Adult Psychopathology Flashcards
(29 cards)
Monozygotic concordance of SCZ?
50%
Post-partum associated with
BAD
First degree relatives of patients with BAD have what risk of any mood disorder?
25%
Porphyria psych symptoms
Commonly manifested by psychiatric symptoms (manic or psychotic appearing)
Commonly as abdominal pain
Mobius Syndrome
Congenital absence of the facial nerves and nuclei with resulting bilateral facial paralysis
Severe anorexia and BUN
Increases BUN from the catabolism
Anorexia: TSH/TRH response, blood, GH
TSh responsiveness to TRH is normal, tend to be anemic, serum GH is elevated in anorexia
Depression and TSh
30% of all patients with major depression do not show an increase in TSH when given TRH
Methadone have really bad side effects?
Nope. No bone decay, loss of libido, or cushing syndrome.
Lithium common s/e
Polyuria, polydipsia, tremor, mental confusion at higher doses
Depakote s/e
GI upset, sedation, tremor at high doses
Risk of MDD suicide
10-15%
MAOI side effects
hypotension but fewer anticholinergic effects
Lacunar strokes on CT/MRI
Hypointensities in subcortical areas
Carbohydrate deficient Transferrin
In alcoholics, transferrin has fewer mono-saccharides attached so an increased ratio of 0,1,2 chain sugars to longer chain sugars is a test for high ethanol intake
SCZ and suicide
30% attempt, 10% complete
MDD and suicide
10-15%
Infarcts and the brain
● Infarcts of the left frontal hemispheres (part of left middle cerebral artery distribution) present with depression whereas on the right frontal hemisphere present with euphoia, inappropriate indifference, or mania.
OCD and brain activity
Increased activity in caudate nucleus, cingulum, and frontal lobes
SCZ and brain
Smaller hippocampus, parahippocampal gyrus, and amygdala
Verbigeration
Repetitive and Meaningless Talk
Dysarthria
Difficulty in articulation
Glosolalia
ability to speak a new language suddenly
Don’t use MAOIs and TCAs in these conditions
○ Don’t use in cardiac conduction disease, constipation, glaucoma, or prostatic hypertrophy
