All Flashcards
Hand inspection of any exam
Janeway lesions
Non tender eryhtematous macuilpapular lesions (contain bacteria) on palms/pulps of fingers in IE
Hand inspection of any exam
Janeway lesions
Non tender eryhtematous macuilpapular lesions (contain bacteria) on palms/pulps of fingers in IE
Hand inspection of any exam
Janeway lesions
Non tender eryhtematous macuilpapular lesions (contain bacteria) on palms/pulps of fingers in IE
Hand inspection of any exam
Oslers nodes
- Raised tender palpable nodules on the pulps of fingers/toes or thenar/hypothenar eminence.
Assoc w/ IE
Hand inspection of any exam
Oslers nodes
- Raised tender palpable nodules on the pulps of fingers/toes or thenar/hypothenar eminence.
Assoc w/ IE
Hand inspection of any exam
Oslers nodes
- Raised tender palpable nodules on the pulps of fingers/toes or thenar/hypothenar eminence.
Assoc w/ IE
Eye exam of any exam
Xanthelasma - most common xanthoma.
Plane xanthoma usually around the medial canthus of the upper eyelid (but upper and lower eyelids can be affected symmetrically.)
Presents as soft, yellow or orangey macules, papules, or plaques.
Deposits of lipid (often at normal levels)
Assoc w/
- FH
- Type II hyperlipoproteinaemia,
- primary biliary cirrhosis
Eye exam of any exam
Xanthelasma - most common xanthoma.
Plane xanthoma usually around the medial canthus of the upper eyelid (but upper and lower eyelids can be affected symmetrically.)
Presents as soft, yellow or orangey macules, papules, or plaques.
Deposits of lipid (often at normal levels)
Assoc w/
- FH
- Type II hyperlipoproteinaemia,
- primary biliary cirrhosis
Eye exam of any exam
Xanthelasma - most common xanthoma.
Plane xanthoma usually around the medial canthus of the upper eyelid (but upper and lower eyelids can be affected symmetrically.)
Presents as soft, yellow or orangey macules, papules, or plaques.
Deposits of lipid (often at normal levels)
Assoc w/
- FH
- Type II hyperlipoproteinaemia,
- primary biliary cirrhosis
Cardiac
Tendon xanthomas
subcutaneous nodules usu Achilles tendon or over the knuckles.
smooth, firm to palpation, and mobile.
Overlying skin colour is normal. T
Assoc w/ FH (& T2 Hyperlipidaemoa)
Achilles exam of any exam
Tendon xanthomas
subcutaneous nodules usu Achilles tendon or over the knuckles.
smooth, firm to palpation, and mobile.
Overlying skin colour is normal. T
Assoc w/ FH (& T2 Hyperlipidaemoa)
Hand exam of any exam
Tendon xanthomas
subcutaneous nodules usu Achilles tendon or over the knuckles.
smooth, firm to palpation, and mobile.
Overlying skin colour is normal. T
Assoc w/ FH (& T2 Hyperlipidaemoa)
Hand exam of any exam
Tendon xanthomas
subcutaneous nodules usu Achilles tendon or over the knuckles.
smooth, firm to palpation, and mobile.
Overlying skin colour is normal. T
Assoc w/ FH (& T2 Hyperlipidaemoa)
Cardiac
Eruptive Xanthomata
Yellow papules in crops of 2–5 mm w/ red rim over extensor surfaces (elbow, knee, can be buttocks or shoulders, also check inside the mouth).
May be tender and usuy itchy.
Occurs at Trigs >11 mmol/L (any cause but type III hyperlipid)
Cardiac
Eruptive Xanthomata
Yellow papules in crops of 2–5 mm w/ red rim over extensor surfaces (elbow, knee, can be buttocks or shoulders, also check inside the mouth).
May be tender and usuy itchy.
Occurs at Trigs >11 mmol/L (any cause but type III hyperlipid)
Cardiac
Eruptive Xanthomata
Yellow papules in crops of 2–5 mm w/ red rim over extensor surfaces (elbow, knee, can be buttocks or shoulders, also check inside the mouth).
May be tender and usuy itchy.
Occurs at Trigs >11 mmol/L (any cause but type III hyperlipid)
Cardiac
Eruptive Xanthomata
Yellow papules in crops of 2–5 mm w/ red rim over extensor surfaces (elbow, knee, can be buttocks or shoulders, also check inside the mouth).
May be tender and usuy itchy.
Occurs at Trigs >11 mmol/L (any cause but type III hyperlipid)
Mouth exam - any exam
- What is this & associations?
High arched palate in Marfans
assoc w/ AR (aortic root dilatation), MR (MVP)
Mouth exam - any exam
- What is this & causes?
Mucosal petichiae
- IE
- Trauma (vomiting)
- Haem: platelet abnormalities, clotting factor deficiencies
- defects in vascular integrity.
Hand exam of any exam
- What is this & causes?
Splinter haemorrhages
Causes:
1) Local trauma
2) Infective endocarditis
3) Other: Sepsis, Vasculitis, Psoriatic nail disease
Hand exam of any exam
- What is this & causes?
