Alcohol Metabolism & Oxidative Stress

Question 1

Briefly explain how the metabolism of alcohol can cause damage to the liver.

Answer 1

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Question 2

Explain why a patient taking the drug disulfiram would experience “Hangover” like symptoms if they subsequently drank alcohol.

Answer 2

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Question 3

Briefly explain how superoxide radicals are produced by mitochondria

Answer 3

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Question 4

List three agents in cells which protect against reactive oxygen species

Answer 4

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Question 5

Briefly explain the relationship between NADPH and glutathione

Answer 5

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Question 6

Define oxidative stress

Answer 6

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Question 7

Briefly explain how a respiratory burst is produced by some leucocytes

Answer 7

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Question 8

Explain how some amino acids can be converted to glucose (glucogenic), some can be converted to ketone bodies (ketogenic) and others can be converted to both glucose and ketone bodies (glucogenic & ketogenic).

Answer 8

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Question 9

Describe the processes that produce ammonia in the body.

Answer 9

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Question 10

Describe in general terms how amino acids are degraded in the
body and list the products of their degradation.

Answer 10

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Question 11

Name two anti-oxidant vitamins

Answer 11

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