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All drugs Flashcards

1
Q

Abciximab

A

Anti-platelet drug - prevents linking of platelets to fibres

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2
Q

Abtacept

A

DMARD - anticytokines - used for arthritis

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3
Q

Acarbose

A

alpha-glucosidase inhibitors - modify glucose breakdown - type 2 diabetes

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4
Q

Acipimox

A

Lipid lowering - lower cholesterol and triglycerides

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5
Q

Adaliumab

A

DMARD - anticytokines - used for arthritis

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6
Q

Alprazolam

A

Benzodiazepines - anxiety and panic disorders

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7
Q

Alteplase

A

Fibrinolytic drugs - stroke - recombinant tissue plasminogen activates or r-tPAs

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8
Q

Amiloride

A

Potassium-sparing diuretics - used in hypertension

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9
Q

Amisulpride

A

Atypical antipsychotic used in schizophrenia

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10
Q

Amitriptyline

A

Tricyclic antidepressants

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11
Q

Amlodipine

A

Dihydropyridines - calcium antagonists - vasodilator used in hypertension

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12
Q

Amorolfine

A

Allylamine antifungal

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13
Q

Amoxicillin

A

beta lactam antibitoic - aminopenicillin - used on gram +ve

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14
Q

Amphotericin B

A

Polyene antifungal that targets ergosterol in plasma membrane

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15
Q

Ampicillin

A

beta lactam antibitoic - aminopenicillin - used on gram +ve

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16
Q

Anistreplase

A

Fibrinolytic drugs - stroke

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17
Q

Aspirin

A

NSAIDs - used for arthritis

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18
Q

Aspirin and Dipyridamole

A

Anti-platelet drug - Aspirin inhibits COX1 preventing thromboxane formation - Dipyridamole inhibits prostaglandin h2 (which makes thromboxane) therefore inhibiting thromboxane formation

