Age Related Changes

Question 1

CVS

Answer 1

Reduces VO2 max
Autonomic reflex dys
Reduced response to B stimulation
NO change in response to Alpha stimulation
Increased ANP

Question 2

Heart

Answer 2

Decrease in HR, contractility

INCREASE in stroke volume during exercise by increasing end diastolic vol

Question 3

Resp

Answer 3

Chest wall rigidity, reduced muscle strenth

Increased residual vol, reduced VC, reduced func alveolar surface area, increase VQ mismatch

Question 4

Renal

Answer 4

Reduced nephrons
Reduced renal blood flow
Reduced urine cont ability, thirst perception and total body water
More salt sensitive, lower renin levels
Reduced bladder capacity, increased detrusor hyperactivity

Question 5

Heaptic

Answer 5

Reduced blood flow, reduced hepatic mass

No change in LFTs or albumin

Question 6

MSK

Answer 6

Reduces skeletal mass, increased fat

sarcopenia - REVERSAL with weight training!!

Question 7

Hormones

Answer 7

Increased FSH/LH in both sexes
Vaginal changes - reduced lactobacilli secreting peroxide = more UTIs
Higher PTH
TSH can be elevated, accept <10