ADVATE Flashcards
What is ADVATE?
Recombinant antihemophilic factor VIII
How does Advate work?
Advate works by temporarily raising levels of factor VIII in the blood to aid in clotting.
Dosing for Control and Prevention of Bleeding Episodes - Minor
10-20 IU
Dosing for Control and Prevention of Bleeding Episodes - Moderate
15-30 IU
Dosing for Control and Prevention of Bleeding Episodes - Major
30-50 IU
ADVATE is used to _____ and _____ bleeding in adults and children (0-16 years) with hemophilia A
Prevent and control
Your body may form inhibitors to factor VIII. An inhibitor is part of the body’s normal defense system. If you form inhibitors, it may stop ADVATE from _____.
working properly
What is MyPKFit?
Mobile App that tracks infusions and bleeding episodes
The myPKFiT Mobile App is designed to make it convenient for you to record your infusion and bleed events, track your estimated ______ levels following a prophylactic infusion, and export the data for review by your healthcare provider (“HCP”).
Factor VIII
The myPKFiT for Patients Mobile Application (“myPKFiT Mobile App”) is intended for use by patients with hemophilia A being treated with ADVATE [Antihemophilic Factor (Recombinant)] who are ___ years of age or older with a body weight of __ kg or higher, and their caregivers.
16 and 45kg
FREEDOM OF CHOICE™ ______
You may be eligible for _____ trial doses of ADVATE.
Free-Trial Program and 6 Free
Most widely used*
More than ___ billion International Units (IUs) distributed worldwide
33
Extensively studied
Evidence spanning over __ years from ___ prospective studies
Over 15 and from 15
Established formulation
____ _____ full-length molecule, similar to the factor VIII that occurs naturally in the body.
Third generation
___ bleeds experienced by __ of patients during 1 year of prophylaxis (n=22 in the per-protocol group of 53)
0 bleeds, by 42%
