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Drugs & Disease Module 3 CNS > Adverse Reactions > Flashcards

Adverse Reactions Flashcards

1
Q

Serotonin syndrome

A

Antidepressants
Triptans
St John’s Wart
Second generation antipsychotics
MAO inhibitors
Tramadol
Dextromethorphan (cough syrup)

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2
Q

Hyperprolactinemia

A

Antipsychotics

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3
Q

Extrapyramidal side effects
- Twitch
- Akathesia
- Parkinsonism
- Rabbit syndrome

A

Antipsychotics

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4
Q

Tardive Dykinesia

A

Antipsychotics

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5
Q

Neuroleptic malignant syndrome

A

Antipsychotics

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6
Q

Leukopenia

A

Clozapine

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7
Q

Arrhythmia, hand tremors, hypo/hyperthyroidism, weight gain, tremors, metallic taste, dry mouth, polyuria

A

Lithium

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8
Q

Anterograde amnesia

A

Benzodiazepines

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9
Q

Daytime drowsiness and dizziness
Increased risk of falls
Nightmares
Tolerance
Dependence

A

Benzodiazepines
Z-sedatives (lesser)
Lemborexant (+ worsens depression)

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10
Q

Sleepwalking, amnesia, bitter metallic taste, behavioural effects (nightmares, anger)

A

Z-sedatives

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11
Q

Drowsiness, headache, dizziness, nausea, vivid dreams

A

Melatonin

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12
Q

Drowsiness, dizziness, headache, upset stomach

A

Valerian

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13
Q

Nausea & vomiting, diarrhea, bradycardia, muscle cramps, vertigo, insomnia, incontinence, increased gastric acid

A

Cholinesterase inhibitors

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14
Q

Bleeding, seizures, nausea, vomiting, diarrhea

A

Ginkgo biloba

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15
Q

Nausea, vomiting, stomach pain, stomach ulcers, acute renal failure, bleeding, worsening blood pressure & heart failure, bronchoconstriction, delay labor

A

NSAIDs

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16
Q

Constipation, nausea, sedation, respiratory depression, dry mouth, pseudoallergy, addiction

A

Opioids

17
Q

Chest discomfort

A

Triptans

18
Q

Nausea, vomiting, burping, liver toxicity

A

Butterbur

19
Q

Growth suppression, rebound hyperactivity, suicidal ideation, tics

Serious: cardiac death, priapism

A

CNS stimulants
Atomoxetine

20
Q

Reduce blood pressure & heart rate, sedation, dizziness, dry mouth, headache

A

Clonidine
Guanfacine

21
Q

Nystagmus, ataxia, slurred speech, impaired coordination, cognitive impairment, sedation

A

Phenytoin

22
Q

Steven Johnson syndrome

A

Phenytoin

23
Q

Toxic epidermal necrolysis

A

Phenytoin

24
Q

Osteomalacia

A

Phenytoin

25
Q

Gingival hyperplasia

A

Phenytoin

26
Q

Sudden sleep attacks

A

Levodopa
Pramipexole
Ropinirole
Rotigotine

27
Q

Impulsive behaviours

A

Levodopa
Pramipexole
Ropinirole
Rotigotine

28
Q

Nausea, vomiting, taste alteration, dark urine, orthostatic hypotension, psychosis, depression, sleep behaviour disorder, motor complications

A

Levodopa
Pramipexole
Ropinirole
Rotigotine

29
Q

Acting out dreams

A

Levodopa

30
Q

Abrupt withdrawal results in Parkinsonism-Hyperpyrexia Syndrome

A

Levodopa

31
Q

Constipation, dry mouth, blurry vision; urine retention, tachycardia

A

Anticholinergic drugs:
- Benztropine
- Tranylcypromine

Drugs & Disease Module 3 CNS (1 decks)

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