AKI Flashcards
What are the stages of IRIS AKI and how are they defined
1: creat < 1.6
* 0.3 or more increase in 48 hours
* oliguria (<1ml/kg/hour) for 6 hours
2: creat 1.6-2.5
* 0.3 or more increase in 48 hours
* oliguria <1 ml/kg/hour for 6 hours
3: creat 2.6-5
- creat 5-10
- creat >10
What are the 5 stages of AKI
- Injury
- inflammation - cellular damage starts
- extension - injury progresses to cell death - biochemical derangements start manifesting
- maintenance - cell death and regeneration at the same time
- repair - improving GFR and tublar function
How is oliguria defined?
< 1 ml/kg/hr
What stain can be used for assessing red blood cell and WBC morphology on urine sediment?
Romanowsky stain
How does renal lypmhosarcoma show on ultrasound?
diffusely thickened cortex
perirenal hypoechoic halo
List 3 methods to measure GFR
inulin clearance
iohexal clearance
renal scintigraphy
endogenous creatinine clearance
How does hyperlactatemia develop in EG toxicity?
artifact
How is fluid overload typically defined?
Bw increase > 10 %
What is the range for insensible losses?
12-29 ml/kg/day
A BUN:Creatinine ratio of > XXX to XXX is indicative of prerenal/fluid-responsive azotemia
greater than 20:1
How is oliguria and anuria defined?
oliguria < 0.5-1 ml/kg/hour
anuria none to negligible amount
What is relative oliguria?
What are the benefits of mannitol administration in AKI?
- protects mitochondrial function
- increases renal blood flow
How does fenoldopam work?
D1 receptor agonist
How is diltiazem suspected to help in AKI?
Ca-channel blocker - renal arteriolar vasodilation
How do you measure urine output with an ultrasound?
measure at different time points and evaluate difference for urine production between those time points.
