Alcohol and Substance Use Disorders Flashcards

1
Q

Excessive sue of alcohol or substance leads to:

When does it become an actual problem?

A

dangerous behaviour (e.g. driving while impaired)

continued use despite persistent problems:
- social
- psychological
- occupational
- health

  • It’s a problem when its jacking you up and you’re still doing it anyway and the impact its having is negative to you.
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2
Q

What is alcohol and substance dependence?

A

Alcohol or substance abuse resulting in:

Tolerance
and/or
Withdrawal

we are looking at dependance when you have tolerance and/or withdrawal. The body is involved. This has something in common with self-harm and eating disorders is that it has a biological and physiological piece and once that kicks it in its really hard to stop.

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3
Q

What is tolerance?

A

Physiological need for ↑ alcohol & substance for
same effects (tolerance is a physiological need so you need more of it to get the effects. )

This results from biochemical changes affecting:
* Rate of metabolism
* Elimination of substance from body

(there are biochemical changes that change your rate of metabolism, the speed at which your body eliminates the substance from the body. )

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4
Q

What is Withdrawal?

A

Physical symptoms that result from stopping use

(when you know you are in withdrawal and you have physical problems as a result like nausea, sweating, tension, headaches, tremors)

Examples:
* Nausea
* Sweating
* Tension
* Headaches
* Tremors

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5
Q

What are the 5 stages of alcohol and substance Abuse?

A
  1. Positive attitude

(Start gerally with a posiotive attitude, you then move into experimentation and move into regular use, then heavy use, and then you get into physiological dependence and/or abuse. )

(when you get into dependence its like you need it to feel ‘normal’ aka you can’t function without it.)

  1. Experimentation
  2. regular use
  3. Heavy use
  4. Physiological dependence/abuse
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6
Q

What are the criteria for the DSM 5 for Alcohol use disorder?

A

Problematic pattern of ETOH use → impairment (ETOH is how the cool people refer to alcohol.) (when you have a problematic pattern that leads to impairment and then you have 2 or more of the following in the next 12 months)

(has to be 2 or more at the same time)

  • 2+ symptoms within 12 months:
  • More ETOH than planned
  • Desire to control use
  • Time spent in ETOH pursuits
  • Craving
  • Use → interpersonal problems
  • Use despite above
  • Activities given up because of use
  • Use in physically dangerous situations
  • Use despite physical/psychological problems due to ETOH
  • Tolerance
  • Withdrawal
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7
Q

What is the WHO criteria for Harmful use of alcohol?

A

Heavy episodic drinking:

(world health organization defines harmful use of alcohol as heavy episodic drinking 6 drinks or more more than once per month.)

  • ≥ 6 drinks
  • ≥ 1x/month

“Alcoholic” no longer used

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8
Q

What is prevalence of harmful drinking patters in undergraduate vs the rest of the population?

A

Harmful drinking patterns:

30% Canadian undergraduates

vs.

17% population

(if you’re an undergrad you’re twice as likely to have a harmul drinking pattern than the rest of the population)

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9
Q

Explain blood alcohol concentration level? what is the medicine wheel diagram for BAC?

A

Blood Alcohol Concentration (BAC)

how intoxicated you get dpeends on a whole bunch of things that are biologically true about your own system. Like being on certain medications can make your blood alcohol concentration higher faster/ If you have more fat you will have higher blood alcohol concentration and females typically have more fat than males.

  • medication
  • sex (fat, retains) vs. water (dilutes)
  • food in the stomach (vs. absorption in small intestine)
  • amount ingested in a period of time.
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10
Q

What are the 4 main categories of short term effects for alcohol and substance use disorder?

