Adv Tech and Imaging 7 - Other Advanced Technologies Flashcards
1
Q
What are the advantages of using PET-MR in pre-treatment?
A
- combines functional information with good tissue definition
- Better diagnostics
- More accurate definition, reducing margins, less dose to healthy tissues
2
Q
What are the disadvantages of using PET-MR in pre-treatment?
A
- Poor definition at edges due to distortion
- Image fusion difficult due to distortion at edges
- Whole body scanner is very recent, not readily available technology
3
Q
What are the pros of using PET-MR (for pretreat)?
A
- Functional information that is not possible with CT can be obtained
- Better tissue delineation
- Registration in herent in deditcated PET-MR scanners
- Pre and post treatment assessment
- Potential for dose mpodification, e.g escalation or spatial
4
Q
What are the cons of using PET-MR (for pretreat)?
A
- very costly
- networking and image handling
- spatial resolution, without dedicated PET-MR scanner
- radionucleide production
- MR distortion correction
- further fusion may be needed with CT scans for dose computation
5
Q
MR Simulation, what are the difficulties?
A
- Lack of electron density (correction techniques are available)
- Distortion (correction techniques are available)
- Reference data for linac based on-treatment verification (X-ray based)
6
Q
What is FLASH-RT?
A
- very high doserate
- currently very experimental
- 40Gy/sec
7
Q
What are the challenges of using FLASH?
A
- greater therapeutic index, fewer normal tissue effects compared with conventional doserates and fractionation
- FLASH may cause rapid consumption of oxygen, producing radiation induced hypoxia in normal tissues
- more work needed to understand mechanism
- Accelerators are required to reach such high doserates
- Find ways to reach deeper lesions and cover larger fields
8
Q
What is Immuno-RT?
A
- promotes immune response elsewhere in the body to help body to fight cancer
