Adult Nutrition Flashcards
Dietary Guidelines for Americans:
Goals
- Maintain healthy weight
- Chronic disease prevention
- Adequate nutrient intake
What do Americans need to improve on in their diet?
- Maintain calorie balance
- Increase whole grains and reduce refined sugars
- Increase fruits & vegetables
- Especially dark green, red/orange, beans/peas
- Increase heart healthy fats especially proteins from seafood/fish
- Reduce sodium
- What is the gold standard for determining calorie need?
- What is normal nutritional energy (kcal/kg)?
- How many calories are recommended for:
- Women
- Men
- When should caloric intake be increased?
- Gold standard: indirect calorimetry
- Normal nutrition: 25-35 kcal/kg
- Calories
- 1200-2000 for women
- 1800-2400 for men
-
Increased calorie needs:
- Infection, critical illness, wound healing, chronic illness, cancer
Macronutrient Distribution
Carbs, Proteins, Fats
What is the role of carbohydrate intake?
- Supports energy metabolism
- Maintains blood glucose
- Immediate source of energy for brain
- Maintains glycogen stores in liver
Dietary Fiber:
Soluble vs. Insoluble
-
Soluble
- Forms gel-like substance in intestines
-
Food sources:
- Oats, barley, fruits, vegetables, dried peas/beans
-
Insoluble
- Increases stool bulk
-
Food source:
- Bran, vegetables with skins, skins on fruits
Protein
- Requirements:
- Healthy Adults
- Non-healthy adults
- Food Sources:
- How are proteins involved in underfeeding the obese?
-
Requirements:
- Healthy adults 0.8g/kg
- Critical illness, cancer, wound healing/pressure ulcers: 1.2-2.0g/kg
-
Food sources:
- Meats, dairy, eggs, soy products
-
Permissive underfeeding of obese
- Decreased calories, increased protein
Fat recommendations:
-
Saturated fats:
- Function?
-
Unsaturated fats:
- Function?
-
Limit saturated fats
- Increases LDL cholesterol, heart disease risk
-
Increase monounsaturated fats and omega-3 polyunsaturated fats
- Decreases LDL cholesterol
- Decrease inflammation
- Improves HDL cholesterol
- What is malnutrition?
- What are the consequences of malnutrtion?
-
Decreased intake and increased nutrient needs
- Weight loss, loss of lean body mass
-
Consequences of malnutrition:
- Increased morbidity & mortality
- Decreased functional capacity
- Decreased quality of life
- Increased length of stay
- Increased hospital costs
What are the diagnostic criteria for malnutrition?
- Insufficient energy intake
- Weight loss
- Loss of muscle mass
- Loss of subcutaneous fat
- Localized or generalized fluid accumulation
- Diminished functional status as measured by handgrip strength
Vitamin B1 (thiamine):
- Role
- Food Sources
-
RDA
- Men
- Women
- Role: Energy metabolism
-
Food sources:
- Pork, enriched & whole grains, legumes
-
RDA:
- Men: 1.2 mg/day
- Women: 1.1 mg/day
What two disease processes are caused by a thiamine deficiency?
- Wernicke-Korsakoff
- Dry/Wet Beriberi (severe deficiency)
Thiamine (Vitamin B1) deficiency:
- Symptoms
- Wernicke-Korsakoff
- Dry/Wet Beriberi
- Labs?
-
Symptoms
- Decreased appetite, fatigue, peripheral neuropathy
-
Wernicke-Korsakoff
- Mental confusion (Wernicke’s encephalopathy)
- Ataxia
- Uncoordinated eye movements
-
Dry/Wet Beriberi—severe deficiency
- Advanced neuromuscular symptoms
- Edema (wet Beriberi)
- Heart failure
- Labs: serum thiamine
Vitamin B2 (Riboflavin):
- Role
- Food Sources
-
RDA
- Men
- Women
- Role: Energy metabolism
-
Food sources
- Milk, dairy products, eggs, enriched cereals, dark leafy greens
-
RDA
- Males: 1.3 mg/day
- Females: 1.1 mg/day
Riboflavin (Vitamin B2)** deficiency:**
- Symptoms:
- Toxicity:
-
Symptoms:
- Cheilitis, glossitis, dermatitis, anemia
-
Toxicity:
- Rare
Vitamin B3 (Niacin):
- **Role **
- **Food sources **
-
RDA
- Men:
- Women:
- Role: Energy metabolism
-
Food sources
- Meats, legumes
- Synthesize from tryptophan
- 1 mg niacin per 60 mg tryptophan
-
RDA
- Men: 16 mg/day
- Women: 14 mg/day
Niacin (Vitamin B3)** **Deficiency:
- Symptoms:
- Toxicity
- What is the therapeutic use for Nicotinic Acid?
