Adverse reactions to drugs and, drugs and driving Flashcards
1
Q
Drugs that cause hyperkalemia
A
- ACi/ARB
- Potassium sparing diuretic
2
Q
Drugs that cause hypokalaemia
A
- Beta2 agonist
- Corticosteroid
- Loop + thiazide
- Theophylline
3
Q
Drugs that cause hyponatraemia
A
- Antidepressant
- Loop + thiazide
4
Q
Drugs that cause thromboembolism
A
- Oestrogen: combined contraceptive, HRT
- Cytotoxic drugs: belomycin, tamoxifen, vinca alkaloid, thalidomide
5
Q
Drugs that cause bone marrow suppression
A
- Amino salicylate
- Anti-epileptics: carbamazepine, phenytoin, valproate
- Carbimazole
- Clozapine
- Methotrexate
6
Q
Drugs that cause QT prolongation
A
Antipsychotics (pimozide + haloperidol)
Domperidone
Erythromycin + clarithromycin
Quinolone
SSRI (citalopram + escitalopram)
TCA (clomipramine)
7
Q
Drugs that cause bradycardia
A
- Amiodarone
- Beta blocker
- Digoxin
- Rate limiting CCB (diltiazem + verapamil)
8
Q
Drugs that cause serotonin syndrome
A
- Antidepressants
- 5-HT1 agonist (triptans)
- 5-HT3 antagonist (ondansetron)
9
Q
Drugs that lower seizure threshold
A
- Antipsychotic
- Quinolone
- SSRI
- Tramadol
10
Q
Drugs that cause peripheral neuropathy
A
- Amiodarone
- Isoniazid
- Metronidazole
11
Q
Oral side effects
A
- Oral candidiasis: ICS, abx
- Osteonecrosis of jaw: bisphosphonates
- Gingival hypertrophy: phenytoin
12
Q
Drugs that cause ototoxicity
A
- Aminoglycoside
- Loop diuretic
13
Q
Drugs that cause phototsensitivity
A
counselling: avoid sun exposure or sunbeds, use high SPF sunscreen
- Amiodarone
- Isotretinoin
- Phenothiazine antipsychotic
- Quinolone
- Tetracycline (doxycycline + demeclocycline)
14
Q
Drugs that cause contact sensitisation
A
- Chlorpromazine
- Cytotoxic drug
- Methotrexate