A
  • stimulating, then depressant action (sleep/death). It starts as a stimulant and it becomes depressant.
  • interference with complex thought and motor coordination. (it can interfere with complex thought and motor coordination.
  • interactions with neural systems
  • Stimulates GABA receptors
    (tension & motor coordination)
  • Increases 5-HT & DA
    (motivation for pleasure/craving,
    addictive)
  • Inhibits glutamate r
  • effects strongly tied to expectations
  • Aggression
  • Sexual drive

(effects of alcohol are strongly tied to expectations of the substance. You migh have an expectation that you are aggressive etc.)

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11
Q

What are the longterm effects of alcohol and substance abuse disorder?

A
  • malnutrition (vitamin B deficiency = memory loss)
  • cognitive impairment
  • cirrhosis of the liver
  • cardiovascular problems: heart failure, hypertension, stroke, capillary hemorrages
  • reduced immune functioning (increased breast cancer risk)
  • fetal alcohol syndrome
  • psychosis
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12
Q

What is the biological etiology of substance and alcohol use disorders?

A

Genes

What is inherited?
- Alcohol risk
personality

(this is generally your ability to tolerate or metabolize alcohol. If you are more likely to tolerate it, you are more likely to use more and you will be more likely to develop a disorder )

  • Ability to tolerate / metabolize alcohol
  • Motivation for alcohol use
  • Reinforcing effects of the alcohol

(there are some psycho social parts about this

  • if you have an association with alcohol or something not so good you are less likely to develop the disorder/
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13
Q

What is the psychological etiology of substance and drug abuse disorders? According to the diagram she will test us on, who is most at risk?

A

Enhancement – sensation (or novelty) seeking

Coping – stress, tension reduction, reinforcement

Social – expectations of social success

Conformity – perceived benefits outweigh costs

enhancement and coping are the most at risk. If you have high negative affectivity and high neuroticism it is uncomfortablr to feel that way all the time and you may be more likely to develop a disorder for substances that relieve that. Coping is like people get reinforced

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14
Q

What is the sociocultural Etiology of substance abuse disorders?

A

Culture
* Attitudes/use patterns
* Tradition of aggression
* Religion

(religions who are really like no alcohol are less likely to see alcohol abuse. Other religions are like use as much as you want and say sorry on sunda)

(what are the attitudes and use patterns in your cultlure. Culture can be larger culture and sub culture. Is there a tradition of aggression? If you look at among people if you lok at people from certain countries are those countries with more aggressive cultures or passive aggressive Scotland alcohol and likelihhod of aggression is a little different than england’s aggression. England’s aggression is more bitchy or passive aggressive. People who are heavy drinkers from scotland, they are gonna be more likely to fight you when aggressive. The thinky mean people in England are less likely to engage in things physically. )

Family
* Parent use/guidance
* Family/marital problems
* Older siblings

Exposure and learning

Availability of substance (generally how available it is. High availabiliy makes it much more likely that you’re gonna use. Social influences. If you’re around people that are like lets get wasted, you are more likely to.)

Peer/social influences (you can get medications that make you less likely to crave alcohol. )

Media

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15
Q

What is the bio treatment of alcohol and substance abuse?

A

Medications:

  • Black desire to drink (Antabuse, Naltrexone)

lower side effects of withdrawal (valium)

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16
Q

What is the psychological treatment of susbtance and drug abuse disorders?

A

Transtheoretical Model (TTM) - this applies to a lot of things. Basically behaviour you want ot change.

Stages of Change:
1. Pre-contemplation (means I’m just going all in and I’m not even thinking about it. ) no mention of changing behaviour

  1. Contemplation (start ot prepare and be like maybe I should do somethign to not do this etc. )

aware a problem exists but committed to change

  1. Preparation

(intends to take action to change)

  1. Action (actually making changes and starting to do new stuff)

(is sustaining changes and developing new behaviour)

  1. Maintenance (I’m regularly doing stuff I ‘m supposed to be doing.)

(return to old ways)

  1. relapse. (return to old ways)

you don’t want to discount all of the progress they have made with one mistake

often if people just do something once you call it a lapse because you don’t want them to go full swing into it again.

relapse is somethign you want to plan for and expect.

