Adrenergic Stimulants

Question 1

Norepi (levophed)

Answer 1

Mostly alpha, and beta 1 some beta 2
IV only
Rarely used-increase BP in hypotension (baroreflex)
SE: severe vasoconstriction, necrosis

Question 2

Epinephrine (adrenaline)

Answer 2

Activates all adrenergic mostly beta and some alpha
DOC anaphylactic shock, also glaucoma, MI, IM drug assist
*high dose=alpha 1 which will override and vasoconstrict
SE tremor, HA, HTN, tachycardia

Contra: pt on beta blocker (a activity will go unchecked = severe HTN)

Question 3

Phenylephine (neofrin)

Answer 3

Alpha1 selective agonist
Tx for hypotension, nasal decongestant, **dilate eye for exam and keep accommodation in tact

SE rebound congestion, caution in pt with HTN/BPH

Question 4

Pseudoephedrine (Sudafed)

Answer 4

Alpha 1 agonist
Hypotension, *decongestant
Caution if HTN and BPH

*highly regulated

Question 5

Oxymetazoline (Afrin)

Answer 5

Alpha 1 agonist
Topically for vasoconstriction in eye/nasal mucosa

Caution if pt has CAG or HTN

Question 6

Clonidine (catapes)

Answer 6

Alpha 2 agonist- decrease symp output
Tx HTN, craving in addicts

SE mouth dryness, sedation (CNS effects)
DO NOT suddenly stop clonidine

Question 7

Methyldopa (aldumet)

Answer 7

Alpha 2 agonist- decrease symp output
DOC for prego HTN, decrease hot flashes

Mouth dryness and Sedation

Question 8

Tizanidine (zanaflex)

Answer 8

Alpha 2 agonist
*less BP affect
Tx muscle spacsticity in neuro

SE Athenians loss of tone

Question 9

Isoproterol (isupel)

Answer 9

Beta agonist
ED tx for cardiac arrest and heart block (very potent vasodilator)

SE tachy, palpitation, arrhythmia

Question 10

Dobutamine (dobutrex)

Answer 10

IV Beta 1 agonist
Increase cardiac * contractility
Used for stress testing

SE HTN worsens if given quicklyq

Question 11

Albuterol (ventolin)

Answer 11

Beta 2 agonist
Asthma tax-dilator

SE tachycardia, tremor

Question 12

Mirabegro (myrbetriq)

Answer 12

B3 agonist
Tax for *overactive bladder, relaxes detrusor muscle

SE HTN, tachy

Question 13

Dopamine

Answer 13

Low-D1 kidney-renal vasodilation
Mod-B1 heart- inotropic
High dose-alpha-vasoconstriction

Don’t use with MAO inhib

Question 14

Fenoldopam

Answer 14

Only D1 agonist
Tx emergency HTN
SBP >180 AND end organ dysfunction

SE tachy, flushing

Question 15

Amphetamine (adderall)
Methylphenidate (Ritalin)
Methamphetamine (desoxyn)

Answer 15

CNS stim-release NE by geetting taken up by NET and displacing NE
DOC for ADHD
Meth has most CNS effects

SE tremor, psychosis, HTN

Question 16

Coke

Answer 16

Rarely used as anesthetic vasoconstrictor for dental procedure
Inhibit reputable of DA and NE
SE HTN stroke in healthy people : tachy, arrhythmia, MI, psychosis

Question 17

Tyramine

Answer 17

In food
Release catecholamines which form a fals transmitter
If pt on MAOI for depression they need to avoid these foods cause they’ll get HTN