Affects of Electrolyte Disturbances and Drugs on ECG’s Flashcards

1
Q

What are normal EFC K+ levels

A

3.5-5.3mEq/L (3.5-5.3mmoles/L)

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2
Q

Hyperkalemia levels of K+ and “symptoms”

A

greater than 5.3mEq/L (higher than normal extracellular levels)

  • peaked T waves
  • widening QRS (decrease in conductivity
  • cardiac standstill (arrest)
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3
Q

Hypokalemia levels of K+ and “symptoms”

A

less than 3.5,Eq/L (lower than normal extracellular levels)

  • sluggish repolarization (flat T waves, U waves)
  • bradycardias
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4
Q

Normal Calcium (Ca2+) levels

A

2.2-2.6Eq/L (4.4-5.3mmole/L)

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5
Q

Hypercalcemia levels and “symptoms”

A

greater than 2.6Eq/L

  • Heightened depolarizaton and reploarization
  • spastic contractions (skeletal)
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6
Q

Hypocalcemia

A

lower than 2.2Eq/L

  • increased excitablility
  • Q-T interval gets shorter
  • Tachycardias
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7
Q

do we see hypo/hypercalcemia often

A

no the levels are well regulated by the body

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8
Q

Cardiac Glycosides: example, what do they do

A
  • tend to increase CA+ within the sacroplasmic reticulum
  • increases cadiac contractility (force of contraction)
    can cause conduction blocks – due to decreased excitability and conduction velocity (SA to AV node)
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9
Q

example of a cardiac glycoside drug?

A

ex digitalis, digoxin

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10
Q

what do cardiac glycosides treat

A
  • sometimes used to treat Afib, Aflutte
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11
Q

what do beta Adrenergic Sympathomimetics mimic?

A

sympathetic nervous system

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12
Q

what is a adrenergic sympathomimetic drug treat … what are the side effects

A

ex isoproterenal
slow heart rate (bradycardia) and blocks

side effects = Tachycardias, ventricular arrythmias

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13
Q

Alpha vs beta stimulation

A

??

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14
Q

what is a positive inotrope

A

inotrope is an agent that alters the force or energy of muscular contractions
(increases if positive, decreases if negative)

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15
Q

what is a positive chronotrope

A

Chronotropic drugs may change the heart rate and rhythm by affecting the electrical conduction system of the heart and the nerves that influence it

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16
Q

what is a negative dromotrope

A

A dromotropic agent is one which affects the conduction speed (in fact the magnitude of delay) in the AV node, and subsequently the rate of electrical impulses in the heart.

17
Q

what is a parasympatholytic?

A

Blocks the parasympathetic system by competing with ACH
eg - ATROPINE
- used to treat bradycardia (drug will speed the heart up)

18
Q

what is a Sympatholytic?

A

blocks beta 1 receptors in the heart

  • called beta blockers eg INDEROL
  • used to TREAT tachyarrythmias and hypertension
  • can CAUSE bradycardia, blocks
19
Q

What are Calcium Channel Blockers

A

promote smooth muscle relaxation
eg. Verapamil, Nifedipine
to treat ANGINA PECTORIS and HYPERTENSION
can CAUSE conduction problems (blocks)

20
Q

Antiarrhythmics

A

Quinidine - used to treat atrial arrhythmia’s by suppression of conduction & automaticity
Lidocaine – used for ventricular arrythmias
can cause numerous ECG changes especially if dose to high

** amiodarone is drug of choice now for treating ventricular arythmias like V.fib and V.tach