Aliphatic Compounds Synthetic Routes Flashcards
Alkane to haloalkane
Halogen, UV
Haloalkane to alcohol
NaOH (aq)
Haloalkane to nitrile
CN-, ethanol
Haloalkane to amine
NH3, ethanol
Alcohol to haloalkane
Sodium halide, sulfuric acid
Alcohol to alkene
Sulfuric acid / phosphoric acid, heat
Alcohol to ester
Carboxcylic acid, sulfuric acid
OR
Acid anhydride
Alcohol to carboxcylic acid
potassium dichromate, sulfuric acid, REFLUX
Alcohol to aldehyde
Potassium dichromate, sulfuric acid, DISTILLATION
Alcohol to ketone
Potassium dichromate, sulfuric acid, REFLUX
Aldehyde to alcohol
NaBH4
Aldehyde to hydroxynitrile
NaCN(aq), H+(aq)
Aldehyde to carboxylic acid
Potassium dichromate, sulfuric acid, REFLUX
Carboxylic acid to ester
Alcohol, conc. sulfuric acid
Carboxylic acid to acyl chloride
SOCl2
Acyl chloride to carboxylic acid
H2O
Acyl chloride to ester
Alcohol
Acyl chloride to primary amide
NH3
Acyl chloride to secondary amide
Primary amine
Alkene to alkane
Hydrogen, nickel catalyst
Alkene to haloalkane
Hydrogen halide
Alkene to alcohol
Steam, phosphoric acid
Ester to carboxylic acid
Dilute acid, heat
Ester to carboxylate
OH-, heat
Nitrile to amine
Hydrogen, nickel catalyst
Nitrile to carboxylic acid
Water, HCl, heat
Ketone to alcohol
NaBH4
Ketone to hydroxynitrile
NaCN(aq), H+(aq)
Hydroxynitrile to carboxylic acid
Water, HCl, heat
What is the formula for potassium dichromate?
K2Cr2O7
What can alkanes form?
Haloalkanes
What can haloalkanes form?
ANA
Alcohols
Nitriles
Amines
What can alcohols form?
AKACHE
Alkenes Ketones Aldehydes Carboxylic acids Haloalkanes Esters
What can aldehydes form?
ACH
Alcohols
Carboxylic acids
Hydroxynitriles
What can carboxylic acids form?
Acyl chlorides
Esters
What can acyl chlorides form?
SPEC
Secondary amides
Primary amides
Esters
Carboxylic acids
What can alkenes form?
AHA
Alkanes
Haloalkanes
Alcohols
What can esters form?
CC
Carboxylic acids
Carboxylates
What can nitriles form?
Amines
Carboxylic acids
What can ketones form?
Alcohols
Hydroxynitriles
What can hydroxynitriles form?
Amines
Carboxylic acids