Adrenergic Receptors Flashcards
Major blood vessel and vasculature in dermal, GI, renal, bladder, and nasal membranes.
***(excludes skeletal and hepatic)
Alpha-1
Constriction, ⬆️ peripheral resistance, ⬆️ diastolic blood pressure.
⬆️BP but ⬇️ HR (alpha-1 sympathomimetic)
Contraction of radial muscles–>–>mydriasis
dilation of pupil
Alpha-1
Eye
Constrict sphincters, ⬇️ outflow
Alpha-1
Bladder and GI sphincters
⬇️ production of aqueous humor
Alpha-2
Eye
⬇️ insulin release–>–>⬆️blood glucose
Alpha-2
Pancreatic islets
⬇️ neurotransmitter release
Alpha-2
Pre-synaptic nerve terminals
⬇️ blood pressure
***Inhibits baroreflex
Alpha-2
CNS
Brainstem
Inhibit pain transmission
Alpha-2
Spinal cord
Nasal Constriction
Alpha-2
Nasal vasculature
⬆️ heart rate, ⬆️ con tactility, ⬆️ force–>–>⬆️cardiac output
Beta-1
Heart
⬆️renin secretion –>–>vasoconstriction
Beta-1
Kidney
⬆️production of aqueous humor
Beta-1
Eye
Relaxation, ⬆️blood flow to liver and skeletal muscle
Beta-2
Hepatic and skeletal muscle vascular smooth muscle
Relaxation–>–>⬆️airflow
Beta-2
Pulmonary smooth muscle
Relaxation, ⬇️ motility
Beta-2
GI long. Smooth muscle