AE effects - Cholinergic Flashcards

1
Q

Botulinum toxin

A

Injection site rxn

Weakness of injected muscles + adjacent

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2
Q

D-tubocurarine

A

Nn (ganglionic blockade)
Releases histamine from mast cells –. allergic rxn
SKM paralysis

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3
Q

Succinylcholine

A

HypER-K (if taking digoxin or K sparing, or tissue injuries/burns)
Malignant hyperthermia

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4
Q

Bethanechol & Pilocarpine

A

mAChR agonist AE:

GI:
Cramps
NVD

diaphoresis/hyerhidrosis
hypersalivation
lacrimation
urinary urgency
visual distrubances
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5
Q
Atropine
Scopolamine
Oxybutynin
Tolterodine
Ipratropium
A

mAChR antag AE (antichol AE)

Xerostomia
Urinary retention
constipation
confusion
drowsines
angle-closure glaucoma attacks
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6
Q
Donepezil
Physostigmine
Pyridostigmine
Echothiophate
Malathion
A

mAChR agonist AE:

GI:
Cramps
NVD

diaphoresis/hyerhidrosis
hypersalivation
lacrimation
urinary urgency
visual distrubances

SKM AE via depolarization blockade:
muscle cramps
fasciculations
weakness

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