Alkyl Halides Flashcards
1
Q
Polar Aprotic Solvents
A
- DMF
- DMSO
- DMA
2
Q
Amides are generally __
A
Solids
3
Q
Transition State of SN2 Mechanism
A
- -ve charge
- sp2 hybridized
- 3 permanent sigma
4
Q
Leaving group:
Halogen or Benzoate
A
Halogens are better than benzoates
5
Q
Order of reactivity of:
Benzyl, Allyl, Secondary, Tertiary, Primary
A
Primary > Benzyl > Allyl > Secondary > Tertiary
6
Q
Stability of transition state:
A
-I and -R Group
7
Q
Which type most reactive
A
Alpha - Halpo carbonyl compounds
8
Q
Benzyl Halide follows
1. SN1
or
2. SN2
A
Both SN1 and SN2
9
Q
Order of reactivity of :
1. (bromo methyl) benzene
2. 2-bromo ethyl benzene
3. Tertiary butyl bromide
A
2 > 1> 3
10
Q
Finkelstein Reaction
A
alkyl halide + NaI (in dry acetone) –> CH3CH2I + NaX (PPT)
11
Q
Swartz Reaction
A
AgF, COF2 or SbF5
12
Q
Order of Nucleophilicity for Polar protic:
A
F- < Cl-
13
Q
Order of nucleophilicty of popar aprotic:
A
F- > Cl -
