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Year 2 > Adrenergics > Flashcards

Adrenergics Flashcards

1
Q

phenylephrine

A 
a1 > a2 
hypotensive emergencies (hemorrhagic shock), overdose antihypertensives, cns depressants, decongestion of muscous membranes, exam of retina
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2
Q

clonidine

A

htn, glaucoma

a2 > a1

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3
Q

norepiephrine

A

a1 = a2, B1

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4
Q

epinephrine

A

a1 = a2, B1 = B2

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5
Q

dobutamine

A

B1 > B2, a1 (-) isomer is an agonist, a1 (+) isomer is a antagonist

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6
Q

isoproterenol

A

B1 =B2

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7
Q

albuterol

A

B2 > B1

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8
Q

cocaine

A

dopamine and NE re-up inhibitor

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9
Q

phenelzine

A

inhib MAO

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10
Q

selegiline

A

inhib MAO

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11
Q

amphetamines

A

increase dopamine, NE, inhibits reuptake

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12
Q

methylphenidate

A

increase dopamine, NE, inhibits reuptake

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13
Q

tyramine

A

diagnostic peripheral adrenergic fxn, doesn’t cross BB, decarbo product of tyrosine, MAO metabolized in liver, increases NE at a1 smooth m

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14
Q

ephedrine

A

ephedrine

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15
Q

phentolamine

A

a1 =a2 antagonist

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16
Q

phenoxybenzamine

A

a1 =a2 antagonist

17
Q

prazosin

A

a1 antagonist

18
Q

tamsulosin

A

a1 antagonist

19
Q

doxazosin

A

a1 antagonist

20
Q

labetalol

A

partial agonist B and a1

21
Q

carvedilol

A

inverse agonist B and a1 blocker

22
Q

propranolol

A

antagonist B1 =B2 blocker

23
Q

pindolol

A

partial agonist B1 =B2 blocker

24
Q

nadolol

A

antagonist B1 =B2 blocker

25
Q

metoprolol

A

inverse agonist selective b1

26
Q

betaxolol

A

inverse agonist selective b1

27
Q

acebutolol

A

partial agonist selective b1

Year 2 (10 decks)

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