AHMI Et ITP Flashcards

1
Q

AHMI type d’hypersens

A

Type 2
Hémolyse intra vasculaire (Ac GR) ou phagocytose (hémolyse extra vasc

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2
Q

SC AHMI

A

tachycardie et tachypnee
Urine foncée
Ictere
Fièvre
+- souffle
Splénomégalie

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3
Q

Dx AHMI

A

Agglutination (saline ou coombs)
Savoir si prim ou sec:
Hemato + frottis = regenerative? Virage a G? Parasite?
Bioch: foie PT/PTT

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4
Q

Tx AHMI

A

Transfusion sang GR slm
Pred 2mg/kg 4-6 sem
Si trop d’effets sec: ajout azathioprine ou cyclosporine
Puis diminuer pred 25% aux 4 sem si HT ok
Anticoagulants (CIVD!!!)
Antibio car immunosup

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5
Q

Quelle est la cause #1 de mortalité lors de AHMI*

A

CIVD donner anticoag!

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6
Q

Px AHMI

A

Réservé
Agglutination, thrombocytopenie, élévation de pls paramètres

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7
Q

Qu’est ce que l’ITP?

A

Thrombocytopenie a med immun

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8
Q

ITP type de hypersens

A

Type 2
Ac a la surface des plaquettes = lyse via complément ou phagocytose

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9
Q

SC ITP

A

Petechies, ecchymoses
Thrombopénie frottis
PT et PTT ok

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10
Q

Tx ITP

A

Transfusion plasma riche en plaquettes
Concentré de plaquettes
Si saignement SNC ou poumons ou chx mais ne dure que Qques heures…

Immunosup
Antibios
Vincristine : fragmente megacaryocytes en plaquettes

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