Adverse Effects

Question 1

Drugs to Avoid in Pregnancy

Answer 1

Certain antibiotics: tetracyclines, aminoglycosides, sulphonamides and
trimethoprim, quinolones
-
- ACEi/ARBs
- Statins
- Warfarin
- Sulfonylureas
- Retinoids (including topical)
- Cytotoxic agents
AEDs (consider epilepsy risk plus risk to baby): valproate, carbamazepine and
phenytoin are known to be harmful
-
- Use carbimazole only at low dose in pregnancy or propylthiouracil

Question 2

Drugs to Avoid in Breastfeeding

Answer 2

Medications to avoid in breastfeeding (LAMBAST Cs):
○ Lithium
○ Amiodarone
○ MTX
○ BZDs
○ Aspirin
○ Sulphonamides
○ Tetracyclines
○ Cipro, carbimazole, chloramphenicol, cytotoxics