ALL MCQS Flashcards

1
Q

What is an incorrect statement about biological redox reactions?

A

B. Redox reactions are not catalyzed by kinase enzymes, which are involved in phosphorylation.

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2
Q

Which statement is INCORRECT (energy related)?

A

D. Enzymes do not provide energy to make unfavorable reactions occur; they lower activation energy.

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3
Q

Which statement is CORRECT q3?

A

A. In catabolism, large molecules are broken down to release energy.

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4
Q

Which statement is INCORRECT Q4?

A

D. Most vitamins cannot be synthesized in the body; they must be obtained from the diet.

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5
Q

GLUCOSE IS:

A

C. Essential for red blood cells as fatty acids cannot cross the cell membrane.

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6
Q

What are two key features of the coenzyme NAD+?

A

C. NAD+ can be in two forms and can carry electrons and hydrogen ions (H+).

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7
Q

What does digestion of carbohydrates involve?

A

D. Hydrolysis of glycosidic bonds in large polysaccharides to produce smaller oligosaccharides.

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8
Q

Which is NOT involved in glucose absorption from the gastrointestinal tract?

A

A. Facilitative transport through SGLT1 is not the correct mechanism for moving glucose out of epithelial cells.

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9
Q

What is a proposed reason glucose is the preferred fuel for the brain?

A

C. Brain cells have limited access to fatty acids circulating in the blood.

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10
Q

Which statement about using fatty acids as a fuel molecule is CORRECT?

A

A. Fatty acids are the preferred manner to store energy because they require less space than sugars.

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11
Q

What are chylomicrons involved in?

A

C. Chylomicrons are involved in the transport of fatty acids around the body after absorption.

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12
Q

Which statement is INCORRECT about lipase enzymes?

A

B. Lipase enzymes cleave the ester bonds, not the glycerol, to release fatty acids.

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13
Q

Which statement is INCORRECT about lipoproteins?

A

D. Lipoproteins are distinguished by the type of apolipoproteins on their surface, not the type of TAG.

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14
Q

How is fatty acyl-CoA transported into the mitochondrial matrix for β-oxidation?

A

D. Conversion into fatty acyl-carnitine in the intermembrane space and back to fatty acyl-CoA in the matrix.

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15
Q

What do the first three reactions of β-oxidation involve?

A

A. The rearrangement of the bond between the α and β carbons.

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16
Q

Which statement is INCORRECT about the oxidation steps in β-oxidation?

A

B. The oxidation steps in β-oxidation do require coenzymes NAD+ and FAD.

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17
Q

What are the products of the complete oxidation of myristate (C14:0)?

A

B. 7 acetyl-CoA + 6 NADH + 6 FADH2 + 6H+.

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18
Q

What is the energy source in the conversion of succinyl-CoA to succinate?

A

B. The energy comes from the cleavage of Co-A from the succinyl-CoA.

19
Q

Which statement about the citric acid cycle is INCORRECT?

A

C. Acetyl-CoA does not need to be activated to enter the citric acid cycle.

20
Q

How does carbon enter and exit the citric acid cycle?

A

B. Carbon enters as acetyl-CoA and exits as carbon dioxide.

21
Q

What is a likely consequence of inhibiting the citric acid cycle?

A

A. A decrease in the amount of NAD in its reduced form.

22
Q

Which statement is INCORRECT about endopeptidases?

A

D. Endopeptidases cannot hydrolyze peptide bonds between any two amino acids, they have specificity.

23
Q

What does protein digestion involve?

A

C. Hydrolysis of peptide bonds by proteases.

24
Q

Which one of the following statements is CORRECT regarding deamination?

A

A. Deamination can occur through a transamination reaction transferring an amino group to a keto acid.

25
Q

In a transamination reaction, what is the carbon substrate without nitrogen?

A

B. A keto acid.

26
Q

What are the two energetic gradients resulting from the proton gradient across the inner mitochondrial membrane?

A

C. A chemical/pH gradient and an electrical gradient.

27
Q

What does the chemiosmotic theory for ATP synthesis describe?

A

B. The coupling of the electron transport chain and ATP synthesis by ATP synthase.

28
Q

Where is the electron transport chain located?

A

C. Inner mitochondrial membrane.

29
Q

What do carriers in the electron transport chain undergo?

A

A. Undergo reversible redox reactions.

30
Q

What is the succinate dehydrogenase enzyme shared between?

A

D. The citric acid cycle and the electron transport chain.

31
Q

What is a possible route for electrons in the electron transport chain?

A

D. FADH2 ➔ Complex II ➔ CoQ ➔ Complex III ➔ Cyt C ➔ Complex IV ➔ H2O.

32
Q

What happens on exposure to light with artificial liposomes containing bacteriorhodopsin and ATP synthase?

A

B. ATP is made using the proton gradient generated by bacteriorhodopsin.

33
Q

Where is the FO component of the F1FO-ATP synthase located?

A

A. Is in the inner mitochondrial membrane.

34
Q

Which one of the following statements about the F1FO-ATP synthase is INCORRECT?

A

C. Energized substrates are not required for substrate-level phosphorylation to occur in the F1FO-ATP synthase.

35
Q

Which statement concerning stored triacylglycerol (TAG) is CORRECT?

A

B. Mobilization of stored triacylglycerol is stimulated by adrenaline and glucagon.

36
Q

Which glucose transporter is responsible for insulin-stimulated glucose uptake in muscle and adipose tissue?

A

D. GLUT4.

37
Q

Which tissue predominantly uses fatty acids as the primary fuel source under resting conditions?

A

B. Skeletal muscle.

38
Q

Which statement concerning glycogen metabolism is INCORRECT?

A

A. Glycogen is stored, not circulating in the blood.

39
Q

Which statement concerning glycogenolysis is INCORRECT?

A

C. Glycogenolysis is stimulated by glucagon, not insulin.

40
Q

Which molecule is NOT a substrate for gluconeogenesis?

A

B. Citrate.

41
Q

Which statement regarding glucose-6-phosphatase is CORRECT?

A

D. Glucose-6-phosphatase is essential for the conversion of glucose 6-phosphate to glucose for release during glycogenolysis.

42
Q

Which statement about starvation is INCORRECT?

A

A. Glucagon, not insulin, activates fuel mobilization pathways during starvation.

43
Q

Which statement is INCORRECT regarding adipose tissue during starvation?

A

C. Adipose tissue does not provide fatty acids for the brain during starvation, as the brain uses glucose or ketone bodies.