Palmar erythema (vasodilation & should be symmetrical)
- Epo infusion in pulm HTN
- Can be primary (hereditary, idiopathic or PREGNANCY 2⁰ oestregen)
- Liver dis: cirrhosis, Wilson, haemochromatosis
- AI: RA (>60%)
- Endocrine/nutritional: Thyrotoxicosis, DM
- Drug induced (also related to liver functioning)
- Others: smoking, malignancy, COPD, atopic dermatitis, infections
Ix with FBC, LFT, Iron, TSH, Glucose +/- anti CCP, ANA, SSA/SSB, Ceruloplasmin, albumin, (CXR, BM Bx, MRI, CTCAP)
Hand exam of any exam
- What is this & causes?
Koilonychia
Causes
1) Malnutrition/IDA
2) Rheumatic fever
Hand exam of any exam
- What is this & causes?
Leuconychia
Causes
1) Trauma
2) Hypoalbuminaemia
3) Chemo
Hand exam of any exam
- What is this & causes?
Onycholysis
- white discolouration 2* nail bed separating nail plate
Causes
1) Trauma
2) Psoriasis (Linchen Planus, dermatitis)
3) Systemic: Sarcoid, Ank Spond, Cancer, Endocrine
4) Infection (Scabies, dermatophytes)
Neuro exam
(left eye not dilating in dim light)
Horner’s syndrome
- oculasympathetic palsy
- Myosis, Ptosis (tarsal mm), Anhydrosis
IPSILATERAL side:
1st order (Anh+): Central
2nd order (Anh+): preganglionic upto bifurcation ICA/ECA (mediastinal/pancoast/cervical rib)
3rd order (Anh- as nerve to facial sweat glands exits): Carotid artery dissection, otitis media
(also trauma at any point, differentiate with anhidrosis)
Eye exam - unilateral visual loss (monocular)
- where is lesion>??
Pre-chiasm
including retina & optic nerve before optic chiasm on IPSILATERAL side
Can be complete or partial (eg nasal hemianopsia)
Eye exam - binocular outside visual loss
- name
- where is lesion
- causes
Bitemporal hemaniopia
OPTIC CHIASM
1) Pituitary adenoma (acromegaly)
(2 - Meningioma
3 - ACA aneurysm compressing from above)
Eye exam - same (half) VF loss in both eyes
- name
- where is lesion
- aetiology
Homonymous hemianopsia
CONTRALATERAL (if Rt VF loss in both eyes, lesion = LEFT POST-CHIASM optic tract
Macular innvervated by MCA + PCA so can be spared if lesion in occiput in 1 artery.
Otherwise likely optic tract (pre-division)
?RAPD
Eye exam - same (quadrant) VF both eyes
- name
- where is lesion
- aetiology
- other assoc fx
Contralateral optic tract
E - inferior Rt quadrantinopia = Lft parietal
F - superior Rt quadrantinopia = Lft temporal
Cause - mass lesion
Consider - other lobe fx
Temporal: Aphasia, hallucinations
Parietal: Gerstmans (agraphia, acalculia, R/L confusion), contralat neglect,
Eye exam
- name
- where is lesion
- aetiology
Macular sparing homonymous hemianopsia
Occiput lobe
Macular innvervated by MCA + PCA so can be spared in occiput if lesion only on 1 artery
Which nerves open & close eyes?
What conditions will these be abN?
CN7: closes eye (hooks closed)
CN3: opens eye (3 pillars hold open)
Horner’s: oculasympathetic - normal but ptosis
CN3 palsy: closure normal but ptosis
CN7 palsy: weak (can’t wink/smile)
Myopathy/MG: weak closure AND ptosis
Eye exam - rest (can’t look up or in at nose)
- Condition
- Aetiology
- Other tests
Look for ptosis +/- mydriasis (no light reflex) “down & out”
3rd nerve palsy (oculomotor)
Vascular/ischaemia (DM/HTN) + tumour
+ CT-A ?ANEURYSM (Post Com art)
Brainstem lesion: CVA, tumour, demyelination
Sphenoid wing meningioma
Cav sinus lesion/thrombosis
Pupil sparing in ischaemia (DM/HTN) as occurs in middle artery (parasympathetic fibres are outer) -Blown pupil #1 sign of compressive lesion
Eye exam - when looking right
(may be normal with slight head tilt @ rest)
- Condition
- Aetiology
- Other tests
4th nerve / Trochlear palsy
“UP & IN” hypertropia may normalise w/ headtilt
Left eye cant look down to nose on H (Superior oblique impaired)
Vascular, tumour
Congenital & trauma
Eye exam - at rest
- Condition
- Aetiology
- Other tests
6th Nerve palsy / Abducens
Esotropia: eye in at rest, can’t abduct (lateral)
Vascular, tumour
(False localising sign in ICP)
Cavernous sinus lesion
Acoustic neuroma
Neuro/Rheum exam
- sign
- Condition
- Other assoc fx
Shawl sign in Dermatomyositis
photodistributed poikiloderma (look for v-sign)
Heliotrope rash (eyes), nasiolabial fold erythema
