ageing and fragility Flashcards
Describe the stochastic theory of ageing
Random accumulative damage to the body
Describe programmed ageing
Predetermined with changes in gene expression in various stages
What happens to the kidneys as we age
The kidney function reduces as we get older which can be seen by reduced creatinine clearance
What happens to systolic blood pressure as we age
It increases
What happens to diastolic blood pressure as we age
Peaks at 60 and then decreases - important as diastolic blood pressure is what keeps us standing
What happens to cardiac output as we age
Decreases
What happens to vital capacity as we age
decreases
What is frailty
Susceptible state which makes a person more likely to lose function in the face of an environmental challenge
Frailty is dyshomeostasis
What are the frailty syndromes
Falls
Delirium
Immobility
Incontinence
What age is heart failure most common in
85+
