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Agitation Flashcards

1
Q

Carbamazepine

A 
Oral contraceptive
Lovastatin
Meperidine
Morphine
Nifedipine
Oxycodone
Trazodone
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2
Q

Divalproex

A

Lamotrigine

Lorazepam

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3
Q

Trazodone

A

Priapism

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4
Q

TCA

A

Anticholinergic effect
Monitoring require
ECG abnormalities (caution in patient with cardiovascular disease and arrhythmias)

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5
Q

Mirtazepine

A

Weight gain

Sedation

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6
Q

Maoi (phenelzine）

A

Edema

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7
Q

Lithium

A 
Interac with
NSAID
Ace
Arb
Thiazide diuretic 
Require stable salt and caffeine intake
S/E:
GI upset and polyuria
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8
Q

Atypical

A

Side effect
Extrapyramid ( reduce in 2nd generation) unless use as high dose
GI
Heart problems (stroke) ( on quetiapine, risperidone/olanzapine)
Weight gain ( issue for 2 nd generation )
-due to abnormality glucose
-hyperlipidemia ( clozapine and olanzapine) Cl with diabetes
-high triglyceride ( Quetiapine)

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9
Q

Ssri

A

S/e
GI cns
Sexual dysfunction

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10
Q

MAOI

A

Edema

Can induce hypertension

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11
Q

Divalproex

A 
Weight gain (antiepileptic)
Polycystic ovary syndrome 
Hyperammonemia
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12
Q

Clozapine (atypical)

A

Require regular blood monitor

Cardiovascular side effect

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13
Q

Antipsychotic ( 1 st generation)

A

NMS ( for 1 and 2nd generation ) cause muscle restless ( might damage the muscle)( autonomic dysfunction which is irregulars HR,etc)
Sedation and cognitive (problem with remembering認知障礙
( anticholingeric and anticonvulsant) worse the cognitive
TD ( dyskinesia) uncontrolled movement ( with initial treatment)
Cardiovascular problem
Endocrine and sexual problem
Hyperprolactinemia ( high prolactin ) like milk product when not pregnant
-Fertility problem
-Irregular menstrual

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14
Q

Clonazepam and diazepam

A

Long acting

Could use for switching from benzo withdrawal

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15
Q

Benzo

A

Short acting ( give greater risk of fall especially in elderly)
Better with the lorazepam for elderly
Flurazepam and nitrazepam ( give hangover)
Triazolam ( only help to fall asleep but not to maintenance the sleep and cause memory loss ( amnesia) not suitable for elderly )
Oxazepam (take 60-90 mins before slow absorption good for maintenance)
If use for long term( heart problem like hypertension or seizure might occur)

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16
Q

Zopliclone

A

Effect the taste

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17
Q

L-tryptophan

A

S/E:Serotonin syndrome

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18
Q

MAOI
Antidepressant (SSRI,SNRI,TCA)
Opioid

A

Could give s/c serontonin syndrome

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19
Q

Clonidine

A

Alpha adrenergic anoints
Treat for hypertension,ADHD,withdrawal symptoms from alcohol or opioid)
Can treat for smoking cessation for those who have hypertension ( anything that treat for heart can give hypotension as s/E)
CI with TCA.
Uncommon side effect: memory problem

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20
Q

Trazodone

A 
Antidepressant
Serotonin agonist
( can be use for insomnia)
Can use to lower BP and HR
S/E: priapism
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21
Q

Bupropion ( Wellbutrin /Zyban)

A

Noephirphine and dopamine reuptake inhibitor?
S/E:insomnia difficult concentrate
Eating disorder/ seizure

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22
Q

Buspirone

A

Azapirones
Switch for benzo
(Those couldn’t take benzo for the general anxiety disorder)

