Affective Disorders Flashcards
What are mood disorders?
Disorders of mental status and function where altered mood is the core feature
Refers to states of depression and mania
Classifications of mood disorders
ICD - International Classification of Disease
DSM - Diagnostic and Statistical Manual of Mental Disorders
What is depression (symptom)?
Can be an emotion within the range of normal experience
What is depression (syndrome)?
A constellation of symptoms and signs
What is depression (recurrent illness)?
Recurrent depressive disorder
What are the spheres of the symptoms of depressive illness?
Psychological
Physical
Social
What are the psychological symptoms of depressive illness?
Change in mood - depression - anxiety - perplexity - anhedonia Change in thought content - guilt - hopelessness - worthlessness - delusions and hallucinations
What is anhedonia?
Loss of ability to derive pleasure from experience
What are the physical symptoms of depressive illness?
Change in bodily function - energy (fatigue) - sleep - appetite (weight loss) - libido - constipation - pain Change in Psychomotor functioning - agitation - retardation
What are the social symptoms of depressive illness?
Loss of interests
Irritability
Apathy
Withdrawal, loss of confidence, indecisive
Loss of concentration, registration and memory
Depression
Must last for at least two weeks
No hypomanic or manic episodes in lifetime
Not attributable to psychoactive substance use or organic mental disorder
If psychotic symptoms or stupor then severe depression with psychotic symptoms
- Need to exclude other psychotic illnesses first like schizophrenia
General criteria of mild depression
At least two of =>
- Depressed mood that is abnormal for most of the day almost everyday for the past two weeks, largely uninfluenced by circumstances
- Loss of interest or pleasure
- Decreased energy or increased fatigability
Additional to give at least four =>
- Loss of confidence or self esteem
- Unreasonable feelings of guilt or self reproach or excessive guilt
- Recurrent thoughts of death by suicide or any suicidal behaviour
- Decreased concentration
- Agitation or retardation
- Sleep disturbance of any sort
- Change in appetite
General criteria of moderate depression
At least two of =>
- Depressed mood that is abnormal for most of the day almost everyday for the past two weeks, largely uninfluenced by circumstances
- Loss of interest or pleasure
- Decreased energy or increased fatigability
Additional to give at least four =>
- Loss of confidence or self esteem
- Unreasonable feelings of guilt or self reproach or excessive guilt
- Recurrent thoughts of death by suicide or any suicidal behaviour
- Decreased concentration
- Agitation or retardation
- Sleep disturbance of any sort
- Change in appetite
General criteria of severe depression
At least two of =>
- Depressed mood that is abnormal for most of the day almost everyday for the past two weeks, largely uninfluenced by circumstances
- Loss of interest or pleasure
- Decreased energy or increased fatigability
Additional to give at least eight =>
- Loss of confidence or self esteem
- Unreasonable feelings of guilt or self reproach or excessive guilt
- Recurrent thoughts of death by suicide or any suicidal behaviour
- Decreased concentration
- Agitation or retardation
- Sleep disturbance of any sort
- Change in appetite
Differential diagnosis
Normal reaction to life event SAD Dysthymia Cyclothymia Bipolar Stroke, tumour, dementia Hypothyroidism, Addison’s, Hyperparathyroidism Infections – Influenza, infectious mononucleosis, hepatitis, HIV/AIDS Drugs
Treatments of depression
Antidepressants
Psychological treatments
Physical treatments
Types of antidepressant
Selective Serotonin Reuptake Inhibitors (SSRIs)
Tricyclic antidepressants (TCAs)
Monamine Oxidase Inhibitors