Aerie

Question 1

The first FDA-approved medication in its class to lower elevated eye pressure in patients with open-angle glaucoma and ocular hypertension

Answer 1

Rhopressa

Question 2

Rhopressa Active Ingredient

Answer 2

Netarsudil

Question 3

Rhopressa provides consistent eye pressure reduction by supressing the _____ _______.

Answer 3

ROCK enzymes

Question 4

MOST Study

Answer 4

Rhopressa provided consistent, additional IOP reduction regardless of the patient’s current regimen by providing patients with an additional 4mmHG in IOP reduction whether added to monotherapy or combination therapy.

Question 5

MOA of ROCK Inhibitors

Answer 5

Work to relax the Trabecular Meshwork to improve aqueous humor outflow, which reduces pressure and also decreases EVP

Question 6

The number 1 side effect for Rhopressa is ________, which effects roughly ___% of patients

Answer 6

Hyperemia; 53%

Question 7

In __ / 10 Rhopressa patients overall, hyperemia was either not reported or graded as mild

Answer 7

9/10

Question 8

Discontinuation rate for Rhopressa due to Hyperemia

Answer 8

6%

Question 9

T/F There are no labeled contraindications for Rhopressa

Answer 9

True

Question 10

Dosing regimen for Rhopressa / Rocklatan

Answer 10

Patients will administer one drop in the affected eye every evening

Question 11

“One Drop Addition”

Answer 11

Rhopressa

Question 12

Rhopressa Simple Call to Action

Answer 12

Make Rhopressa your 1st add to a PGA and gen an additional >4 mmHg IOP reduction

Question 13

A unique, once-daily eye drop that helps reduce eye pressure through two different pathways.

Answer 13

Rocklatan

Question 14

First and only fixed-dose combination in the US that combines 2 compounds with true 24-hour dosing within the simplicity of a single bottle

Answer 14

Rocklatan

Question 15

The ____ and _____ inhibitors of Rocklatan provide patients with superior efficacy vs its individual components at all time points in Phase 3 clinical trials

Answer 15

PGA and ROCK

Question 16

Rocklatan Active Ingredients

Answer 16

Netarsudil

Latanaprost

Question 17

Rocklatan vs Latanoprost Clinical Trials

Answer 17

Nearly twice as many Rocklatan patients achieved a 30% IOP reduction
3x as many Rocklatan patients achieved an IOP reduction of 40% or more vs latanoprost
Nearly 60% of Rocklatan patients achieved an IOP reduction of roughly 16mmHg (compared to only 37% of latanoprost patients)

Question 18

Rocklatan maintained ________ over its individual components in the 12-month study

Answer 18

Superiority

Question 19

Most common side effect for Rocklatan is _______ and affects about __% of patients

Answer 19

Hyperemia; 59%

Question 20

For __% of those Rocklatan patients who experienced hyperemia, it was mild and the severity did not increase over time

Answer 20

90%

Question 21

Only __% of Rocklatan patients discontinued treatment due to hyperemia

Answer 21

5%

Question 22

Rocklatan Simple Call to Action

Answer 22

Replace latanoprost with Rocklatan for proven superiority and achieve target IOP with simplified dosing

Question 23

Rhopressa is for patients who: (3)

Answer 23

Need 4 mmHg of IOP reduction regardless of baseline
Need consistent IOP reduction when adding a medication
Can’t take a beta blocker or alpha agonist due to contraindications

Question 24

Rocklatan for patients who: (4)

Answer 24

Need lower IOP when a PGA isn’t enough
Achieving target IOP in a single bottle is important
Want to minimize the number of drops and bottles for simplicity
Want to reduce their number of copays

Question 25

“The One Drop Difference”

Answer 25

Rocklatan

Question 26

Rhopressa and Rocklatan Copay offer

Answer 26

Most of those commercially insured and covered patients will pay as little as $25