ALL MCQS Flashcards

1
Q

What is an incorrect statement about biological redox reactions?

A

B. Redox reactions are not catalyzed by kinase enzymes, which are involved in phosphorylation.

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2
Q

Which statement is INCORRECT (energy related)?

A

D. Enzymes do not provide energy to make unfavorable reactions occur; they lower activation energy.

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3
Q

Which statement is CORRECT q3?

A

A. In catabolism, large molecules are broken down to release energy.

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4
Q

Which statement is INCORRECT Q4?

A

D. Most vitamins cannot be synthesized in the body; they must be obtained from the diet.

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5
Q

GLUCOSE IS:

A

C. Essential for red blood cells as fatty acids cannot cross the cell membrane.

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6
Q

What are two key features of the coenzyme NAD+?

A

C. NAD+ can be in two forms and can carry electrons and hydrogen ions (H+).

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7
Q

What does digestion of carbohydrates involve?

A

D. Hydrolysis of glycosidic bonds in large polysaccharides to produce smaller oligosaccharides.

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8
Q

Which is NOT involved in glucose absorption from the gastrointestinal tract?

A

A. Facilitative transport through SGLT1 is not the correct mechanism for moving glucose out of epithelial cells.

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9
Q

What is a proposed reason glucose is the preferred fuel for the brain?

A

C. Brain cells have limited access to fatty acids circulating in the blood.

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10
Q

Which statement about using fatty acids as a fuel molecule is CORRECT?

A

A. Fatty acids are the preferred manner to store energy because they require less space than sugars.

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11
Q

What are chylomicrons involved in?

A

C. Chylomicrons are involved in the transport of fatty acids around the body after absorption.

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12
Q

Which statement is INCORRECT about lipase enzymes?

A

B. Lipase enzymes cleave the ester bonds, not the glycerol, to release fatty acids.

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13
Q

Which statement is INCORRECT about lipoproteins?

A

D. Lipoproteins are distinguished by the type of apolipoproteins on their surface, not the type of TAG.

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14
Q

How is fatty acyl-CoA transported into the mitochondrial matrix for β-oxidation?

A

D. Conversion into fatty acyl-carnitine in the intermembrane space and back to fatty acyl-CoA in the matrix.

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15
Q

What do the first three reactions of β-oxidation involve?

A

A. The rearrangement of the bond between the α and β carbons.

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16
Q

Which statement is INCORRECT about the oxidation steps in β-oxidation?

A

B. The oxidation steps in β-oxidation do require coenzymes NAD+ and FAD.

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17
Q

What are the products of the complete oxidation of myristate (C14:0)?

A

B. 7 acetyl-CoA + 6 NADH + 6 FADH2 + 6H+.

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18
Q

What is the energy source in the conversion of succinyl-CoA to succinate?

A

B. The energy comes from the cleavage of Co-A from the succinyl-CoA.

19
Q

Which statement about the citric acid cycle is INCORRECT?

A

C. Acetyl-CoA does not need to be activated to enter the citric acid cycle.

20
Q

How does carbon enter and exit the citric acid cycle?

A

B. Carbon enters as acetyl-CoA and exits as carbon dioxide.

21
Q

What is a likely consequence of inhibiting the citric acid cycle?

A

A. A decrease in the amount of NAD in its reduced form.

22
Q

Which statement is INCORRECT about endopeptidases?

A

D. Endopeptidases cannot hydrolyze peptide bonds between any two amino acids, they have specificity.

23
Q

What does protein digestion involve?

A

C. Hydrolysis of peptide bonds by proteases.

24
Q

Which one of the following statements is CORRECT regarding deamination?

A

A. Deamination can occur through a transamination reaction transferring an amino group to a keto acid.

25
In a transamination reaction, what is the carbon substrate without nitrogen?
B. A keto acid.
26
What are the two energetic gradients resulting from the proton gradient across the inner mitochondrial membrane?
C. A chemical/pH gradient and an electrical gradient.
27
What does the chemiosmotic theory for ATP synthesis describe?
B. The coupling of the electron transport chain and ATP synthesis by ATP synthase.
28
Where is the electron transport chain located?
C. Inner mitochondrial membrane.
29
What do carriers in the electron transport chain undergo?
A. Undergo reversible redox reactions.
30
What is the succinate dehydrogenase enzyme shared between?
D. The citric acid cycle and the electron transport chain.
31
What is a possible route for electrons in the electron transport chain?
D. FADH2 ➔ Complex II ➔ CoQ ➔ Complex III ➔ Cyt C ➔ Complex IV ➔ H2O.
32
What happens on exposure to light with artificial liposomes containing bacteriorhodopsin and ATP synthase?
B. ATP is made using the proton gradient generated by bacteriorhodopsin.
33
Where is the FO component of the F1FO-ATP synthase located?
A. Is in the inner mitochondrial membrane.
34
Which one of the following statements about the F1FO-ATP synthase is INCORRECT?
C. Energized substrates are not required for substrate-level phosphorylation to occur in the F1FO-ATP synthase.
35
Which statement concerning stored triacylglycerol (TAG) is CORRECT?
B. Mobilization of stored triacylglycerol is stimulated by adrenaline and glucagon.
36
Which glucose transporter is responsible for insulin-stimulated glucose uptake in muscle and adipose tissue?
D. GLUT4.
37
Which tissue predominantly uses fatty acids as the primary fuel source under resting conditions?
B. Skeletal muscle.
38
Which statement concerning glycogen metabolism is INCORRECT?
A. Glycogen is stored, not circulating in the blood.
39
Which statement concerning glycogenolysis is INCORRECT?
C. Glycogenolysis is stimulated by glucagon, not insulin.
40
Which molecule is NOT a substrate for gluconeogenesis?
B. Citrate.
41
Which statement regarding glucose-6-phosphatase is CORRECT?
D. Glucose-6-phosphatase is essential for the conversion of glucose 6-phosphate to glucose for release during glycogenolysis.
42
Which statement about starvation is INCORRECT?
A. Glucagon, not insulin, activates fuel mobilization pathways during starvation.
43
Which statement is INCORRECT regarding adipose tissue during starvation?
C. Adipose tissue does not provide fatty acids for the brain during starvation, as the brain uses glucose or ketone bodies.