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19
Q

Atenolol

A

Beta 1 selective blockers - used in hyptension

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20
Q

Auranofin

A

DMARD - gold compound - used for arthritis

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21
Q

Azathiaprine

A

DMARD - immunosuppressant - used for arthritis

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22
Q

Beclametasone diproprionate

A

Glucocorticoids used as anti-inflammatory drugs in asthma

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23
Q

Bendamustine

A

Cytotoxic - alkylating agent - nitrogen mustards Used in chronic leukaemia

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24
Q

Bendrofluazide

A

Benzothiazide diuretic - used in hypertension

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25
Bevacizumab
Monoclonal antibody - used in chemotherapy Used for colorectal cancer
26
Bicalutamide
Hormone antagonist - androgen antagonist Used in prostate cancer
27
Bleomycin
Cytotoxic antibiotic
28
Budesonide
Glucocorticoids used as anti-inflamatory drugs in asthma
29
Bupropion
Anti-depressant - next generation
30
Buserelin
Hormone - GnRH analogue Used in prostate cancer/advanced breast cancer in premenopausal women
31
Buspirone
Non-benzodiazepine anxiolytics
32
Busulfan
Cytotoxic - alkylating agent Used for leukaemia
33
Canagliflozin
sodium coupled glucose transporters - enhance glucose release - type 2 diabetes
34
Candesartan
Angiotensin II receptor antagonist - lowers blood pressure
35
Capecitabine
Cytotoxic - antimetabolite - pyrimidine analogues
36
Capsaicin
Used for pain in arthritis
37
Captopril
ACE-inhibitor - lowers blood pressure
38
Valporate
Mania and epilepsy - mood stabiliser
39
Carbamazepine
Anti-epileptics used in pain Mania and epilepsy - mood stabiliser
40
Carboplatin
Cytotoxic - alkylating agent - platinum compounds
41
Carmustine
Cytotoxic - alkylating agent - nitrosureas
42
Caspofungin
Antifungal - echinocandins - target fungal cell wall
43
Cefaclor
beta lactam antibitoic - cephslosporin- used on anerobes
44
Cefalexin
beta lactam antibitoic - cephslosporin- used on gram +ve
45
Cefazolin
beta lactam antibitoic - cephslosporin- used on gram +ve
46
Cefepime
beta lactam antibitoic - cephslosporin - used on psuedomonas
47
Cefixime
beta lactam antibitoic - cephslosporin- used on gram ive
48
Cefpodaxime
beta lactam antibitoic - cephslosporin - used on gram -ve
49
Cefuroxime
beta lactam antibitoic - cephslosporin - used on anerobes
50
Chlorambucil
Cytotoxic - alkylating agent - nitrogen mustards
51
Chloraphenicol
Antibiotic which inhibits proteins synthsis - broad spectrum
52
Chloroquine/hydroxychloroquine
DMARD - antimalarial - used for arthritis
53
Chlorothiazide
Benzothiazide diuretic - used in hypertension
54
Chlorpromazine
Antipsychotic - sychosis, schizophrenia, behavioural problems in children
55
Chlorpropamide
Long lasting secretagogues - sulphonylureas - boost insulin release - type 2 diabetes
56
Chlorthalidone
Thiazide-like diuretic - used in hypertension
57
Ciclosporin
DMARD - immunosuppressant - used for arthritis
58
Cinnarizine
Motion sickness, vestibular disorders - h1 antagonist/ antihistamine
59
Ciprofloxacin
Fluoroquinolone antibiotic inhibiting DNA biosynthesis - broad spectrum
60
Cisplatin
Cytotoxic - alkylating agent - platinum compounds
61
Citalopram
SSRI antipressant used in disease pain e.g. HIV, diabetic neuropathy
62
Clopidogrel
Anti-platelet drug - Preventing GPIIa/IIIb receptor expression, Clopidogrel antagonise action of ADP at purigenic receptors
63
Clotrimazole
Imidazole antifungal that targets ergosterol biosynthesis
64
Clozapine
Atypical antipsychotic used in schizophrenia
65
Co-trimoxazole
Antibiotic targetting folic acid synthesis
66
Cyclophosphamide
