Adrenergics Flashcards
Direct alpha-1 adrenergic agonist + their clinical uses
Dopamine: Cardiac resus
Phenylephrine: Nasal Decongestant
Direct alpha-2 adrenergic agonist + their clinical uses
Brimonidine: Glaucoma
Direct non-selective alpha adrenergic agonist + their clinical uses
Oxymetazoline: Nasal decongestant
Direct beta-1 adrenergic agonist + their clinical uses
Dobutamine: Congestive heart failure
Dopamine: Cardiac resus
Direct beta-2 adrenergic agonist + their clinical uses
Salbutamol/Tetraline: Asthma and labour
Direct beta 3 adrenergic agonist + their clinical uses
Mirabegron: urinary incontinence
Direct non selective beta adrenergic agonist + their clinical uses
Isoprenaline: Asthma & cardiac resus
Indirect adrenergic agonist that acts as a MAOA inhibitor
Moclobemide
Indirect adrenergic agonist that blocks NE uptake
Tricyclic antidepressants
Indirect adrenergic agonist that displaces endogenous NE
Ephrine & pseudoephrine
Direct alpha adrenergic antagonist (alpha blocker) + clinical use
Prazosin: hypertension
Phenoxybenzamine: pheochromocytoma
Direct beta-1 selective adrenergic antagonist (beta blocker) + clinical use
Bisoprolol: hypertension
Betaoxlol: glaucoma
Direct non-selective beta adrenergic antagonist (beta blocker) + clinical use
Propanolol: hypertension
Timolol: glaucoma
Sotalol: arrhythmia
Indirect adrenergic antagonist that acting as an agonist at presynaptic autoreceptors
Dexmedetomidine
Indirect adrenergic antagonist that decreases NE synthesis (explain how)
Methyldopa:
Inhibtion of tyrosine hydroxylase, rate limiting enzyme in NE synthesis