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Pharmacology anticoagulants > all the drugs > Flashcards

all the drugs Flashcards

1
Q

clopidegrol what kind of drug and what does it do?

A

antiplatelet, adp antagonist

can be combined with aspirin to prevent a 2nd MI

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2
Q

ADP Antagonists

A

clopidegrol, dipyridimole, ticlopidine

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3
Q

dipyridimole

A

ADP antagonist

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4
Q

ticlopidine

A

adp antagonist

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5
Q

anagrelide HCl

A

antiplatelet

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6
Q

aspirin

A

antiplatelet

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7
Q

cilostazol

A

antiplatelet

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8
Q

clopidogrel

A

antiplatelet

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9
Q

dipyridamole

A

antiplatelet

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10
Q

prasugrel

A

antiplatelet

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11
Q

ticagrelor

A

antiplatelet

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12
Q

dipyridimole and aspirin can be combined or no?

A

CAN

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13
Q

alteplase also known as?

what kind of drug?

what does it do?

A

tissue plasminogen activator (TPA)

thrombolytic

clot-specific. binds to fibrin surface of clot and promotes conversion of plasminogen –> plasmin

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14
Q

reteplase rPA

A

derivative of TPA.

thrombolytic

lyses thrombi. considered more effective than TPA with less risk of hemorrhage

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15
Q

urokinase

A

thromoblytic

may be used for peripheral arterial occlusion

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16
Q

tenecteplase TNK-tpa (TNKase)

A

thrombolytic

reduces mortality with acute myocardial infarction

‘clot buster’ can be administered in 5 seconds in 1 dose

17
Q

aminocaproic acid

what kind of drug?
what does it do?

A

plasminogen inactivator

controls excessive bleeding from hyperfibrinolysis

18
Q

Clopidogrel

Ther. Uses
MOA
Contra:
side effects

A

THERAPEUTIC USES: to prevent recurrence of MI, stroke; to prevent vascular death
MOA: inhibits platelet aggregation. Prevents ADP from binding with the ADP platelet receptor
CONTRA: intercranial hemorrhage, peptic ulcer, GI bleeding
SIDE EFFECTS: abdominal pain, flulike symptoms, dizziness, epistaxis, headaches, fatigue, chest pain, diarrhea.
ADVERSE REACTIONS: hypotension, bronchospasm

19
Q

abciximab

A

antiplatelet: glycoprotein receptor antagonist

20
Q

eptifibatide

A

antiplatelet: glycoprotein receptor antagonist

21
Q

tirofiban

A

antiplatelet: glycoprotein receptor antagonist

22
Q

dalteparin sodium

A

low molecular weight heparin

23
Q

enoxaparin sodium

A

low molecular weight heparin

24
Q

fondaparinux

A

selective factor Xa inhibitor

25
Q

rivaroxaban

A

selective factor Xa inhibitor

26
Q

apizaban

A

selective factor Xa inhibitor

27
Q

aragatroban

A

direct acting thrombin inhibitor: anticoagulants II (IV)

28
Q

bivilarudin

A

direct acting thrombin inhibitor: anticoagulants II (IV)

29
Q

desiriduin

A

direct acting thrombin inhibitor: anticoagulants II (IV)

30
Q

lepirudin

A

direct acting thrombin inhibitor: anticoagulants II (IV)

31
Q

dabigatran

A

direct acting thrombin inhibitor: anticoagulants II (IV)

32
Q

protamine sulfate

A

anticoagulant antagonist

33
Q

phytonadione, Vitamin K1

A

anticoagulant antagonist

Pharmacology anticoagulants (1 decks)

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