DMARD - immunosuppressant - used for arthritis Cytotoxic - alkylating agent - nitrogen mustards
67
Cyproterone
Hormone antagonist - androgen antagonist Used in prostate cancer
68
Cytarabine
Cytotoxic - antimetabolite - pyrimidine analogues
69
Dactinomycin
Cytotoxic antibiotic Used in pediatric cancers
70
Dapagliflozin
sodium coupled glucose transporters - enhance glucose release - type 2 diabetes
71
Dasatinib
Protein kinase inhibitor - used for chemotherapy
72
Desipramine
Tricyclic antidepressants
73
Dexamethasone
Glucocorticoid - Inhibit lymphocyte proliferation used to treatment of lymphomas/leukaemias Also vomitting caused by cytotoxics
74
Diazepam
Benzodiazepines - anxiety and seizures
75
Diazoxide
Used to treat hyperinsulinism
76
Diclofenac
NSAIDs - used for arthritis
77
Diethylstilbestrol
Hormone - oestrogen used in chemotherapy
78
Diltiazem
Benzothiazepine - calcium antagonists - vasodilator used in hypertension
79
Docetaxel
Cytotoxic plant derivative - Taxane
80
Doxazosin
Alpha 1 blockers - vasodilator used in hypertension
81
Doxepin
Tricyclic antidepressant
82
Doxorubicin
Cytotoxic antibiotic
83
Duloxetine
SNRI antidepressant used in neuropathic pain
84
Empagliflozin
sodium coupled glucose transporters - enhance glucose release - type 2 diabetes
85
Enalapril
ACE-inhibitor - lowers blood pressure
86
Eprosartan
Angiotensin II receptor antagonist - lowers blood pressure
87
Ertapenem
Beta lactam antibiotic - carbapems - broad spectrum
88
Erythromycin
Macrolide Antibiotic which inhibits proteins synthsis - broad spectrum
89
Estramustine
Cytotoxic - alkylating agent - nitrogen mustards Oestrogen linked so prostate cancer
90
Etenercept
DMARD - anticytokines - used for arthritis
91
Ethinyloestradiol
Hormone - oestrogen used in chemotherapy
92
Etoposide
Cytotoxic plant derivative
93
Exenatide
Secretagogues - incretin mimetics - boost insulin release - type 2 diabetes
94
Ezetimbie
Lipid lowering - lower cholesterol and triglycerides
95
Fenfluramine
SERT inhibitors/5-HT releasers - antidepressants
96
Fibrates
Lipid lowering - lower cholesterol and triglycerides
97
Fluconazole
Triazole antifungal that targets ergosterol biosynthesis
98
Flucytozine
antifungal targets RNA and DNA synthesis
99
Fludarabrine
Cytotoxic - antimetabolite - purine analogues
100
Fluorouracil
Cytotoxic - antimetabolite - pyrimidine analogues
101
Fluoxetine
SSRI antidepressants - depression and ocd
102
Fluphenazine
Antipsychotic - psychosis and schizophrenia
103
Flutamide
Hormone antagonist - androgen antagonist Used in prostate cancer
104
Fluticasone propionate
Glucocorticoids used as anti-inflamatory drugs in asthma
105
Furosemide
Loop diuretics - used in hypertension
106
Gabapentin
Anti-epileptics used in pain
107
Gemcitabine
Cytotoxic - antimetabolite - pyrimidine analogues
108
Gentomycin
Aminoglycoside Antibiotic which inhibits proteins synthsis - broad spectrum
109
Gilbenclamide
Long lasting secretagogues - sulphonylureas - boost insulin release - type 2 diabetes
110
Gliclazide
Short lasting secretagogues - sulphonylureas - boost insulin release - type 2 diabetes
111
Glimepiride
Long lasting secretagogues - sulphonylureas - boost insulin release - type 2 diabetes Insulin sensitizer - Thiazolidinediones/glitazones - type 2 diabetes
112
Glipizide
Long lasting secretagogues - sulphonylureas - boost insulin release - type 2 diabetes
113
Glucagon
Moves towards hyperglycaemia
114
Glucobay
alpha-glucosidase inhibitors - modify glucose breakdown - type 2 diabetes
115
Glucosamine Sulphate
Used for arthritis - major constituent of ECM
116
Goserelin
Hormone - GnRH analogue Used in prostate cancer/advanced breast cancer in premenopausal women
117
Granisetron
Anti sickness - serotonin antagonist
118
GTN
