Adverse Reactions

Question 1

Serotonin syndrome

Answer 1

Antidepressants
Triptans
St John’s Wart
Second generation antipsychotics
MAO inhibitors
Tramadol
Dextromethorphan (cough syrup)

Question 2

Hyperprolactinemia

Answer 2

Antipsychotics

Question 3

Extrapyramidal side effects
- Twitch
- Akathesia
- Parkinsonism
- Rabbit syndrome

Answer 3

Antipsychotics

Question 4

Tardive Dykinesia

Answer 4

Antipsychotics

Question 5

Neuroleptic malignant syndrome

Answer 5

Antipsychotics

Question 6

Leukopenia

Answer 6

Clozapine

Question 7

Arrhythmia, hand tremors, hypo/hyperthyroidism, weight gain, tremors, metallic taste, dry mouth, polyuria

Answer 7

Lithium

Question 8

Anterograde amnesia

Answer 8

Benzodiazepines

Question 9

Daytime drowsiness and dizziness
Increased risk of falls
Nightmares
Tolerance
Dependence

Answer 9

Benzodiazepines
Z-sedatives (lesser)
Lemborexant (+ worsens depression)

Question 10

Sleepwalking, amnesia, bitter metallic taste, behavioural effects (nightmares, anger)

Answer 10

Z-sedatives

Question 11

Drowsiness, headache, dizziness, nausea, vivid dreams

Answer 11

Melatonin

Question 12

Drowsiness, dizziness, headache, upset stomach

Answer 12

Valerian

Question 13

Nausea & vomiting, diarrhea, bradycardia, muscle cramps, vertigo, insomnia, incontinence, increased gastric acid

Answer 13

Cholinesterase inhibitors

Question 14

Bleeding, seizures, nausea, vomiting, diarrhea

Answer 14

Ginkgo biloba

Question 15

Nausea, vomiting, stomach pain, stomach ulcers, acute renal failure, bleeding, worsening blood pressure & heart failure, bronchoconstriction, delay labor

Answer 15

NSAIDs

Question 16

Constipation, nausea, sedation, respiratory depression, dry mouth, pseudoallergy, addiction

Answer 16

Opioids

Question 17

Chest discomfort

Answer 17

Triptans

Question 18

Nausea, vomiting, burping, liver toxicity

Answer 18

Butterbur

Question 19

Growth suppression, rebound hyperactivity, suicidal ideation, tics

Serious: cardiac death, priapism

Answer 19

CNS stimulants
Atomoxetine

Question 20

Reduce blood pressure & heart rate, sedation, dizziness, dry mouth, headache

Answer 20

Clonidine
Guanfacine

Question 21

Nystagmus, ataxia, slurred speech, impaired coordination, cognitive impairment, sedation

Answer 21

Phenytoin

Question 22

Steven Johnson syndrome

Answer 22

Phenytoin

Question 23

Toxic epidermal necrolysis

Answer 23

Phenytoin

Question 24

Osteomalacia

Answer 24

Phenytoin

Question 25

Gingival hyperplasia

Answer 25

Phenytoin

Question 26

Sudden sleep attacks

Answer 26

Levodopa Pramipexole Ropinirole Rotigotine

Question 27

Impulsive behaviours

Answer 27

Levodopa Pramipexole Ropinirole Rotigotine

Question 28

Nausea, vomiting, taste alteration, dark urine, orthostatic hypotension, psychosis, depression, sleep behaviour disorder, motor complications

Answer 28

Levodopa Pramipexole Ropinirole Rotigotine

Question 29

Acting out dreams

Answer 29

Levodopa

Question 30

Abrupt withdrawal results in Parkinsonism-Hyperpyrexia Syndrome

Answer 30

Levodopa

Question 31

Constipation, dry mouth, blurry vision; urine retention, tachycardia

Answer 31

Anticholinergic drugs: - Benztropine - Tranylcypromine