Ageing Flashcards

1
Q

Ageing - Def

A

= the period of the lifespan characterized by a failure to maintain homeostasis under conditions of physiological stress.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Life span at birth for female?

A

79

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Life span at birth for male?

A

74

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Theories of ageing

A
  • Immunologic: diminishing effect of the immune system.
  • Cellular and transcription theory: limited ability to repair cells
  • Atmosphere: effect of UV light + activate the chemicals to cause cellular damage leading to ageing.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Biological & physiological theories of ageing

A
  • Wear & tear theory
  • Autoimmunity theory
  • Free radical theory
  • Programmed (cellular) theory
  • Somatic mutation theory
  • Homeostatic theory
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

! Characteristics of disease in old age

A
  • Rapid worsening and complications are common.
  • Multiple causes: one problem with many causes ➤ treat all the causes.
  • Variable presentation of disease ➤ Common presentations include: incontinence, falls, dementia and confusion ➤ Virtually any disease may present with these.
  • More time is required for recovery ➤ due to impairment in homeostatic mechanism and loss of physiological reserve.
  • Impaired metabolism and excretion of drugs: doses may need lowering to avoid side effects
  • Social factors: are important for quick recovery.
  • Multiple pathology: Ex: senile cataract + arthritis = falls
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Examples of questions to ask in the Hx

A
  • Obtain home details ➤ stairs, access to toilet
  • Medication ➤ What? When?
  • Social input ➤ regular visitors
  • Type of care
  • Speak to others ➤ relatives, neighbours, GP
  • Plan and get involved in a care plan.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Geriatric assessment

A
  • Measurement of the knee height.
  • Nutrition ➤ Body mass index, Height calculation, Weight loss, Oral hygiene & dentition
  • Hydration ➤ Skin tumour, Oedema
  • Pulse ➤ Atrial fibrillation
  • Erect and supine blood pressure. ➤ Postural hypotension
  • Hearing ➤ Wax, Hearing aid
  • Vision ➤ Visual acuity, Glasses, Cataract
  • Cognitive function ➤ Abbreviated mental test
  • Muscles ➤ Wasting, Strength
  • Per rectum ➤ Faecal impaction, Prostate, Size, Consistency, Anal tone
  • Skin ➤ Wounds, Ulcer, Infection, Swelling
  • Joints ➤ Deformity, Pain, Swelling, ROM
  • Gait and balance ➤ Get up and go test
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Abbreviated mental test

A
  • What is the time?
  • What year is it?
  • What is the name of the place …?
  • How old are you?
  • What is your date of birth?
  • Please memorise the following address- 6 Netherhall gardens
  • When did first world war begin?
  • Who is the present monarch?
  • Please count backward from 20 to 1?
  • Can you recognise 2 people?
  • Can you tell me the address I asked you to memorise a few minutes ago?
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

CNS - Changes with ageing & clinical consequences

A

Changes:

  1. Neuronal loss
  2. Cochlear degeneration
  3. Increased lens rigidity
  4. Lens opacification
  5. Anterior horn cell loss
  6. Dorsal column loss
  7. Slowed reaction time

Clinical consequences:

  1. Increased risk of delirium
  2. Presbycusis / loss of high tone hearing
  3. Presbyopia / abnormal near vision
  4. Cataract
  5. Muscle weakness & wasting
  6. Reduced position and vibration sense
  7. Increased postural instability (falls)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Respiratory system - Changes with ageing & clinical consequences

A

Changes:

  1. Reduced lung elasticity and alveolar support
  2. Increased chest wall rigidity
  3. Increased V/Q mismatch
  4. Decline in alveolar surface area (O2)
  5. Reduced cough and ciliary function

Clinical consequences:

  1. Reduced vital capacity and peak expiratory flow
  2. Increased residual volume
  3. Reduced inspiratory reserve volume
  4. Reduced arterial O2 saturation
  5. Increased risk of infection
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

CVS - Changes with ageing & clinical consequences

A

Changes:

  1. Reduced maximum heart rate
  2. Dilation of aorta
  3. Reduced elasticity of conduit / capacitance vessels/aorta
  4. Reduced number of pacing myocytes in sinoatrial node

Consequences:

  1. Reduce exercise tolerance
  2. Widened aortic arch on x-ray
  3. Widened pulse pressure + postural hypotension
  4. Risk of atrial fibrillation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Renal system - Changes with ageing & clinical consequences

A

Changes:

  1. Loss of nephrons
  2. Reduced glomerular filtration rate
  3. Reduced tubular function
Clinical consequences: 
1.	Impaired fluid balance
2.	Risk of dehydration and fluid overload
3.	Impaired drug metabolism and excretion  
Others: 
4.	Bladder capacity reduced
5.	Change in pelvic support
6.	Prostate enlargement 
7.	Urinary incontinence
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Skin - Changes with ageing & clinical consequences

A

Changes:

  1. Thing and sparseness of hair
  2. Hair follicles produce less melanin
  3. Capillary fragility of skin
  4. Atrophy of sweat glands
  5. Decreased response to pain and sensation

Clinical consequences:

  1. Baldness
  2. Greying
  3. Pressure sore
  4. Temperature regulation issues
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

GI system - Changes with ageing & clinical consequences

A

Changes:
1. Reduced motility

Consequences:
1. Constipation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Bones - Changes with ageing & clinical consequences

A

Changes:
1. Reduced bone mineral density

Consequences:
1. Increased risk of osteoporosis

17
Q

Endocrine system - Changes with ageing & clinical consequences

A

Changes:
1. Deterioration in pancreatic B-cell function

Consequences:
1. Increased risk of impaired glucose

18
Q

Clinical concerns in old age - examples of conditions

A
  • Dementia
  • Delirium
  • Incontinence
  • Falls
  • Hypothermia
  • Postural hypotension
  • Stroke
Other less common conditions: 
o	Infection
o	Heart failure
o	Diabetes mellitus
o	Anaemia
o	Hypertension
o	Painful joints
o	Bone diseases
o	Atrial fibrillation 
o	Dizziness & black out
o	Peptic ulceration 
o	Immobility