Nitrovasodilator - produces Nitric oxide which increase cGMP in muscle cells which causes muscles to relax leading to vessels dilating
119
Loxapine
Antipsychotic - mood disorders
120
Heparin
Anti-coagulant - activate body’s own anti-clotting molecules antithrombin III
121
Hirudin
Anti-coagulant
122
Hydroclorothiazide
Benzothiazide diuretic - used in hypertension
123
Ibuprofen
NSAIDs - used for arthritis
124
Imantinib
Protein kinase inhibitor - used for chemotherapy - used to treat chronic myeloid leukaemia
125
Imipenem
Beta lactam antibiotic - carbapems - broad spectrum
126
Imipramine
Tricyclic antidepressants
127
Indomethacin
NSAIDs - used for arthritis
128
Infliximab
DMARD - anticytokines - used for arthritis
129
Insulin
Moves towards hypoglycaemia
130
Iodine 131
Internal radiotherapy - thyroid
131
Ipratropium
Muscarinic receptor antagonist - bronchodilator
132
Itraconazole
Triazole antifungal that targets ergosterol biosynthesis
133
Ketamine
Local anaesthetic used in pain particularly in emergency medicine
134
Ketoconazole
Imidazole antifungal that targets ergosterol biosynthesis
135
Lanreotide
Hormone - somatostatin analogue
136
Leflunomide
DMARD - immunosuppressant - used for arthritis
137
Lenograstim
Boosts stem cell production to harvest them and infuse back into patient to combat myelosuppression in chemotherapy
138
Letrozole/exemastine
Hormone antagonist - aromatase inhibitors
139
Leuprorelin
Hormone - GnRH analogue Used in prostate cancer/advanced breast cancer in premenopausal women
140
Levofloxacin
Fluoroquinolone antibiotic inhibiting DNA biosynthesis - broad spectrum
141
Lidocaine
Local anaesthetic used in pain particularly in emergency medicine
142
Liraglutide
Secretagogues - incretin mimetics - boost insulin release - type 2 diabetes
143
Lisinopril
ACE-inhibitor - lowers blood pressure
144
Lithium
Mood stabiliser - acute mania and prophylaxis
145
LMWHs
Anti-coagulant
146
Lomustine
Cytotoxic - alkylating agent - nitrosureas
147
Lorazepam
Anti-anxiety - benzodiazepine
148
Lorazepam
Benzodiazepines - anxiety, status epilepticus, preoperative sedadtion, amnesia
149
Losartan
Angiotensin II receptor antagonist - lowers blood pressure
150
MDMA
SERT inhibitors/5-HT releasers - antidepressants
151
Mechlorethamine
Cytotoxic - alkylating agent - nitrogen mustards
152
Medroxyprogesterone
Hormone - progesterone Used to treat endometrial cancer
153
Megestrol
Hormone - progesterone Used to treat endometrial cancer
154
Meloxicam
NSAIDs - used for arthritis
155
Melphalan
Cytotoxic - alkylating agent - nitrogen mustards
156
Mercaptopurine/Tioguanine
Cytotoxic - antimetabolite - purine analogues Used mainly in leukaemia treatment
157
Meropenem
Beta lactam antibiotic - carbapems - broad spectrum
158
Metformin
Lipid lowering - lower cholesterol and triglycerides
159
Metformin
Insulin sensitizer - biguanideas - type 2 diabetes
160
Methotrexate
Cytotoxic - antimetabolite - folate antagonists
161
Metoclopramide
Anti sickness - dopamine antagonist
162
Metolazone
Thiazide-like diuretic - used in hypertension
163
Metoprolol
Beta 1 selective blockers - used in hyptension
164
Micafungin
Antifungal - echinocandins - target fungal cell wall
165
Miconazole
Imidazole antifungal that targets ergosterol biosynthesis
166
Misoprostol
Synthetic prostaglandin - used for arthritis
167
Mitomycin
Cytotoxic antibiotic
168
Montelucast
Leukotriene receptor antagonist - bronchodilator Prevent exercise induced and aspirin sensitive asthma
169
Moxifloxacin
Fluoroquinolone antibiotic inhibiting DNA biosynthesis - broad spectrum
170
Naloxone
Antagonist - blocks action of opiates - used in treatment of heroin/morphine overdose
171
Naltrexone
Antagonist - blocks action of opiates - used in treatment of heroin/morphine overdose
172
Natalizumab
DMARD - anticytokines - used for arthritis
173
Nateglinide
