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Pharmacology > Adrenergic Drugs > Flashcards

Adrenergic Drugs Flashcards

1
Q

Sympathetic Nervous System

A

Flight or flight

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2
Q

Parasympathetic Nervous System

A

Rest and Digest

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3
Q

Adrenergic Drugs effect which nervous system

A

Sympathetic Nervous system

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4
Q

Adrenergic Drugs mimic the effects of what neurotransmitters?

A

Epinephrine, norepinephrine, and dopamine

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5
Q

Alpha-1 Adrenergic Receptors are located

A

Vascular smooth muscles, eyes, bladder, liver, and kidney

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6
Q

Alpha-2 Adrenergic Receptors are located

A

presynaptic nerve endings which inhibits the release of NE

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7
Q

Alpha Adrenergic Agonist Drug Responses Include

A

Vasoconstriction and Central Nervous Stimulation

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8
Q

Beta-1 receptors are primarily located in the

A

heart

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9
Q

Beta-2 receptors are primarily located in the

A

Lungs

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10
Q

Beta-Adrenergic Agonist Responses

A

Bronchial, GI, and uterine smooth muscle relaxation. Glycogenolysis (release of glucose). And Cardiac Stimulation

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11
Q

Dopaminergic receptors, stimulated by dopamine causes

A

Dilation of blood vessels in the kidneys, mesenteric, coronary, and cerebral areas.

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12
Q

Catecholamines include

A

epinephrine, norepinephrine, dopamine(endogenous) and Dobutamine and Phenylephrine (synthetic)

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13
Q

Stimulation of A-1 receptors on smooth muscles causes

A

vasoconstriction, relaxation of GI muscles, constriction of bladder sphincter, contraction of uterus, male ejaculation, and dilation of pupils

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14
Q

Stimulation of B-1 receptors on the myocardium, AV node, and SA node result in

A

Increased force of contraction (positive inotropic effect)
Increased heart rate (positive chronotropic effect)
Increased conduction through the AV node (positive dromotropic effect)

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15
Q

Positive Inotropic Effect

A

Increased Force of Contraction

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16
Q

Positive Chronotropic Effect

A

Increased Heart Rate

17
Q

Positive Dromotropic Effect

A

Increased conduction through the AV Node

18
Q

B-2 Adrenergic Receptors stimulate

A

the airways, causing bronchodilation, uterine relaxation, glycogenolysis, and relaxation of GI smooth muscles

19
Q

What are indications of needing an adrenergic agonist drug

A

Respiratory- Acute and chronic bronchial asthma, emphysema, bronchitis, nasal congestion
Ophthalmic - conjunctival congestion, needing a reduction in intraocular pressure, open-angle glaucoma
Bladder - over active bladder
Cardiovascular - cardiac failure or shock (V-fib or Asystole)

20
Q

Contraindications of adrenergic agonist

A

A known drug allergy, severe hypertension

21
Q

Adverse effects of Alpha Adrenergic Drugs

A

Chest pain, vasoconstriction, hypertension, palpitations, dysthymias

22
Q

Adverse effects of Bets Adrenergic Drugs

A

Increased heart rate, palpitations, and fluctuations in blood pressure

23
Q

Toxicity of adrenergic agonist causes an extension of what adverse effects?

A

Seizures, hypotension or hypertension, dysthymias, palpitations. The two most life threatening involve CNS and cardiovascular

24
Q

Treatment for adrenergic agonist is

A

Stop medication, give an adrenergic blockers or a cholinergic, and manage symptoms

25
Q

Adrenergic Drugs include these types of medications

A

Bronchodilators, ophthalmic, nasal decongestants, and vasoactive medications.

26
Q

Vasoactive adrenergic drugs are used to treat

A

Shock.

27
Q

Vasoactive Adrenergic Drugs, all given by IV, include:

A

Dopamine, Epinephrine, Norepinephrine, Dobutamine, and Phenylephrine

28
Q

Dobutamine (Dubutrex)

A

Beta-1 selective vasoactive drug, increases cardiac output

29
Q

Where is the epinephrine strength 1/1000 administered?

A

SubQ

30
Q

Where is the epinephrine strength 1/10,000 administered?

A

Given via IV

31
Q

Low doses of epinephrine stimulate

A

Beta-1 receptors which increases the force of contraction and increased heart rate

32
Q

High doses of epinephrine stimulate

A

Mostly Alpha receptors which will increase blood pressure

Pharmacology (5 decks)

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