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23
Q

Pregabalin and gabapentin

A

Antiepileptic
S/E:unsteady gait(walk)
Edema
For not general seizure

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24
Q

Atomoxetine

A

Norepinephrine reuptake inhibitor

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25
SSRI
Sexual dysfunction | GI and CNS effect
26
Thiamine
For alcohol withdrawal | Eating disorder to prevent wernick of
27
Ergotamine
Vasoconstriction
28
Tristan’s
Chest discomfort Nasal formulation S/E: taste disturbance Do not use if any cardiac symptoms\
29
Flunarizine ( CCB)
S/E: Depression EPS Constipation
30
Phenytoin
Antiepileptic Increase body hair Gingival hyperplasia ( over growth of gum)
31
Antiemetic
EPS (Parkinson’s like symptoms ) | CI:alcohol
32
Beta blocker
Depression | CI:antacid , contraindicate with pulmonary and cardiac disease
33
NSAID
CI: antihypertensive
34
Prednisone
CI：diabetes ,peptic ulcer
35
Quinine sulfate
Visual impaire ,fatal thrombocytopenia
36
Dopamine agonists
``` Daytime sleepiness (attack of sleep),heart problem Personality change ```
37
bromocriptine
Cardiac and Pulmonary fibrosis
38
Pergolide
Cardiac valve fibrosis
39
amantidine
Leg edema
40
Antiepileptic
``` Hypersensitive syndrome (monitor cbc and liver serum) Watch out for blood and liver ```
41
Iminostibene derivatives
Neutropenia Hyponatremia CI: contraceptive May worse absence seizure
42
Ethosuximide ( suinimide derivative)
For absence seizure only
43
Vigabatrin
Vision problem
44
Ciprofloxacin
Photosensitive | Abdominal pain
45
Aminoglycoside (eye drop)
Conjunctivitis
46
Carbonic anhydride inhibitor | brinzolamide>dorzolamide>acetazolamide and methazolamide
Should not use in patient with sulfonamide allergy | S/E: GI and CNS ,renal and paresthesia ( hand) mainly for acetazolamide and methazolamide ( for emergency use only)
47
antihistamine
caution in glaucoma patient due to anticholingeric effect
48
synthroid
interaction with iron supplement ( decrease absorption of T4)
49
Sibutramine
Satiety enhancer SNRI Increase heart rate and BP
50
Orlistat
Fecal urgency | CI ：decreased absorption of soluble vitamins （take 2 hrs apart）
51
Rimonabant
Block CB-1 receptor Endocannabonid system Suppress food intake S/E depression and n&v
52
Statin
S/E:Muscle pain | Liver toxicity
53
Niacin
Side effect flushing （red face） | Gout
54
ACE
S/E: dry cough , angioedema (ARB)
55
NSAID , corticosteroid,stimulant
Can indue hypertension
56
Drink
9 per week for women | 14 per week for men
57
Beta blocker
Use for patient less than 60 Ineffective use as cardiovascular prevention for smoker Avoid in sever peripheral arterial disease Avoid in asthma patient Taper the dose before D/C S/E: depression, heart failure
58
CCB Diuretic ARB
Use for patient over 60
59
ACE
1st line for diabetes, history of MI, heart failure, kidney disease Teratogenic for pregnancy ( ARB) Not recommend as initial therapy for black people S/E: dry cough ( drug that end with ‘’pril’’ like ramipril) Treat patient with renal dysfunction
60
Loop diuretic
Can use for renal impairment ( serum creatine greater than 150)
61
Diabetes with nephropathy
Use ACE or ARB
62
Heart failure
Avoid nondihydropyridine CCB ( diltiazem ,verapamil)
63
Patient with bilateral or unilateral renal artery stenosis disease
Avoid ACE/ARB
64
Diuretic
S/E: hypotension,hypokalemia, muscle cramp | Ineffective in those with ClCr less than 30
65
Metolazone
Diuretic ( effective in moderate to sever renal dysfunction)
66
Beta blocker nonselective
Nadolol Timolol Propranlol
67
Beta blocker selective B1
Metoprolol Atenolol Bisoprolol
68
Beta blocker with aplpha blocking activity
Labetalol | S/E: edema
69
ARB
Drug end with ‘’sartan’’ like candesartan Cause Renal dysfunction an hyperkalemia （same as ACE) Require close monitoring of creatine,potassium
70
CCB( dihydropyridine)
Edema | Not recommend for STEMI patient
71
Cholesterol greater than 3.5
Treat with statin therapy
72
Ticlopidine
Antiplalet | ( last choice) a lot of S/E :neutropenia ,thrombocytopenia,thrombotic
73
Nitrate
S/E: headache,syncope ( faint) there for sit when taking the sublingual tab
74
Levocabastin
Nasal antihistamine
75
Ipratropium ( atrovent)
Antimuscarine short acting Broncho Muscle dilation and decrease mucus secretion Treat for COPD / running nose
76
Oxybutin
Selective M3 receptor | Primary receptor in bladder ( help to hold the bladder for urine）
77
SABA ( fenoterol,salbutamol,terbutaline)
S/E: tachycardia,palpitations | High dose may lead to hypokalemia and tremor
78
Singular
S/E: headache
79
Theophylline
Serum level should be measure ( between 55-85) Drug level increase if patient stop smoking S/E:Abdominal cramps
80
Ketotifen
Adjunctive anti-inflammatory
81
Tetracycline
Cyclin ( think about the bicycle ） Contraception pills become less effective Also empty stomach and 30 min sit after taking, no calcium
82
Oxygen (55-59)
Give oxygen therapy ….resting oxygen should be 65-80
83
Cephalosporin
S/E: GI intolenrance
84
Metronidazole
Steven Johnson syndrome ( red skin and peeling) | Taste and urine discolour
85
Sulfonamide ( stop folic acid synthesis) sun,high urin ( very dry) so drink a lot of water and folic acid daily Tetracycline ( stop protein synthesis) Fluroquinolone ( for UTI and peunomia)
86
Beta blocker
Use for general all patient with NSTEMI
87
Potassium sparing
Don’t use if creatine serum greater than 221 Potassium greater than 5 Creatine clearance less than 30

Drug Interaction (1 decks)

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