Adult Psychopathology

Question 1

Monozygotic concordance of SCZ?

Answer 1

50%

Question 2

Post-partum associated with

Answer 2

BAD

Question 3

First degree relatives of patients with BAD have what risk of any mood disorder?

Answer 3

25%

Question 4

Porphyria psych symptoms

Answer 4

Commonly manifested by psychiatric symptoms (manic or psychotic appearing)

Commonly as abdominal pain

Question 5

Mobius Syndrome

Answer 5

Congenital absence of the facial nerves and nuclei with resulting bilateral facial paralysis

Question 6

Severe anorexia and BUN

Answer 6

Increases BUN from the catabolism

Question 7

Anorexia: TSH/TRH response, blood, GH

Answer 7

TSh responsiveness to TRH is normal, tend to be anemic, serum GH is elevated in anorexia

Question 8

Depression and TSh

Answer 8

30% of all patients with major depression do not show an increase in TSH when given TRH

Question 9

Methadone have really bad side effects?

Answer 9

Nope. No bone decay, loss of libido, or cushing syndrome.

Question 10

Lithium common s/e

Answer 10

Polyuria, polydipsia, tremor, mental confusion at higher doses

Question 11

Depakote s/e

Answer 11

GI upset, sedation, tremor at high doses

Question 12

Risk of MDD suicide

Answer 12

10-15%

Question 13

MAOI side effects

Answer 13

hypotension but fewer anticholinergic effects

Question 14

Lacunar strokes on CT/MRI

Answer 14

Hypointensities in subcortical areas

Question 15

Carbohydrate deficient Transferrin

Answer 15

In alcoholics, transferrin has fewer mono-saccharides attached so an increased ratio of 0,1,2 chain sugars to longer chain sugars is a test for high ethanol intake

Question 16

SCZ and suicide

Answer 16

30% attempt, 10% complete

Question 17

MDD and suicide

Answer 17

10-15%

Question 18

Infarcts and the brain

Answer 18

● Infarcts of the left frontal hemispheres (part of left middle cerebral artery distribution) present with depression whereas on the right frontal hemisphere present with euphoia, inappropriate indifference, or mania.

Question 19

OCD and brain activity

Answer 19

Increased activity in caudate nucleus, cingulum, and frontal lobes

Question 20

SCZ and brain

Answer 20

Smaller hippocampus, parahippocampal gyrus, and amygdala

Question 21

Verbigeration

Answer 21

Repetitive and Meaningless Talk

Question 22

Dysarthria

Answer 22

Difficulty in articulation

Question 23

Glosolalia

Answer 23

ability to speak a new language suddenly

Question 24

Don’t use MAOIs and TCAs in these conditions

Answer 24

○ Don’t use in cardiac conduction disease, constipation, glaucoma, or prostatic hypertrophy

Question 25

Valproate side effects

Answer 25

: mild transaminitis, alopecia, thrombocytopenia and impaired platelet function, up to fatal hepatotoxicity, pancreatitis, agranulocytosis

Question 26

Lamictal s/e

Answer 26

: Ataxia, blurred vision, diplopia, dizziness, nausea, and vomiting
■ SJS is greater in pediatric patients

Question 27

Oxcarbazepine benefits

Answer 27

like carbamazepine but fewer side effects and drug interactions, don’t need to monitor

Question 28

trihexyphenidyl

Answer 28

anticholinergic like cogentin

Question 29

ramelteon

Answer 29

pushes melatonin