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Psychopharm > Adverse Effects, Special Considerations > Flashcards

Adverse Effects, Special Considerations Flashcards

1
Q

Short Half-Life

A

Zoloft

Paxil

Effexor

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2
Q

Intermediate Half-Life

A

Celexa

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3
Q

Potential to cause GI Issues

A

Zoloft

Celexa

Effexor

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4
Q

Elderly population MDD

A

Effexor (watch out for hypertension)

Cymbalta (watch out for liver damage)

Remeron

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5
Q

Increased risk of seizure

A

Wellbutrin
*rule out TBI, bulimia, anorexia

Clozapine–especially combined with LIthium

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6
Q

Increased risk of mania

A

Effexor

Prozac

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7
Q

Significant weight gain

A

Remeron, Paxil

Most AP’s, but Clozapine and Zyprexa the most

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8
Q

Also treat neuropathic pain

A

TCA’s

SNRI–effexor, cymbalta

MAOI’s

Lamictal, Depakote

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9
Q

Lethal in overdose

A

TCA’s

Lithium

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10
Q

Few drug-drug interactions

A

Celexa–fewest of all SSRI’s

Zoloft

Effexor

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11
Q

Significant drug-drug interactions

A

Paxil

Prozac

Abilify

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12
Q

Risk of Agranulocytosis

A

Clozapine

Remeron

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13
Q

Possible liver damage (transaminitis)

A

Cymbalta

Atypicals: Clozapine Seroquel, Zyprexa

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14
Q

Increased risk of hypertension

A

Effexor

MAOI’s + Tyramine rich foods

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15
Q

Good GI absorption

A

Prozac

Paxil

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16
Q

Choices for treatment-resistant depression

A

MAOI’S

Effexor

17
Q

Long half-life

A

Prozac–decreased risk of overdose and withdrawal

18
Q

Reduce painful physical symptoms of depression

A

Cymbalta

19
Q

Low risk of weight gain

A

Cymbalta

Geodon

Abilify

Wellbutrin

20
Q

Q-T prolongation

A

Atypical AP: Sertindole–biggest effect; also Geodon

TCA’s

Wellbutrin

21
Q

Overly sedating

A

Celexa

Cymbalta

Clozapine

Remeron

22
Q

Low risk of inducing mania

A

Wellbutrin

23
Q

Abuse potential, psychosis in large doses

A

Wellbutrin

24
Q

May increase anxiety

A

Celexa

Prozac

Wellbutrin

25
Q

May cause insomnia

A

Cymbalta

Prozac

Wellbutrin

26
Q

Pregnancy Contraindications

A

SSRI: Paxil

BP: Lithium, most Anticonvulsants

27
Q

Risk of Stevens-Johnson Syndrome

A

Lamictal

28
Q

Preganancy, general consideration

A

Highest risk = teratogenesis
*malformation of fetus or fetal organs

*1st trimester poses greatest risk to developing organs

Most drugs cross the placenta, so fetal exposure will continue during pregnancy

29
Q

Good choice for: Depressed elderly, failure to thrive, marked weight loss

A

Remeron

30
Q

GI irritation upon starting Lithium

A

Leave at current dose

Encourage fluid intake

See if side effects improve

31
Q

SSRI’s that have sig. drug interactions with Abilify

A

Prozac

Paxil

32
Q

EPS

A

First generation Typicals, especially high potency: Haldol, Prolixin

33
Q

Akathisia

A

Abilify

34
Q

Orthostatic Hypotension

A

Seroquel

MAOI’s

TCA’s

Psychopharm (13 decks)

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