Adrenergic Transmission Flashcards
Non selective adrenergic agonists
Noradrenaline
Adrenaline
Oxymetazoline
Isoprenaline
Selective alpha agonists
Phenylephrine (a1)
Methoxamine (a1)
Clonidine (a2)
Selective beta agonists
Dobutamine (b1)
Terbutaline (b2)
Salbutamol (b2)
Inhibiting synthesis of adrenaline/noradrenaline
Carbidopa (DOPA decarboxylase)
Methyldopa (DOPA decarboxylase)
a-methyl-p-tyrosine (tyrosine hydroxylase)
Sympathomimetic drugs
Amphetamine
Tyramine
Ephedrine
Drugs inhibiting NA uptake
Reserpine
Imipramine (inhibit NET)
Cocaine (inhibit NET)
Drugs inhibiting synthesis/release of NA
a-methyldopa (false NA precursor)
Guanethidine (deplete stored NA)
Non selective alpha adrenoceptor antagonists
Phentolamine
Phenoxybenzamine
Selective alpha adrenoceptor antagonists
Prazosin (a1)
Doxazocin (a1)
Yohimbine (a2)
Non selective beta adrenoceptor antagonists
Propranolol
Timolol
Sotalol
Selective beta1 adrenoceptor antagonists
Atenolol Bisoprolol Metoprolol Pindolol Acebutolol Nebivolol
Mixed adrenoceptor antagonists
Labetalol (a/b)
Carvedilol (a1/b)