q

What is direct maternal death?

A

Death of mom resulting from ob complication during labor, postpartum, or from interventions, omissions, incorrect tx, or chain of events resulting from any of these

Ex - hemorrhage, eclampsia, uterine rupture

34
Q

What is indirect maternal death?

A

Death of mom resulting from previous existing disease or disease that devloped during pregnancy that was no due to obstetric causes but was aggravated by physiological effects if pregnancy

Ex - cardiac disease, lupus, rheumatoid, HIV, DM, sickle cell disease