AKI and ICU Neph Flashcards
Which ONE of the following is the BEST marker of renal recovery in AKI-D?
A. Urine output
B. BUN
C. Creatinine
D. Overall Clinical statis
A. Urine output
What are causes of osmotic nephropathy? (5)
- IVIG sucrose
- Hydroxyethyl starch
- Dextran
- Mannitol
- Radiocontrast agents
What is the definition of intraabdominal hypertension?
IAP > 12
What is the definition of intraabdominal compartment syndrome?
IAP > 20
What is the formula for abdominal perfusion pressure, and what is the normal value?
APP = MAP - IAP;
NL is > 50
What are the differentials for AKI in liver disease?
- Hepatorenal syndrome
- Prerenal azotemia (volume depletion)
- ATN
- AIN
- Glomerular dse: IgAN, cryoglobulinemia, MPGN, membranous nephropathy
What is normal access pressure in dialysis?
NL: -50 to -150 mmHg
A very positive access pressure indicates? (3)
- Kinks
- Occlusion of venous return pump
- Erroneous placement in arterial circulation
A very negative access pressure indicates?
Access problem (kink, clot, malposition, very low circulatory volume)
What is normal filter pressure?
50-250 mmHg
What does a high filter pressure indicate?
Clogging of membrane or downstream clotting
How do you calculate transmembrane pressure (TMP)?
TMP = mean filter pressure - effluent pressure
A high TMP (>150 mmHg) indicates?
clogging of the filter (e.g. protein buildup) esp in high inflammatory states
How do you calculate pressure drop?
Pressure drop = prefilter pressure - return pressure
A high pressure drop (>150 mmHg) indicates?
Filter clotting (eg blood clots in the hollow fibers)
What is the relationship between filtration fraction and blood flow rate? Directly or inversely proportional?
Inversely proportional
Therefore, to decrease FF, one must increase the Qb
