Adverse Effects of GI Meds

Question 1

constipation, diarrhea, acid base disturbancess, changes in mineral metabolism, absorption

Answer 1

AEs of Antacids

Question 2

HA, fatigue, dizziness, constipation, diarrhea, confusion, altered mentation (particularly in elderly with IV)

Answer 2

AEs of H2 Blockers

Question 3

HA, diarrhea, constipation, abdominal pain

Answer 3

AEs of PPIs

Question 4

Abdominal pain, flatulence, diarrhea, nausea

Answer 4

AEs of Misoprostol

Question 5

constipation, nausea, metallic taste, aluminum toxicity

Answer 5

AEs of Sucralfate

Question 6

black tongue, black stools, salicylism

Answer 6

AEs of Bismuth Subsalicylate

Question 7

headache, dyspepsia, nausea, vomiting, fatigue, bone marrow suppression, reduction in sperm counts, hepatitis, pulmonitis

Answer 7

AEs of Aminosalicylates

Question 8

hypersensitivity causing pancreatitis, fever, rash, hepatitis, leukopenia

Answer 8

AEs of Azathioprine & 6-MP

Question 9

hepatotoxicity, pulmonary fibrosis, and bone marrow suppression

Answer 9

AEs of Methotrexate

Question 10

toxicity equating nephrotoxicity, risk of infection, seizures, HTN, LFT abnormalities

Answer 10

AEs of Cyclosporine

Question 11

reactivation of serious infections (TB, hep B), exacerbation of heart failure, & lymphoma

Answer 11

AEs of Anti-TNF-Alpha Biologics

Question 12

reaction causing fever, chest pain, hypotension, & dyspnea

Answer 12

AEs of Infliximab IV administration

Question 13

progressive multifocal leukoencephalophathy

Answer 13

AEs of Biologics– Natalizumab & Vedolizumab