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17
Q

What stage is this person in?

Sarah
16-year-old girl who has been using speed for about two years. She uses speed intravenously, having originally
snorted it for the first 12 months. On assessment, Sarah tells you that she has been trying to cut down on her
speed use and has even had a period of two weeks where she didn’t use it. She appears to be ‘speeding’ when
you meet with her.

A

action and maybe a little relapse

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18
Q

Jian
14-year-old boy who smokes cannabis and tobacco. On assessment of his cannabis use, he states that he can ‘take
it or leave it’. He tends to smoke with friends on the weekend. Jian smokes cigarettes whenever he can afford
them. He also drinks alcohol to the point where he ‘blacks-out’ about once a month.

A

pre-contemplation

19
Q

Shae
17-year-old female who is involved in a Drug Court program. She has a history of poly-drug use and has worked as
a sex worker. Shae has been trying to stay off cocaine and speed. She continues to drink heavily a couple of
times a week and also takes street benzos as she says this helps her to sleep. Shae’s latest urinalysis reveals
cannabis, benzodiazepines and amphetamines. She is pretty worried that she will be taken off the Drug Court
Program and she states she really wants to stay out of trouble.

A

she’s in the action phase but just a little

20
Q

Luis
18-year-old male who has been using heroin for about three years. He smokes heroin on a daily basis and also
takes Valium or Normison if he can’t get any heroin. Luis has been caught breaking and entering on a number
of occasions. His family is very worried about his drug use and the trouble he is i

A

FIGURE IT OUT

21
Q

Psychological treamtent substance use and alcohol abuse?

A

CBT and Behavioural

  • Aversion conditioning (classical conditioning )
  • Skills training (how do you deal with the problems without using. The reason you are using is usually for a lot of different factors)
  • Self-control (will power is not gonna get you out of anything.)
  • Motivational
    enhancement

(see Motivational Interviewing link)

Controlled drinking vs. abstinence

(do you lose everything because you are like I can never go near alcohol again or do you say you can drink once a week.)

22
Q

What is the social treatment for substance abuse and alcohol abuse?

A

Group therapy
* Forced to confront problem
Alcoholics Anonymous (AA)
Environmental intervention
* Halfway houses

(theres like requirements like you can’t have substances where you live and if you do you get kicked out.)

23
Q

What is the treatment efficacy for substance and alcohol abuse?

A

Wide range

looking at people who are in a lot of different circumstances, situations, etc.

Depends on:
* Severity of substance abuse
* Type of treatment

However…
1 Study compared:
* 12-step program
* CBT
* Motivational enhancement therapy

Results: All equally effective

24
Q

Is this abuse or dependence?

Aliyah engages in binge drinking on weekends with her
friends.
Her drinking does not really interfere with work, but her
partner has complained that she drinks too much at times.
She has frequently driven home from a club when her BAC
is over the limit, and she lost her license for 1 year for this
reason.
She often feels terrible the day after partying with friends
and needs most of the day to recover.

