AEDs and Side Effects Flashcards
Mnemonic to remember first and second line AEDs for generalised seizures?
female orgasms are general, so “Vaginas Like Cocks” = Valproate, Lamotrigine, Carbamazepine for general
But don’t give Vagina to Vaginas if they are child bearing age!
Mnemonic to remember first and second line AEDs for focal seizures?
male orgasms are focal, so “Cocks Like Vaginas” = Carbamazepine, Lamotrigine, Valproate for focal
What is first line for absence seizures?
Ethosuximide and sodium valproate
sux to have absence seizures
Which AED blocks voltage-gated T-type Ca2+ channels?
Ethosuximide
Which AED can cause weight loss?
Topiramate
can be licensed for weight loss in some places
Mnemonic to remember which AEDs cause SJS?
Ethan, Carl and Larry are friends with Steven and Johnson
Ethosuximide
Carbamazepine
Lamotrigine
Which AED retains fat / causes weight gain?
“Valproate increases Veight”
or
“Walproate increases Weight”
Which AED interferes with folate?
“Phenytoin affects Pholate /Folate”
megaloblastic anaemia and peripheral neuropathy
Which AED causes osteomalacia?
“Phenytoin brings my toe in”
and there are bones in your toe
Which AED causes SIADH?
Carbamazepine
Which AED is used for trigeminal neuralgia?
Carbamazepine
“chew CARBs with cheek = trigeminal neuralgia”
Which AED has an unknown mechanism?
Levetiracetam
“how to you levitate? I don’t know how says levitating magician”
Important side effect of lamotrigine?
“Lamotrigine has Life threatening rash”
aka Larry in Ethan, Carl and Larry
What are the PHENYTOIN side effects? (acronym)
P P450 inducer Principally H Hirsuitism E Enlarged gums NY NYstagmus T Teratogen O Osteomalacia I Interferes with folate N Neuropathy
What are the VALPROATE side effects? (acronym)
V Vomiting A Alopecia L Liver toxicity P Pancreatitis R Retained fat O Oedema A Appetite increase T Tremor E Enzyme inhibitor P450 at End
