Air pollution Flashcards
London-Great smog
- smoke particles, carbon dioxide, hydrochloric acid, fluorine, sulphur dioxide
- contributed to 4000 to 12000 deaths
- creation of air pollution control legislation
Air pollution
- number one cause of early death
- automobile exhaust is largest contributor in North America
- outsourcing manufacturing
smog
four main pollutants:
-particulate matter, ozone, nitric oxides, sulphur oxides
coal burning compounds released to the air
-sulfur dioxide, nitrogen oxides, particulate matter, mercury
sulfur dioxide
- form small acidic particulates
- absorbed into human lungs and passed into the blood stream
- acid rain
- emission controls=smokestack scrubbers
nitrogen oxides
- ground level ozone or smog
- burn lung tissue, exacerbate asthma, chronic respiratory diseases
- emission controls=catalytic reduction technology
particulate matter
- soot or fly ash
- chronic bronchitis, aggravated asthma, premature death, haze
- emission controls=baghouses
mercury
- fish contaminate
- emission controls=carbon injection combined with baghouses
Acute lung injury
- Oxidative burden
- Airway reactivity
- Pulmonary edema
- Cell proliferation
oxidative burden
- ozone, NO2, tobacco smoke, lung immune system cells generate ROS
- Cause cellular damage
airway reactivity
- trigger bronchoconstriction, limiting oxygen uptake
- problematic with asthma
pulmonary edema
- cellular damage causes leaking of fluid into alveolar spaces
- less O2 exchange can trigger heart attacks
cell proliferation
- type II epithelial cells proliferate and eventually transform into type I cells
- excessive cell division lead to an increase in mutations
Chronic lung injury
- COPD (chronic obstructive pulmonary disorder)
- fibrosis
- asthma
- cancer
COPD
- emphysema=destruction of the alveolar sacs
- bronchitis=constant inflammation of bronchi and excessive mucous deposition
- increase in lung infections
fibrosis
- inflammation increased deposition of collagen in damaged lungs
- lungs less elastic and depresses oxygen exchange
asthma
-recurrent bronchoconstriction
cancer
- direct DNA mutations from oxidative damage
- indirect DNA mutations from excessive cell division to replace damaged cells
airborne particulate matter
- heterogeneous calls of compounds
- classified according to size
- toxicants can absorb onto the surface of particles
Particulate matter and other pollutants causes
- lung irritation-increase permeability
- susceptibility to viral and bacterial pathogens-pneumonia in vulnerable persons
- aggravates the severity of chronic lung diseases-loss of airway function
- inflammation-release of chemicals that impact heart function
- changes in blood chemistry-clots and heart attacks
Ozone
- hardest pollutant to control
- most acutely toxic
- NO2 released in morning traffic undergoes photolysis and creates ozone
- directly oxidize cellular components
- emergency respiratory admissions at hospital related to ozone exposure
nitrogen dioxide pollution
- automobile exhaust
- source of surface ozone
- lung irritant
- NO2 hydrolyzes to nitrous and nitric acid cause chemical pneumonitis and pulmonary edema
- acute toxicity
- comes from fresh silage, agriculture
- coughing, shortness of breath, type I cell damage, pulmonary edema, death
sulfur dioxide pollution
- emitted from vehicles
- irritant of respiratory tract
- hydrated to form sulphurous acid
- causes bronchoconstriciton and reduced airway flow
- bad for asthmatics
- absorbed primarily in nasal passages and bronchi
acid rain
- S is oxidized by O2 during the burning process to make SO2
- SO2 can be oxidized by O (produced by UV light and O2)
- SO3 is readily hydrated to make H2SO4
-Asbestos
- silicate material in fibre form
- insulation, fire retardant materials
- consumed by lung macrophages, asbestos fibres can not leave the lung
- inflammation response, high turnover of alveolar cells
- long lag time to cancer from exposure
- cancer=mesothelioma
- banned in Canada but still exported
Smoking
- thousands of toxicants
- particulate matter
- arsenic
- bezene
- cadmium
- cause of lung and throat cancer
Government regulation of air pollutants
- particulate matter annual and 24-hour, and ozone
- guidelines not enforced limits
air pollution point sources in Manitoba
- hydroelectric capacity generated from hydro
- only two fossil fuel generating plants
- two major mining smelters (no longer functioning)