ALL THINGS PANCREAS & GB- FINAL Flashcards
possible complication of acute pancreatitis
abscess formation
gross appearance of acute pancreatitis
loss of the normal lobular surface markings
gross appearance of chronic pancreatitis
shrunken and fibrotic. The main duct is dilated and filled with calcified secretions
complications of acute pancreatitis
pseudocyst- NO EPITHELIAL LINING Infected necrosis (lethal)
Benign tumors of the exocrine pancreas include
pseudopapillary tumor, serous cystadenoma and mucinous cystadenoma
Solid pseudopapillary tumors
gross:
round, well-demarcated, with solid and cystic areas, often with hemorrhage noted on cut sections
the most frequent cystic tumors of the pancreas (50% of all cystic tumors)
Mucinous cystadenomas
Mucinous cystadenomas are usu benign but may transform into
a malignant tumor
second most common cystic tumor of the pancreas
Serous cystadenoma
serous cystadenoma
gross:
histo:
honeycombed appearance on pathology is also characteristically seen on the CT scan
a bx reveals small cysts which are lined by ciliated cuboidal epithelium
serous cystadenoma is known to be associated with
Von Hippel-Lindau syndrome
a genetic condition in which cysts often develop in the pancreas, liver and kidney and hemangioblastomas are found in different organs including the cerebellum, spinal cord, kidney and retina as well as cafe o’lay spots
The most common type of pancreatic cancer
(90 - 95% of all malignant pancreatic tumors) _______
pancreatic adenocarcinoma
generally has a very poor prognosis
stones are formed in the gallbladder but may pass distally into other parts of the biliary tract
cholelithiasis
if gallstones migrate into the ducts of the biliary tract, the condition is referred to as
choledocholithiasis
the presence of stones in the gallbladder (cholelithiasis) can lead to an inflammatory condition called
cholecystitis
Infectious agents that cause cholecystitis include
E. coli, Klebsiella, Pseudomonas, B. fragilis and Enterococcus
gallstone can be divided into 3 types
cholesterol stones
pigment stones
mixed stones
to be classified as cholesterol stones they must be at least
80% cholesterol by weight
what percent of cholesterol stones are radiolucent on XRAY’s?
10%
the other 90% will be negative for cholelithiasis
mixed gallstone typically contain __-__% cholesterol
20-80%
pigment gallstones contain the least cholesterol, with less than ______% cholesterol
20%
_________ is characterized by abnormal deposition of cholesterol and triglyceride fill macrophages in the lamina propria of the gallbladder
cholesterolosis
foci of cholesterol filled macrophages. Diffuse involvement of the mucosa such as in this specimen is referred to as a “strawberry gallbladder”.
cholesterolosis
Rokitansky-Aschoff sinuses are seen in the muscularis for which condition?
chronic cholecystitis
a calcification of the gallbladder believed to be brought on by persistent inflammation due to the presence of gallstones is the pathphysiology for which condition?
porcelain gall bladder
the term used to describe a gall stone that has passed into the common bile duct
choledocholithiasis
concentric (onion skin–like) peri-ductal fibrosis is seen in what two conditions?
ascending cholangitis (secondary sclerosing cholangitis) primary sclerosing cholangitis
The majority of all carcinomas of the gallbladder are found to be well differentiated
adenocarcinomas
adenocarcinoma of the gall bladder shows what types of cells?
intestinal type