Gottrons papules/sign (erythema of knuckles & raised violaceous scaly eruption)
Mechanics hands (periungual erythema, ragged cuticles)
Subcutaneous calcinosis
Prox mm weakenss (ddx myopathy) however neck flexors involved (cf myopathy neck ext)
Neuro/Rheum exam
- sign
- Condition
- Other assoc fx
Shawl sign in Dermatomyositis
- photodistributed poikiloderma (look for v sign)
Heliotrope rash (eyes), nasiolabial fold erythema
Gottrons papules/sign (erythema of knuckles & raised violaceous scaly eruption)
Mechanics hands (periungual erythema, ragged cuticles)
Subcutaneous calcinosis
Prox mm weakenss (ddx myopathy) however neck flexors involved (cf myopathy neck ext)
Neuro/Rheum exam
- sign
- Condition
- Other assoc fx
V-sign in Dermatomyositis
- photodistributed poikiloderma (look for shawl sign)
Heliotrope rash (eyes), nasiolabial fold erythema
Gottrons papules/sign (erythema of knuckles & raised violaceous scaly eruption)
Mechanics hands (periungual erythema, ragged cuticles)
Subcutaneous calcinosis
Prox mm weakenss (ddx myopathy) however neck flexors involved (cf myopathy neck ext)
Neuro/Rheum exam
- sign
- Condition
- Other assoc fx
V-sign in Dermatomyositis
- photodistributed poikiloderma (look for shawl sign)
Heliotrope rash (eyes), nasiolabial fold erythema
Gottrons papules/sign (erythema of knuckles & raised violaceous scaly eruption)
Mechanics hands (periungual erythema, ragged cuticles)
Subcutaneous calcinosis
Prox mm weakenss (ddx myopathy) however neck flexors involved (cf myopathy neck ext)
Neuro/Rheum exam
- sign
- Condition
- Other assoc fx
Gottrons papules/sign
(photosensitive knuckle jt erythema & raised violaceous scaly eruption) - Dermatomyositis
V-sign /shawl sign
Heliotrope rash (eyes), nasiolabial fold erythema
Mechanics hands (periungual erythema, ragged cuticles)
Subcutaneous calcinosis
Prox mm weakenss (ddx myopathy) however neck flexors involved (cf myopathy neck ext)
Neuro exam
- sign
- Condition
- Other assoc fx
Gottrons papules/sign
(photosensitive knuckle jt erythema & raised violaceous scaly eruption) - Dermatomyositis
V-sign /shawl sign
Heliotrope rash (eyes), nasiolabial fold erythema
Mechanics hands (periungual erythema, ragged cuticles)
Subcutaneous calcinosis
Prox mm weakenss (ddx myopathy) however neck flexors involved (cf myopathy neck ext)
Neuro/Hand exam
- sign
- condition & test
- other assoc fx
Mechanics hands in Dermatomyositis
- antisynthetase syndr - anti-Jo1+
- rough, cracked fissures ie. dirty-appearing lines in hands w/ cuticles - periungual erythema, telangiectasias +/- splinter hemorrhages.
Photodistributed rash (V sign, shawl sign)
Heliotrope rash, nasiolabial fold
Gttons papules
Prox mm weakness (flexors - neck, hip, deltoids)
subcut calcinosis
Neuro/Hand exam
- sign
- condition & test
- other assoc fx
Mechanics hands in Dermatomyositis
- antisynthetase syndr - anti-Jo1+
- rough, cracked fissures ie. dirty-appearing lines in hands w/ cuticles - periungual erythema, telangiectasias +/- splinter hemorrhages.
Photodistributed rash (V sign, shawl sign)
Heliotrope rash, nasiolabial fold
Gttons papules
Prox mm weakness (flexors - neck, hip, deltoids)
subcut calcinosis
Neuro/Rheum/Eye exam
- sign
- condition & test
- other assoc fx
Heliotrope rash in Dermatomyositis
Mechanics hands/Gottrons papules
Prox mm weakness
Photodistributed rash (Shawl/V sign)
Subcut calcinosis
Neuro/Rheum/Eye exam
- sign
- condition & test
- other assoc fx
Heliotrope rash in Dermatomyositis
Mechanics hands/Gottrons papules
Prox mm weakness
Photodistributed rash (Shawl/V sign)
Subcut calcinosis
Neuro/Rheum/Eye exam
- sign
- condition
- other assoc fx
Heliotrope rash in Dermatomyositis
Mechanics hands/Gottrons papules
Prox mm weakness
Photodistributed rash (Shawl/V sign)
Subcut calcinosis
Neuro/hand exam
- sign
- conditions
- Antibodies
Subcut calcinosis
Dermatomyositis & scleroderma (CTD overlap)
Overlap: Anti-PM/Scl (or U1-RNP)
Ro52, anti-Ku
DM only: Anti-TIF-gamma & NXP2 have calcinosis
(dSSc = Scl-70, RNA polymerase III,
lSSc anti centromere)
Dermatomyositis: antisynthetase (Jo-1), Anti-MDA5 (ILD, amyopathic but DM)