-
Symptoms: Glossitis
-
Pellagra (Three “D”s)
- Diarrhea, Dermatitis, Dementia…Death
-
Pellagra (Three “D”s)
-
Toxicity
- Histamine induced flushing, liver damage
-
Therapeutic Use for Nicotinic Acid:
- Used to treat elevated cholesterol
Vitamin B5 (Pantothenic Acid):
- **Role: **
- Adequate Intake (AI)
- Food sources
- **Deficiency & toxicity **
- Role: Energy metabolism
-
Adequate Intake (AI)
- 5 mg/day
-
Food sources
- Widespread
- Legumes/lentils, whole grains, sweet potatoes, meat
- Deficiency & toxicity rare
Vitamin B6 (Pyridoxine):
- **Role: **
- Food sources:
- RDA
- Role: Energy metabolism
-
Food sources:
- Plants & animal sources
- Potatoes, chicken, salmon, nuts, fortified cereals
-
RDA
- 1.3 mg/day
**Pyridoxine **(Vitamin B6) deficiency:
- Symptoms
- Toxicity
-
Symptoms
- Irritability, nervousness, depression, peripheral neuropathy (severe)
- Microcytic anemia
-
Toxicity
- Neurotoxicity, photosensitivity
Vitamin B7 (Biotin):
- **Role: **
- Food sources
- Adequate Intake (AI)
- Deficiency
- Role: Energy metabolism
-
Food sources
- Widely distributed
- Egg yolks, liver, yeast, whole grains, vegetables
-
Adequate Intake (AI)
- 30 mcg per day
-
Deficiency
- Hair loss
**Vitamin B9 (Folate): **
- **Role: **
- Food sources:
- RDA
- Role: Hematopoietic
-
Food sources:
- Liver, dark leafy vegetables, broccoli, legumes
- Fortified grains/cereals
-
RDA
- 400 mcg/day
Folate (Vitamin B9) Deficiency:
- Symptoms
- Toxicity
- Labs:
-
Symptoms
- Macrocytic or megaloblastic anemia, hyperhomocysteinemia, red tongue, cognitive decline, neural tube defects
-
Toxicity
- Rare
- May mask Vitamin B12 deficiency
-
Labs:
- Serum folate, RBC folate, CBC
Vitamin B12 (Cobalamin):
- **Role: **
- Food sources:
- RDA:
- Role: Hematopoietic
-
Food sources:
- Only animal sources
- Meat and meat products
-
RDA:
- 2.4 mcg/day
Cobalamin (Vitamin B12) Deficiency
- Symptoms:
- Who is at risk for this deficiency?
- Labs:
-
Symptoms:
- Megaloblastic anemia, pernicious anemia, homocysteine, neurological deterioration
-
At risk:
- Vegans, elderly, insufficient intrinsic factor/HCl in stomach
-
Labs:
- Serum B12, Methylmalonyl Co-A, Complete Blood Count
**Vitamin C (Ascorbate): **
- Food Sources:
-
RDA
- Men
- Women
- *increased for ….
-
Food sources:
- Plant sources
- Citrus fruits, dark leafy greens, strawberries, bell peppers, cantaloupe
-
RDA
- Men: 90 mg/day
- Women: 70 mg/day
- *increased for smokers
Ascorbate (Vitamin C) Deficiency:
- Symptoms:
- What can severe deficiency cause?
-
Symptoms
- Easy bruising, petechiae, decreased immunocompetence
- Severe deficiency ⇒ **Scurvy (4 “H s”) **
- Hemorrhage, Hyperkeratosis, Hypochondriasis, Hematologic abnormalities
Ascorbate (Vitamin C):
- Toxicity/Excessive intake
- Upper Limit:
-
Toxicity/Excessive intake
- Hyperoxaluria
- Increased risk for renal oxalate stones
- Diarrhea
- Iron overdose
- Hyperoxaluria
- Upper Limit: 2000 mg/day
Vitamin E (Tocopherol):
- Role:
- Food Sources
-
Adequate Intake (AI)
- Males:
- Females:
- Role: Antioxidant
-
Food Sources
- Plant oils, nuts, seeds, almonds, hazelnuts
-
Adequate Intake (AI)
- Males: 15 mg alpha-tocopherol/day
- Females: 15 mg per day
Tocopherol (Vitamin E):
- Inadequate intake
- Deficiency
- Toxicity
-
Inadequate intake
- Majority of Americans do not meet guidelines
-
Decreased antioxidant protection
- Aging, arthritis, cancer, CVD, Alzheimer’s disease, infection…
-
Deficiency—rare
- Neuromuscular degeneration
-
Toxicity
- Low risk
Vitamin A (Carotenes, Retinoids):
- Functions
-
Food Sources
- Retinol
- Carotenoids
- RDA
-
Functions
- Cell differentiation, vision
-
Food Sources
- Retinol
- Animals Sources—fish oils
- Carotenoids
- Plant foods—orange vegetables, dark leafy greens
- Retinol
-
RDA
- Men: 3,000 IU
- Women: 2,333 IU
Vitamin A:
- Deficiency Symptoms:
-
Toxicity
- Excessive intake of ….
- Important labs:
-
Deficiency Symptoms:
- Night blindness, poor growth, xerophthalmia, follicular hyperkeratosis
-
Toxicity
- Excessive intake of retinol
- Very low risk of toxicity from carotenoids
- Anorexia, dry itchy skin, hair loss, abnormal liver function
- Fetal malformations
- Excessive intake of retinol
- Important labs: Plasma Retinol
- What is the key micronutrient of importance in the elderly?
Sodium
What foods increase sodium?
- processed foods
- restaurant/fast food
- canned foods
- meats
- bread
- condiments
- cured meats
- pickled/fermented foods
- seasonings with salt
RDA for sodium intake:
- < 2,300 mg/day = 1 tsp:
- 1500 mg/day:
-
< 2,300 mg/day = 1 tsp:
- Healthy Americans over age 2
-
1,500 mg/day:
- Adults age 51 or older All African Americans Chronic disease
- Kidney disease
- Hypertension
- Congestive heart failure
- Liver failure