Aging and Cardiopulmonary disease (Mod 3) Flashcards

1
Q

What are general considerations for the Geriatric population?

A

Increasing vulnerability to accidents and disease

  • age increases susceptibility to disease
  • Hard to differentiate between normal aging and pathological process
  • Longer recovery periods
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2
Q

What are the general effects of ageing?(10)

A
  • Renal function decline
  • Falls/Injury
  • Bone mass loss
  • Sensory impairment
  • Cognitive decline
  • Hearing loss
  • Polypharmacy
  • Loss of muscle mass and strength
  • Decreased immunity
  • Psychosocial implications
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3
Q

What can occur with renal function decline with age?

A
  • Drugs don’t clear out as fast
  • Decreased U/O
  • Electrolyte imbalance
  • May need dialysis after treatments
  • More susceptible to Dehydration
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4
Q

General anatomical/physiological changes to the respiratory system as a result of ageing?

A
  • Increased airway reactivity
  • Increased risk of pharyngeal collapse; OSA
  • Decreased ciliary number and activity
  • Diminished airway reflexes
  • Dysphagia
  • Cervical spine stenosis/stiffness
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5
Q

What changes can be expected with age?

A
  • Calcification of cartilage in tracheal walls and bronchi
  • Functional changes in airway receptors
  • Drug admin may need to be adjusted
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6
Q

What altercations can be expected to the Alveoli with a age?

A

Number of alveoli remain unchanged

  • Alveolar ducts and alveoli wider, shallower
  • Decrease gas exchange surface area
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7
Q

How are the functions of respiratory muscles affected by aging?

A

Decreased total muscle mass and muscle strength (muscle atrophy)

  • Decreased strength of cough
  • Decreased MIP
  • Decreased proportion of fast twitch fibres
  • Intercostal/Diaphragmatic muscle atrophy (EMG activity reduced by 50%)
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8
Q

How is the Thoracic cage affected by aging?

  • Slide 9
A
  • Calcification of costal ligaments
  • Kyphosis
  • Decreased range of motion for thoracic rib articulations
  • Thoracic vertebral height loss
  • Increased anteroposterior chest diameter
  • Decreased elasticity of intercostal muscles
  • Flattened curvature of the diaphragm
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9
Q

How is lung function affected by aging alterations?

A
  • Decreased chest wall compliance; increase in RV
  • Recall; chest wall compliance +.Lung = compliance
  • Increased AC membrane thickness; DLCO decline
  • Senile emphysema?
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10
Q

What are the affects of Senile emphysema?

A
  • Degeneration of elastic fibres, enlargement of air spaces
  • Increase of closing capacity -> decreases max. insp. Flow-air trapping
  • FEV1 and FVC both decrease (FEV1/FVC only to a small degree)
  • TLC unaffected
  • RV and FRV increase-decreased VC
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11
Q

Why does RV increase with ageing?

A

Decreased chest wall compliance increases RV and FRV but decreases VC because of senile emphysema

  • Degeneration of elastic fibers enlarges air spaces
  • Increase of closing capacity decreases max insp. = flow air trapping
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12
Q

How is Ventilatory response with ageing?

A
  • Increased shunt (senile emphysema)
  • Anatomic dead space increases Vd/Vt
  • PaO2 declines w/age, P(A-a)O2 increases at rest
  • Diminished ventilatory response to PaO2 and PaCo2
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13
Q

How is immunity affected with ageing?

A
  • Increased immunoglobulin content
  • Decreased alveolar macrophage population
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14
Q

How is the Cardiovascular system affected by ageing?

A
  • Heart wall thickness increases (especially L ventricle)
  • Heart valve thickening and calcification (Mitral, Aortic)
  • Arterial collagen content increases-stiffening, high systolic pressure
  • Postural hypotension
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15
Q

Polypharmacy issue with aging

A

patient swallow reflex gets dulled as they get older so they are more vulnerable to aspirations

  • many come in with micro aspirations, and get repeated pneumonia which is a first sign that they’re micoaspirating
  • Decreased immunity, recommend they get more vaccines than other populations
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16
Q

Why does aging reduce responsiveness to drugs like Ventolin

A

Alveolar ducts and alveoli are wider and shallower = decreased gas exchange surface area

  • leads to decreased DLCO
  • secondary cause is because the AC membrane gets thicker with age
17
Q

Implications of decreased total muscle mass in aging?

A

Decreased muscle strength =

  • Decreased strength of cough and
  • Decreased MIP
18
Q

Implications of a stiffer thorax in geriatric patients (aging)

A

We get shorter as we age, air trapping is more likely to occur due to decreased chest wall compliance = higher WOB

  • Decreased thoracic compliance and increased lung compliance
  • resting SpO2 also drops with age
19
Q

Why does the risk of air trapping increase with age?

A

Inability to empty lungs on exhalation due to stiffer thorax

20
Q

Ventilatory response to aging?

A

Increase shunt due to senile emphysema

  • anatomic dead space (vd/vt) increases
  • PaO2 declines with age, P(A-a) increases at rest
  • Diminished ventilatory response to PaO2 and PaCO2 (They decompensate fast)
21
Q

Characteristics of senile emphysema?

A

Degeneration of elastic fibres, enlargement of air spaces

  • Increase of closing capacity, decreases max. insp. Flow-air trapping
  • FEV1 and FVC both decrease (FEV1/FVC only to a small degree)
  • TLC unaffected
  • RV and FRV increase-decreased VC
22
Q

Why do geriatric populations have slower recovery periods?

A

Since they have a higher immunoglobin (iGe) content, which is normally lower. It means they are highly reactive to allergens.

  • A highly reactive immune system = increased inflammation in the lungs and degenerate changes like COPD
  • Leads to chronic inflammatory process
  • Not only that, Cilia are not doing their job = weak cough and gag meaning they can’t clear junk out.
23
Q

Why do geriatric patients have thicker left ventricles?

A

years of work; which also means that ejection fraction lowers (blood leaving the L ventricle)

24
Q

Implications of mitral valve and aortic valve thickening?

A

They may need replacements = operations

25
Q
A