Airways and Respiratory Flashcards
What are the causes of bronciolitis?
Respiratory syncytial Virus<br></br>human metapneumovirus, <br></br>adenovirus, <br></br>influenza, <br></br>rhinovirus and <br></br>parainfluenza virus
Apnea risk factors in bronchiolitis
prematurity, <br></br>less than 3 months old, <br></br>previous episode of apnea, <br></br>underlying cardiorespiratory disease, immunodeficiency
Admission criteria in bronchiolitis:
<ul> <li>prematurity,</li> <li>persistent tachypnea or work of breathing,</li> <li>dehydration,</li> <li>Need for oxygen supplementation,</li> <li>apnea (witnessed or risk factors, even if well appearing)</li> </ul>
Complications of cystic fibrosis
<p>Acute respiratory exacerbations<br></br>Pneumonia<br></br>PneumoTx<br></br>Chronic inflammation leading to bronchiectasis<br></br>Cor pulmonale<br></br>Meconium ileus<br></br>Pancreatic insuff (DM, FTT, pancreatitis, malabsorption)</p>
Initial ventilator setting for intubated asthmatic patient:
“<ul><li>Respiratory rate low (6-8/min) to start</li><li>Small tidal volumes (6ml/kg of ideal body weight)</li><li>Fast inspiratory flow rate (≥ 100L/min) to allow a long expiratory time (I:E >1:4 ie inspiratory to expiratory ratio of 1:4 or more)</li><li>FiO2 100% initially then titrated down to keep sats > 90%</li><li>Minimal or no PEEP (≤5)</li><li>Agoal of a plateau pressure of less than 30mmHg. If the plateau pressure is too high, decreasing the respiratory rate<br></br></li><li><img></img><br></br></li></ul>”
Severe asthma Mx
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What are the causes of atypical pneumonia
<p>–<em>Legionella pneumophila</em></p>
<p>–<em>Mycoplasma pneumoniae</em></p>
<p>–<em>Chlamydia pneumoniae</em></p>
<p>–<em>Chlamydia </em><em>psittaci</em></p>
<p>–Fungal pneumonia <em>(Candida, Aspergillus, Cryptococcus, </em>etc<em>)</em></p>
<p>-Viral pneumonia<em> (HSV, CMV, RSV, EBV, VZV, </em>etc<em>)</em></p>
<p>When should you consider testing for atypical causes of pneumonia?</p>
<p>–Severe pneumonia</p>
<p>–Known outbreak (ie. Legionella)</p>
<p>–Definite findings of other non-pulmonary site of infection (chlamydia, VZV, etc)</p>
<p>–Significant immunosuppression</p>
<p>Match the etiologic agent with its typical chest radiograph appearance</p>
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CURB-65
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<p>According to North American Guidelines, list 2 potential classes of oral antibiotics that could be appropriate as first line outpatient treatment for pneumonia</p>
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<p>What are the <strong>most</strong> important MRSA/Pseudomonas risk factors when considering empiric coverage?</p>
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<p>Name 3 names or classes of antibiotics to cover pseudomonal respiratory infections</p>
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<p>Name 3 names or classes of antibiotics to cover MRSA respiratory infections</p>
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<ul> <li>Distinguish between aspiration pneumonitis and aspiration pneumonia</li> </ul>
<p>–Aspiration pneumonitis = acute reaction to chemical insult</p>
<p>–Aspiration pneumonia = occurs 24-72h after initial aspiration event, secondary bacterial infection</p>
<p>aspiration pneumonia. List 2 oral and 2 parenteral medication regimes for this condition</p>
<p>–Requires oral anaerobic coverage:</p>
<ul> <li>Amoxicillin + Clavulin</li> <li>Amoxicillin + Metronidazole</li> <li>Clindamycin</li> <li>Moxifloxacin OR Levofloxacin +/- Metronidazole</li> <li>Ceftriaxone + Metronidazole</li> <li>Piperacillin/Tazobactam</li> <li>Carbapenem</li> </ul>
DDx of fever + hemoptysis
<ul> <li>Infection <ul> <li>Pneumonia</li> <li>TB</li> <li>Bronchitis</li> </ul> </li> <li>Vascular <ul> <li>PE</li> <li>AVM</li> <li>Pulm hge</li> </ul> </li> <li>Malignancy</li> <li>Bronchiectasis</li> <li>Granulomatous dis</li> </ul>
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<p>Risk Factors for TB Infection</p>
<ul> <li>(Travel/work in endemic area)</li> <li>Contact withtuberculosis positive individual</li> <li>Immunocompromised (esp. HIV)</li> <li>Elderly</li> <li>Nursing home resident</li> <li>Alcoholism</li> <li>Illicit drug users</li> <li>Prisoner resident/staff</li> <li>Health care worker</li> <li>Homeless shelters</li> <li>First nation reserves</li> </ul>
Rx of TB
<p>RIPE</p>
<ul> <li>Rifampin</li> <li>Isoniazide</li> <li>Ethambutol</li> <li>Pyrazinamide</li> </ul>
SE of TB meds
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What is the definition of Massive hemoptysis?
<p>–>500ml over 24h</p>
<p>–>100ml over 1hr</p>
<p>–Hemoptysis associated with hemodynamic instability</p>
<p>–Clinically: <em>streaking vs. vials</em> vs. <em>frank </em>bright red blood</p>
<ul> <li>What temporizing measure can be considered before intubation/ while awaiting definitive management of massive hemoptysis?</li> </ul>
Nebulized TXA
<p>Light’s Criteria of pleural effusion</p>
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Transudative vs Exudative pl effusion
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Initial Mx of AECOPD
iv access<br></br>O2 +/- NIPPV<br></br>Ventolin/atrovent
DDX of acute SOB
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Mised Ix for acute SOB
Trop<br></br>D-Dimer<br></br>BNP<br></br>ABG/VBG<br></br>Lactate<br></br>CXR<br></br>ECG
“Interpret this CXR<br></br><img></img>”
<p>Hyper-expansion, flattening of hemi-diaphragms</p>
<p>Chronic COPD</p>
<p>Absence of consolidation</p>