Short lasting secretagogues - meglitinides - boost insulin release - type 2 diabetes
174
Nedocromil sodium
Cromoglicate used in asthma
175
Nicardipine
Dihydropyridines - calcium antagonists - vasodilator used in hypertension
176
Nicotininic acid
Lipid lowering - lower cholesterol and triglycerides
177
Nifedipine
Dihydropyridines - calcium antagonists - vasodilator used in hypertension
178
Nioltinib
Protein kinase inhibitor - used for chemotherapy
179
Norethisterone
Hormone - progesterone Used to treat endometrial cancer
180
Norfloxacin
Fluoroquinolone antibiotic inhibiting DNA biosynthesis - broad spectrum
181
Nystatin
Polyene antifungal that targets ergosterol in plasma membrane
182
Octreotide
Hormone - somatostatin analogue
183
Ofatumumab
Monoclonal antibody - used in chemotherapy Used for resistant chronic lymphocytic leukaemia
184
Olanzepine
Atypical antipsychotic used in schizophrenia
185
Omacor
Lipid lowering - lower cholesterol and triglycerides
186
Omalizumab
Biologic agent used in asthma
187
Ondansetron
Anti sickness - serotonin antagonist
188
Oxaliplatin
Cytotoxic - alkylating agent - platinum compounds Used to treat colorectal cancer
189
Paclitaxel
Cytotoxic plant derivative - Taxane
190
Paroxetine
SSRI antidepressant used in disease pain e.g. HIV, diabetic neuropathy
191
Paroxetine
SSRI - depression and panic
192
Penicillamine
DMARD - used for arthritis
193
Penicillins
beta lactam antibitoic - used on gram +ve
194
Pentostatin
Cytotoxic - antimetabolite - purine analogues
195
Phenelzine
MAOI - depression and bipolar
196
Phenobarbital
Sedative hypnotic anxiolytic used for insomnia, anxiety, seizures
197
Pioglitazone
Insulin sensitizer - Thiazolidinediones/glitazones - type 2 diabetes
198
Prednisolone
Glucocorticoids used as anti-inflamatory drugs in asthma Glucocorticoids - Inhibit lymphocyte proliferation used to treatment of lymphomas/leukaemias Also used as an anti-inflammatory in asthma
199
Prezosin
Alpha 1 blockers - vasodilator used in hypertension
200
Procarbazine
Cytotoxic - alkylating agent Used to treat hodgkins disease
201
Radium 223
Internal radiation - secondary bone cancer
202
Ramipril
ACE-inhibitor - lowers blood pressure
203
Repaglinide
Short lasting secretagogues - meglitinides - boost insulin release - type 2 diabetes
204
Resins
Lipid lowering - lower cholesterol and triglycerides
205
Reteplase
Fibrinolytic drugs - stroke
206
Rifampicin
Antibiotic inhibiting RNA biosynthesis - TB
207
Risperidone
Atypical antipsychotic used in schizophrenia
208
Rituximab
DMARD - anticytokines - used for arthritis Monoclonal antibody - used in chemotherapy
209
Salbutamol
Short acting beta 2 adrenergic receptor agonist - bronchodilator
210
Salmeterol
Longer acting beta 2 adrenergic receptor agonist - bronchodilator
211
Samarium 153
Internal radiotherapy - Some bone cancers
212
Secobarbital
Sedative hypnotic anxiolytic used for insomnia and acute agitation
213
Sertraline
SSRI - depression and panic disorders
214
Sitagliptin
Secretagogues - incretin mimetics - gliptin - boost insulin release - type 2 diabetes
215
Spironolactone
Potassium-sparing diuretics - used in hypertension
216
Statins
Lipid lowering - lower cholesterol and triglycerides
217
Streptokinase
Fibrinolytic drugs - stroke
218
Streptomycin
Aminoglycoside Antibiotic which inhibits proteins synthsis - broad spectrum
219
Strontium 89
Internal radiotherapy
220
Strontium ranelate
Used for arthritis - Promotes osteoblast differentation/inhibits osteoclast activity which reduces breakdown of bone
221
Sulfasalazine
DMARD - used for arthritis
222
Sulfonamide
Antibiotic targetting folic acid synthesis
223
Tamoxifen (and fluvestrant)
Hormone antagonist - oestrogen antagonist Used in breast cancer
224
Temazepam
Benzodiazepines - short term treatment of insomnia
225
