All Kirila Lectures Flashcards
Which diuretics cause acidosis?
CAI
K+ sparing
How does the paCO2 compensate for HCO3 in metabolic alkalosis?
PaCO2 INC .7 for every 1 INC in HCO3
Drug to treat BPH?
Contraindication?
Alpha-1 antagonist (terazocin)
Selective Beta blocker
Who does atherosclerosis occur most often in?
Bilateral or not?
Associated risks?
Males older than 50
33% bilateral
Tobacco, lipids, DM
What are the 3 types of coarctation?
Interrupted
Pre ductal
Postductal
What is diminished in the early stage of CKD?
Reserve function
Elevated BUN plus confusion is what?
Uremia
Rib notching on PA chest and 3-sign on lateral chest with cardiomegaly indicate what?
Coarctation of heart
What can cause a blockage in the urethra???
Stricture
Congenital valve
Phimosis
What drug to treat migraines?
Beta blocker
CCB
Renal vein renin ratio of what indicates a dx of renovascular HTN?
1.5 or greater
What fibromuscular dysplasia occurs in infants and young adults more frequently?
Intimal FD
GFR equation COCKcroft male?
Female?
GFR = (140-age) X (kg) / (SerumCr X 72)
Male GFR X 0.85
Describe RTA type IV
Causes?
Hyperkalemic, hyporenin, hypoaldosterone
Decreases NH4 excretion and decreased HCO3 production
Analgesic nephropathy, sickle cell, SLE, DM
What drugs can increase serum potassium?
PATTS
Pentamidine Amiloride Triamterene Trimethoprim Spironolactone
Where are the 3 sites located for a post-renal blockage?
Ureteric
Bladder neck
Urethra
What does an elevated BUN mean?
Azotemia
What kind of casts are seen with allergic interstitial nephritis?
White cell (from eosinophils)
Stage 1 of CKD?
kidney damage with normal/increased GFR above 90
IV drug users with bacterial infections are due to what?
Endocarditis
Stage 2 of CKD?
GFR = 60-89
What type of renal artery stenosis shows increased Intravascular volume?
Renin response?
ACE response?
Bilateral and 1 kidney
Varied
Unpredictable
What imaging may be best to visualize the kidneys?
Ultrasound of the abdomen
Drug to treat Pheochromocytoma?
Alpha blocker then beta
What can cause a bladder neck blockage?
Neurogenic bladder BPH Calculi Cancer Blood clot
What is the most common type of fibromuscular dysplasia?
Medial
Describe K, PO4, and uric acid in FSGS?
Ca, albumen, hemoglobin?
What state is patient in?
All high
All low
Metabolic acidosis
What pO2 defines hypoxia?
Less than 60
Drug treatment for hypertrophic cardiomyopathy?
Contraindication?
Beta blockers, CCB
Diuretic, ACEI
What fibromuscular dysplasia occurs in the mid-distal portion of the renal artery?
Perifibromuscular
The combination of HTN and hypokalemia indicate what?
Hyperaldosteronism (Conn’s syndrome)
How is serum creatinine effected in AKI?
Elevated by above 50% or by .5-1 above baseline
A physical exam showing HTN, JVD, pericardial changes, muscle wasting, asterixis, and ecchymoses indicates what?
FSGS
What kind of casts are found in tubular necrosis?
Bloody, brown
What drug to treat chronic renal insufficiency?
Loop diuretic
CCB
What type of renal artery stenosis shows decreased Intravascular volume?
How is renin mediated in this type?
How is BP affected with ACE-I?
Unilateral
Increased
Falls
What has a better response to angioplasty: atherosclerosis or fibromuscular dysplasia?
Which is more progressive?
Fibromuscular dysplasia
Atherosclerosis
How do uremic toxins affect transmembrane voltage?
INC intracellular Na
DEC intracellular K
Inhibition of Ca flux
A dexamethasone suppression test is used for the diagnosis of what?
Cushing’s