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Psych Drug Names > AEDs > Flashcards

AEDs Flashcards

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1
Q

Levetiracetam brand name?

A

keppra generic name?

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2
Q

tiagabine brand name?

A

gabitril generic name?

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3
Q

topiramate brand name?

A

topamax generic name?

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4
Q

vigabatrin brand name?

A

sabril generic name?

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5
Q

Benzodiazepine indications?

A

First line for generalized seizures. Anesthesia induction. Anxiety. Eclampsia. Alcohol withdrawal/detox.

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6
Q

MoA benzodiazepines?

A

increase frequency of Cl- channel opening: which is a GABA inhibitory channel

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7
Q

Side Effects of benzos?

A

Dependence, CNS/respiratory depression, reduced REM sleep

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8
Q

What is the antidote for benzo overdose?

A

flumazenil

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9
Q

MoA barbituates?

A

increases duration of Cl- channel opening; Cl- influx inhibits excitatory neuron firing and increases inhibitory GABA influence

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10
Q

Side Effects of barbituates?

A

CNS, Respiratory depression, dependence, P450 inducer

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11
Q

Indication for phenobarbital?

A

AED

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12
Q

Two things to consider when using phenobarbital?

A
  1. have to monitor plasma levels 2. addiction potential
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13
Q

SE of phenobarbital specifically?

A
  1. ataxia 2. fatigue/somnolence 3. paradoxical excitement
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14
Q

Phenytoin brand name?

A

dilantin generic name?

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15
Q

MoA for phenytoin:

A
  1. Blocks activation of Na+ channels which inhibits glutamate release
  2. Also Class IIB antiarrhythmic
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16
Q

Indications for phenytoin?

A
  1. status epilepticus 2. tonic-clonic/generalized seizures1
17
Q

Side Effects of phenytoin?

A
  1. hirsuitism 2. gingival hyperplasia 3. neuropathy 4. megaloblastic anemia 5. teratogenic 6. drug induced SLE 7. induce cytochrome p450 8. teratogenic
18
Q

what drug is first line for tonic-clonic seizures?

A

valproic acid

19
Q

valproic acid brand name?

A

depakote generic name?

20
Q

valpoic acid MoA?

A

Increases concentration of GABA by inhibiting activation of voltage gated Na+ channels

21
Q

3 indications for valproic acid?

A
  1. first line for tonic clonic seizures 2. bipolar disorder 3. migraine ppx
22
Q

MC side effect of valproic acid?

A

GI upset

23
Q

In what condition is valproic acid CI in?

A

Pregnancy

24
Q

Mneumonic for side effects of valproic acid?

A

V-A-L-P-R-O-A-T-E V - vomiting A - alopecia L - liver toxicity P - Pancreatitis and Pancytopenia R - retaining (Weight gain) O - Oedema A - appetite increase T - tremor E - enzyme inhibitor P450

25
Q

Use and MoA for tiagabine/gabitril?

A

AED adjunct / decreases presynaptic uptake of GABA increasing GABA concentration in the synapse

26
Q

Use of vigabatrine/sabril?

A

Infantile spasms

Psych Drug Names (1 decks)

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