Terazosin
Alpha 1 blockers - vasodilator used in hypertension
226
Terbinafine
Allylamine antifungal
227
Terbutaline
Short acting beta 2 adrenergic receptor agonist - bronchodilator
228
Tetracycline
Antibiotic which inhibits proteins synthsis - broad spectrum
229
Theophylline
Xanthine bronchodilator
230
Rosiglitizone
Insulin sensitizer - Thiazolidinediones/glitazones - type 2 diabetes
231
Thiopental
Sedative hypnotic anxiolytic used for surgery anxiety
232
Tocilizumab
DMARD - anticytokines - used for arthritis
233
Tolbutamide
Short lasting secretagogues - sulphonylureas - boost insulin release - type 2 diabetes
234
Trabectedine
Cytotoxic - alkylating agent Used to treat soft tissue sarcoma and advanced ovarian cancer
235
Tranylcypromine
MAOI - severe depression
236
Trastuzumab
aka herceptin Monoclonal antibody - used in chemotheray
237
Trimethoprim
Antibiotic targetting folic acid synthesis
238
Triptorelin
Hormone - GnRH analogue Used in prostate cancer/advanced breast cancer in premenopausal women
239
Urokinase
Fibrinolytic drugs - stroke
240
Valsartan
Angiotensin II receptor antagonist - lowers blood pressure
241
Vancomycin
Glycopeptide Antibiotic - MRSA
242
Venlafaxine
SNRI antidepressant used in neuropathic pain
243
Venlafaxine
Next generation antidepressant
244
Vidagliptin
Secretagogues - incretin mimetics - gliptin - boost insulin release - type 2 diabetes
245
Voriconazole
Triazole antifungal that targets ergosterol biosynthesis
246
Warfarin
Anti-coagulant - acts on the liver to inhibit the enzyme vitamin k reductase
247
Zafirlukast
Leukotriene receptor antagonist - bronchodilator Prevent exercise induced and aspirin sensitive asthma
248
Zolpidem
Sedative hypnotic anxiolytic used for insomnia
249
Activated charcol
Emetic
250
Apopomorphine
Emetic
251
Aprepitant
Neurokinin 1 antagonist - substance p antagonist - used in chemotherapy induced nausea and vomitting and post operative nausea and vomitting
252
Benzodiazepines
Anticipatory emesis
253
Betahistine hydrochloride
Anti-vertigo drug - H3 agonist
254
Casopitant
Neurokinin 1 antagonist - substance p antagonist - antiemetic
255
Chloropromazine
Dopamine (D2) receptor antagonist - phenothiazine - pregnancy morning sickness
256
Cyclizine
Motion sick - H1 antagonist/anthistamine
257
Domperidone
Migraine and cytotoxic therapy induced emesis, emesis due to emergency hormonal contraception - Dopamine (D2) receptor antagonist
258
Fosaprepitant
Neurokinin 1 antagonist - substance p antagonist - antiemetic
259
Granisetron
Serotonin receptor antagonist - antiemetic
260
Haloperidol
Antipsychotic - psychosis and severe behavioural problems Antiemetic
261
Hyoscine
Motion sickness drug - muscarinic receptor antagonist
262
Marinol
Cannabinoids - antiemetic
263
Maropitant
Neurokinin 1 antagonist - substance p antagonist - motion sickness
264
Metoclopramide
Dopamine (D2) receptor antagonist - antiemetic
265
Nabilone
Cannabinoids - antiemetic - CINV
266
Ondansetron
Drug of choice for chemotherapy induced nausea and vomitting and post operative nausea and vomitting - Serotonin receptor antagonist
267
Palonosetron
Serotonin receptor antagonist - antiemetic
268
Perphenazine
Dopamine (D2) receptor antagonist - phenothiazine - pregnancy morning sickness
269
Prochlorpromazine
Dopamine (D2) receptor antagonist - phenothiazine - pregnancy morning sickness
270
Promethazine
Severe morning sickness in pregnany - h1 antagonist/antihistamine
271
Scopolamine
Motion sickness drug - muscarinic receptor antagonist
272
Syrup of ipecac - ipecacuanha
Emetic
273
Trifluoperazine
Dopamine (D2) receptor antagonist - phenothiazine - pregnancy morning sickness
274
Tropisetron
Serotonin receptor antagonist - antiemetic

My Pharmacology 2nd year drugs (1 decks)

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