Alcohol and substance use Flashcards
What are the findings of the COMBINE study?
That is, the patient groups who demonstrated the best (statistical) drinking outcomes after 16 weeks of outpatient treatment had received:
- Naltrexone with MM counselling alone (no speciality CBI) or
- Speciality therapy, CBI, with just the placebo pills and MM counselling.
- There was no advantage found in the COMBINE study for adding acamprosate either to MM or to speciality alcohol treatment (CBI)
What is a screening tool for substance use disorders?
- NIDA-modified ASSIST
- AUDIT for alcohol use disorders (WHO)
- DAST-10 for drug abuse screening test
What interventions are done for:
- Pre-contemplation stage
What interventions are done for:
- Contemplation stage
What interventions are done for:
- Preparation stage
What interventions are done for:
- Action stage
What interventions are done for:
- Relapse stage
What is the optimal duration of treatment for substance use disorders?
How quickly does substance-induced psychosis typically resolve?
What can be the effects of VPA in bipolar patients with SUDs?
What is the effect of Lithium in bipolar patients with SUDs?
What are the steps of the metabolism of Alcohol (and the enzymes involved)?
What are the Ottawa-review treatment for Alcohol withdrawal?
What are the 4 domains of the criteria of substance use?
- Impaired control (4)
- Bigger amount / more time than intended
- Persistent desire or unsuccessful efforts to cut down
- A great deal of time spent (obtain/use/recover)
- Craving or a strong desire or urge to use
- Social impairment (3)
- Inability to respond to obligations
- Use despite interpersonal problems
- Giving up social activities
- Risky use
- Use in situations where it is physically dangerous
- Use despite physical / psychological problems caused by the substance
- Pharmacological
- Tolerance
- Withdrawal
When is acamprosate preferred to naltrexone in regards to liver issues?
For medication treatment of alcohol use disorder in patients with:
- acute hepatitis
- liver enzymes ≥3 to 5 times normal
- liver failure
–> we suggest acamprosate rather than naltrexone
What is the basic medication protocol for alcohol withdrawal based on the CIWA?
What is the CIWA protocol for individuals with a history of withdrawal seizures?
What is the CIWA protocol for individuals with a history of who cannot tolerate oral diazepam?
What is the CIWA protocol for individuals with severe liver disease, severe asthma or respiratory failure?
What is the CIWA protocol for individuals with hallucinosis?
