AKI Flashcards

1
Q

define an acute kidney injury

A
  • sudden deterioration of kidney function
  • is a spectrum of injuries
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2
Q

how does a prerenal AKI present itself

A
  • caused by reduced blood flow/oxygen
  • hypovolemia and hypovolemic shock
  • decreased CO (MI, HF, carcinogenic shock)
  • decreased peripheral vascular resistance (septic shock, vasodilation)
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3
Q

how does a intrarenal AKI present itself

A
  • damage to kindeys
  • prologned ischemia
  • nephrotoxins
  • hemoglobin or myoglobin
  • medciations (ACE and ARBs - if already on them for long term)
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4
Q

how does a postrenal AKI present itself

A
  • obstruction of UT
  • blocked catheters
  • enlarged prostate
  • tumors
  • non fixed UTI
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5
Q

what are the phases of AKI

A
  • onset phase
  • oliguric phase
  • diuretic phase
  • recovery phase
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6
Q

what is the primary function of the kidneys

A
  • filter waste from circulation
  • maintain fluid and electrolyte and acid base balance
  • excrete wastes
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7
Q

oliguria

A
  • low urine output with stable creatinine
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8
Q

what is the secondary function of the kidneys

A
  • regulates blood pressure
  • bone density
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9
Q

what is non-oliguria

A
  • elevated creatinine with normal urine outpuit
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10
Q

during oliguric phase what electrolyte distrubances will we see

A
  • hyperkalemia
  • hyperphosphatemia (increased production of bone breakdown)
  • hypocalcemia (decreased Vit. D)
  • low sodium
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11
Q

fluid volume overload due to AKI we will see

A
  • JVD
  • edema
  • pleural effusion
  • increased preload
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12
Q

what are risks when in the diuretic phase

A
  • dehydration, hypovolemia and hypotension due to decreased volume (being excreted)
  • hyponatremia and hypokalemia
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13
Q

diagnostics for AKI

A
  • GFR
  • Creatinine
  • BUN
  • HCO3 levels
  • Renal ultrasound
  • Renal CT
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14
Q

what does GFR show

A
  • decrease in cardiac output
  • due to either hypotension or hypovolemia
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15
Q

creatinine levels indicates

A
  • GFR fails - not filtered so stays in
  • muscle break down
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16
Q

BUN levels show

A
  • late indicator of kidney injury
  • medications, high protein diets, trauma, and infection affect it
17
Q

what treatment do we do if not enough CO or perfusion

A
  • IV fluids (crystalloids isotonic)
  • diuretics - if not oliguric
18
Q

what to do if experiencing hyperkalemia

A
  • stablilize myocardium - ECG stat and give calcium gluconate IV if changes happen
  • IV insulin and IV glucose (shift K into cells)
  • potassium removal (kayexalate)
19
Q

what is dialysis

A
  • removal of wastes and fluid form blood
20
Q

hemodialysis

A
  • blood pumped through filter
  • removes urea and uric acid
  • balances electrolytes
  • 3x a week
  • hypotension is a complication
21
Q

peritoneal dialysis

A
  • used for non renal injuries
  • removal done through peritoneal fluid
  • night time
  • many complications - abdominal pain, respiratory, hypotension
22
Q

how do you diagnose the cause:

A

S: Sepsis and hypoperfusion (prerenal)
T: toxicity
O: obstruction (post renal)
P: Primary renal (intrarenal)