Affective disorders Flashcards

1
Q

What are mood disorders?

A

Disorders of mental status and function where mood is a core feature
Most common mental disorder
Often associated with anxiety

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2
Q

Are mood disorders always primary problems?

A

No

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3
Q

What is the main classification system we use for mood disorders?

A

ICD-10
International classification of disease
WHO

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4
Q

What are some factors in an affective disorder being classed as abnormal?

A

Persistence of symptoms
Pervasiveness of symptoms
Degree of impairment
Presence of specific symptoms or signs

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5
Q

What are the 3 phases of symptoms of depressive illness?

A

Psychological
Physical
Social

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6
Q

What are some possible changes in thought content in depression?

A
Guilt
Hopelessness
Worthlessness
Any neurotic symptoms like hypochondriasis or obsession
Delusion
Hallucination
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7
Q

How might mood change in depression?

A

Depression
Anxiety
Perplexity
Anhedonia

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8
Q

How might depression affect bodily function?

A
Fatigue
Sleep
Decreased appetite
Libido
Constipation
Pain
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9
Q

How might depression affect psychomotor functioning?

A

Agitation

Retardation

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10
Q

How can depression affect the social sphere?

A
Loss of interests
Loss of confidence
Loss of concentration, registration and memory
Indecisive
Irritability
Apathy
Withdrawal
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11
Q

What is agitation?

A

A state of restless overactivity, aimless or ineffective

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12
Q

What is anhedonia?

A

Loss of ability to derive pleasure from experience

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13
Q

What is apathy?

A

Loss of interest in own surroundings

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14
Q

What is anxiety?

A

An unpleasant emotion in which thoughts of apprehension or fear predominate

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15
Q

Define depression.

A

An unpleasant emotion in which sadness or unhappiness predominates

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16
Q

Define retardation.

A

A slowing of motor responses including speech

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17
Q

What is stupor?

A

A state of extreme retardation in which consciousness is intact
The patient stops moving, speaking, eating and drinking
On recovery can describe clearly events which occurred whilst stuporose

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18
Q

What are some features of somatic syndrome depression?

A
Waking early
Depression worse in morning
Loss of appetite or libido
Objective evidence of psychomotor agitation
or retardation
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19
Q

How is depression classified as mild, moderate or severe?

A

At least 2 of:

  • Abnormally depressed mood for most of day for 2 weeks
  • Loss of interest/pleasure
  • Decreased energy or or increased fatigability

And more from the folowing, to give a total of 4 (mild), 6 (moderate) or 8 (severe)

  • Loss of confidence or self esteem
  • Unreasonable/excessive guilt
  • Recurrent suicidal thought/behaviour
  • Decreased concentration
  • Agitation or retardation
  • Sleep disturbance of any sort
  • Change in appetite
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20
Q

When is the most risk for post-natal depression?

A

30 days following birth

Risk up to 24 months

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21
Q

Is post-natal depression associated with hormone changes?

22
Q

What is the differential diagnosis for depression?

A
Normal reaction to life event
Seasonal Affective Disorder
Dysthymia
Cyclothymia
Bipolar
Stroke, tumour, dementia
Hypothyroidism, Addison’s, Hyperparathyroidism
Infections
23
Q

What are some infections associated with differential diagnosis of depression?

A

Influenza
Infectious mononucleosis
Hepatitis
HIV/AIDS

24
Q

What are some options for antidepressants?

A

SSRIs
TCAs
Monoamine
oxidase inhibitors

25
What are some psychological treatment options for depression?
CBT IPT Individual dynamic psychotherapy Family therapy
26
What are some physical treatments for affective disorders?
ECT Psychosurgery DBS VNS
27
What does SCAN mean?
Schedules for Clinical Assessment in Neuropsychiatry
28
What are some rating scales for depression?
HDRS (Hamilton Depression Rating Scale) BDI-II (Beck Depression Inventory II) HADS (Hospital Anxiety and Depression Scale) PHQ-9 (Patient Health Questionnaire 9)
29
What is mania?
Often associated with grandiose ideas, disinhibition, loss of judgment
30
What does F30.0 mean?
Hypomania | Mild degree of elevation for several days on end
31
What does F30.1 mean?
Mania without psychotic symptoms
32
What does F30.2 mean?
Mania with psychotic symptoms
33
What does F30.8 mean?
Manic episodes, unspecified
34
How might mania present?
``` Elevated mood Increased sociability and sexual energy Decreased need for sleep Irritable Distracted ```
35
What are some psych differential diagnoses with mania?
``` Mixed affective state Schizoaffective disorder Schizophrenia Cyclothymia ADHD Drugs and Alcohol ```
36
What are some medical differential diagnoses with mania?
``` Stroke MS Tumour Epilepsy AIDS Neurosyphilis Cushing's, SLE, hyperthyroidism ```
37
What is a scale used to rate mania?
Young Mania Rating Scale (YMRS)
38
What are some antipsychotics used for mania?
Olanzapine Risperidone Quetiapine
39
What are some mood stabilisers used for mania?
Sodium Valproate Lamotrigene Carbamazepine Lithium
40
Can ECT be used for mania?
Yes
41
What is bipolar affective disorder?
Repeated (2+) episodes of depression AND mania or hypomania
42
What are some risk factors for bipolar disorder?
Industrialised nations Males Mean onset is 21
43
What are some risk factors for depression?
Highest risk for age 18-44, mean onset at 27 Females Adverse life events, especially losses
44
Who is less likely to get MDD?
Employed Financially independent Stable marriage
45
Is lower education attainment associated with MDD?
Yes
46
What proportion of people with major depression die by suicide?
15%
47
What proportion of people with major depression?
80+%
48
What proportion of people with bipolar disorder/mania die by suicide?
10%
49
What proportion of people with bipolar disorder/mania have further episodes?
90%
50
What is the difference between grief and depression?
Grief includes longing/yearning for the loved one Positive emotions can still be experienced Symptoms worst when thinking about the deceased person People often want to be with others whereas people with depression tend to want to be alone
51
What is prolonged grief disorder?
Marked distress and disability caused by the grief reaction | Persistence of this distress and disability more than 6m after a bereavement