25
What is the DSM 5 for substance abuse disorders?
Criteria specific by substance In general, same as alcohol use disorder the criteria are defined by each substnce but in general it is same with alcohol use disorder
26
What are the most common drugs associated with addiction?
Most common * Narcotics (opium) * Sedatives * Stimulants * Anti-anxiety drugs * Pain medication * Hallucinogens
27
What is opium?
some of the narcotics have an opium base like morphine, heroin and codeine Derivatives: * Morphine * Heroin * Coedine
28
Explain what we know about fentanyl?
- synthetic opioid 50-100x as potent as morphine (easy to overdose on) (something to note about overdose, if you are dependent on a substance and you’re like I’m gonna stop I’m gonna stop etc. then when you go back to it and you go back to the same amount you used to take, a lot of people die from that.) Often mixed with heroin, cocaine (without user knowing) (and without the dealer knowing) Responsible for 72% of 2017 overdose deaths in Canada (84% in BC)
29
What are the short term biological effects of substance abuse?
↓ physical pain Relaxation (increases relaxation) ↓ anxiety Euphoria (you can have euphoria) all of this stuff is more at the beginning. You don’t get this as much wen you have tolerance
30
What are the biological effects: long term?
Physiological craving Withdrawal symptoms Physical deterioration * Immune system → organ damage * Consequences of poor health, dangerous behaviour
31
What is the etiology of substance abuse disorders?
Pleasure (could be bio, could be the experience of pleasure (psycho)) * Curiosity (Psycho) * Peer pressure (social) * Stress relief (a little bio a little psycho) * Personal maladjustment * Sociocultural conditions (social)
32
What is the neural basis for addiction?
Binds to opiate receptors → replaces natural endorphins DA theory of addiction (a dopamine theory of addiction says theres some dysfunction from the pathway .) * Addiction = dysfunction of DA reward pathway * All addiction comes from motivation for pleasure Reward deficiency syndrome (we have this deviation in how the pathways are set up and so we are not as rewarded from food or sex or whatever. ) * Addiction = genetic deviation in reward pathway * Folks with genetic deficiency causing less satisfaction from natural rewards (food, sex, etc) more likely to become addicted once exposed
33
What is the neural basis for addiction?
70% other psychological disorders * 50% other substance abuse * 36% history of trauma * Depression * Anxiety * Antisocial personality disorder (this is probably related ot the sensation seeking.)
34
What is the treatment for drug abuse?
Bio: * Methadone * Buprenorphine Psychosocial: Similar to alcohol abuse Narcotics Anonymous (NA) one of the things that seems to get in the way alot is basic ability to survive. A lot of folks who are highly addicted to something and then using a lot can end up just falling to the ground in terms of their access to economics. So their actual lives become much less reinforcing and ou can see people nodding out because they are not as there. And as their lives become less, they want to get away from it more. really hard to kick substance use without shelter.
35
What are the stimulants?
Cocaine Amphetamines (including methamphetamine) Caffeine Nicotine Effects: ↑ alertness ↓ fatigue
36
What are the consequences of amphetamine abuse? Treatment?
Intense fatigue * Psychologically & physically addictive * Brain damage, “amphetamine psychosis” * Suicide, homicide, violence * Withdrawal from drug * Depression (peaks in days, can last months) * GI symptoms
37
What do you know about methamphetamine?
Highly addictive ↑ DA in brain Structural changes in brain Treatment resistance (relapse common) Long-term cognitive effects * Psychosis, paranoia * Learning and memory problems
38
What are the 4 hallucinogens?
LSD Mescaline Psilocybin MDMA (Ecstasy, Molly)
39
What is MDMA?
Hallucinogen & stimulant Chemically similar to methamphetamine Popular party drug
40
What are the short term effects of MDMA? What are the occasional negative effects? long-term (all negative) effects?
Short-term effects * Rush of pleasure * Sense of wellbeing * Depressed mood (for days after use) Occasional negative effects * Psychosis * Anxiety disorders * Death Long-term (all negative) effects * Brain damage (frontal & temporal lobes) * Memory deficits * Hallucinations
41
What are the short term effects of Cannabis? What are the occasional negative effects? long-term (all negative) effects?
Active ingredient: THC Short-term effects * Relaxation, sense of wellbeing, euphoria * Hallucinations * ↑ perceptual acuity Therapeutic effects * ↓ nausea & pain * ↑ appetite & sleep Long-term effects *Psychosis/schizophrenia (if have diathesis) * Memory loss
42
What is a gambling disorder?
Addictive behaviour Similar to substance addiction: * Personality type (sensation seeking) * Maladaptive behaviour * Relationships * Financial * Responsibilities Treatment * Relapse
43