Affective Disorders Flashcards

1
Q

What are Mood Disorders?

A
  • Disorders of mental status and function where altered mood is the core feature
  • Referes to States of depression and of elevated mood - Mania
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2
Q

Describe the psychological symptoms of depression?

A
Change in mood
- Depression
- Anxiety
- Perplexity 
- Anhedonia - Dosent take pleasure from activities 
Change in thought content 
- Guilt
- Hopelessness
- Worthlessness
- Neurotic symptomatology, 
- Ideas of reference
- Delusions and hallucinations
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3
Q

Describe the Physical symptoms of depression?

A
Change in physical sphere
- Energy 
- Sleep 
- Apetite 
- Libido
- Constipation
Change in Psychmotor functioning
- Agitation
- Retardation
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4
Q

Describe the social symptoms of depression?

A

The social sphere

  • Loss of interests
  • Irritability
  • Apathy
  • Withdrawal, loss of confidence, indecisive
  • Loss of concentration, Registration & memory
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5
Q

What are the symptoms of depression and how is Depression listed in the ICD-10

A
  • Last for around 2 weeks
  • No hypomaniac or maniac episodes
  • No attributable substance use or organic mental disorder
  • If psychotic symptoms or stupor then severe depression with psychotic symptoms
  • Need to exclude other psychotic illness’s like schizophrenia
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6
Q

Describe somatic syndrome

A
  • Marked loss in interest or pleasure in activities that are normally pleasurable
  • Lack of emotional reactions to events or activities that normally produce an emotional response
  • Waking up 2 hrs before the normal time
  • Depression in the morning
  • Objective evidence of psychomotor agitation or retardation
  • Marked loss of apetite
  • Weight loss (5% of body weight in a month)
  • Marked loss of libido
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7
Q

Describe mild depression

A

Least 2 of:

  • Depressed mood that is abnormal for most of the day almost everyday for the last 2 weeks largely uninfluenced by circumstances
  • Loss of interest or pleasure
  • Decreased energy or increased fatiguability

Addition of any to give 4:

  • Loss of confidence or self-esteem
  • Unreasonable feelings of guilt or self-approach
  • Recurrent thoughts of death by suicide or suicidal behaviour
  • Decreased concentration
  • Agitation or retardation
  • Change in apetite
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8
Q

Describe moderate depression

A

Least 2 of:

  • Depressed mood that is abnormal for most of the day almost everyday for the last 2 weeks largely uninfluenced by circumstances
  • Loss of interest or pleasure
  • Decreased energy or increased fatiguability

Addition of any to give 6:

  • Loss of confidence or self-esteem
  • Unreasonable feelings of guilt or self-approach
  • Recurrent thoughts of death by suicide or suicidal behaviour
  • Decreased concentration
  • Agitation or retardation
  • Change in apetite
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9
Q

Describe severe depression

A

Least 2 of:

  • Depressed mood that is abnormal for most of the day almost everyday for the last 2 weeks largely uninfluenced by circumstances
  • Loss of interest or pleasure
  • Decreased energy or increased fatiguability

Addition of any to give 6:

  • Loss of confidence or self-esteem
  • Unreasonable feelings of guilt or self-approach
  • Recurrent thoughts of death by suicide or suicidal behaviour
  • Decreased concentration
  • Agitation or retardation
  • Change in apetite
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10
Q

Describe Post-Natal depression

A

Increased risk of psychiatric admission in the 30 days following childbirth

  • 75% of women experience blues
  • 15% of women develop Major depressive disorder within 3-6 months

Note: Apparently no association with hormonal changes

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11
Q

What are the range of anti-depressants available for

A
  • Selective Seretonin Reuptake inhibitors
  • Tricyclic Anti-Depressants
  • Monamine Oxidase inhibitors
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12
Q

What are the psychological treatments available

A
  • Cognitive Based Therapy
  • Individual dynamic psychotherapy
  • Family therapy
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13
Q

What are the physical treatments

A
  • ECT
  • Psychosurgery
  • DBS
  • VNS
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14
Q

What are the measurement tools available for

A
  • Structured Clinical interview for DSM
  • SCAN (Schedules for Clinical Assessment in Neurophysciatary)
  • Hamilton Depression Rating Scale
  • Beck Depression Inventory II
  • Hospital Anxiety and Depression Scale
  • Patient Health Questionnaire
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15
Q

What is Mania?

A
  • A term to describe a state of feeling, mood, that can range from near normal experience to severe, threatening illness
  • Rarely a symptom, more associated with grandiose ideas, disinhibition, loss of judgment
  • Typically considered as a form of pathological inappropriate elevated mood
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16
Q

What is the ICD-10 classification of hypomania

A
  • Lesser degree of mania, no psychosis
  • Mild elevation of mood for several days on end
  • Increased energy and activity, marked feeling of wellbeing
  • Increased sociability, talkativeness, overfamiliarity, increased sexual energy, decreased need for sleep
  • May be irritable
  • Concentration reduced, new interests, mild overspending
  • Not to the extent of severe disruption of work or social rejection
17
Q

What is the ICD-10 classification of mania

A
  • 1 Week, severe enough to disrupt ordinary work and social activities more or less completely
  • Elevated mood, increased energy, overactivity, pressure of speech, decreased need for sleep
  • Disinhibition
  • Grandiosity
  • Alteration of senses
  • Extravagant spending
    Can be irritable rather than elated.
18
Q

What are the tools to measure symptoms?

A
  • SCID
  • SCAN
  • Young mania rating scale
19
Q

What are the treatments?

A

Antipsychotics

  • Olanzapine
  • Risperidone
  • Quetiapine

Mood Stabilisers

  • Sodium Valproate
  • Lamotrigine
  • Carbamazepine

Lithium
ECT

20
Q

What is bipolar effective disorder and how is it classed ?

A
  • Bipolar Affective Disorder consists of repeated (2+) episodes of depression and mania or hypomania
  • If no mania or hypomania then diagnosis is recurrent depression.
  • If no depression the diagnosis is hypomania or bipolar disorder
    (In DSM-5 a single episode of mania is sufficient to diagnose bipolar disorder.)
21
Q

What is the epidemology?

A
  • Lifetime prevalence rate: 0.7-1.6

- Point prevelance rate of mania: